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The objective of this study is to derive functional networks for the autism spectrum disorder (ASD) population using the group ICA and dictionary learning model together and to classify ASD and typically developing (TD) participants using…

神经元与认知 · 定量生物学 2021-06-17 Xin Yang , Ning Zhang , Donglin Wang

Human brains lie at the core of complex neurobiological systems, where the neurons, circuits, and subsystems interact in enigmatic ways. Understanding the structural and functional mechanisms of the brain has long been an intriguing pursuit…

神经元与认知 · 定量生物学 2022-07-26 Hejie Cui , Wei Dai , Yanqiao Zhu , Xiaoxiao Li , Lifang He , Carl Yang

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

计算机视觉与模式识别 · 计算机科学 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath

The study of hierarchy in networks of the human brain has been of significant interest among the researchers as numerous studies have pointed out towards a functional hierarchical organization of the human brain. This paper provides a novel…

神经元与认知 · 定量生物学 2021-03-02 Dushyant Sahoo , Theodore D. Satterthwaite , Christos Davatzikos

We study the impact of the brain tractography false positives in the brain connectivity graphs. The representative input database for the analysis is the set of tractograms from the participants on the ISMRM-2015 Tractography Challenge. We…

社会与信息网络 · 计算机科学 2023-05-26 Juan Luis Villarreal-Haro , Alonso Ramirez-Manzanares , Juan Antonio Pichardo-Corpus

Resting-state functional magnetic resonance imaging (fMRI) has emerged as a cornerstone for psychiatric diagnosis, yet most approaches rely on pairwise brain cortical or sub-cortical connectivities that overlooks higher-order interactions…

机器学习 · 计算机科学 2026-04-21 Kunyu Zhang , Qiang Li , Vince D. Calhoun , Shujian Yu

The properties of functional brain networks strongly depend on how their nodes are chosen. Commonly, nodes are defined by Regions of Interest (ROIs), pre-determined groupings of fMRI measurement voxels. Earlier, we have demonstrated that…

神经元与认知 · 定量生物学 2019-11-25 Elisa Ryyppö , Enrico Glerean , Elvira Brattico , Jari Saramäki , Onerva Korhonen

Advanced brain imaging techniques make it possible to measure individuals' structural connectomes in large cohort studies non-invasively. The structural connectome is initially shaped by genetics and subsequently refined by the environment.…

应用统计 · 统计学 2018-06-11 Zhengwu Zhang , Genevera I. Allen , Hongtu Zhu , David Dunson

Brain activation and connectivity analyses in task-based functional magnetic resonance imaging (fMRI) experiments with multiple subjects are currently at the forefront of data-driven neuroscience. In such experiments, interest often lies in…

应用统计 · 统计学 2019-04-02 Daniel Spencer , Rajarshi Guhaniyogi , Raquel Prado

Diffusion tractography in brain connectomics often involves tracing axonal trajectories across gray-white matter boundaries in gyral blades of complex cortical convolutions. To date, gyral bias is observed in most tractography algorithms…

神经元与认知 · 定量生物学 2019-04-15 Ye Wu , Yoonmi Hong , Yuanjing Feng , Dinggang Shen , Pew-Thian Yap

Mammalian tissue architecture is central to biological function, and its disruption is a hallmark of disease. Medical imaging techniques can generate large point cloud datasets that capture changes in the cellular composition of such…

The human brain is a complex system requiring both macroscopic and microscopic components for comprehensive understanding. However, mapping nonlinear relationships between these scales remains challenging due to technical limitations and…

图像与视频处理 · 电气工程与系统科学 2025-10-28 Sooyoung Kim , Joonwoo Kwon , Junbeom Kwon , Jungyoun Janice Min , Sangyoon Bae , Yuewei Lin , Shinjae Yoo , Jiook Cha

In the last two decades, functional magnetic resonance imaging (fMRI) has emerged as one of the most effective technologies in clinical research of the human brain. fMRI allows researchers to study healthy and pathological brains while they…

神经元与认知 · 定量生物学 2022-12-06 Sadi Md. Redwan , Md Palash Uddin , Muhammad Imran Sharif , Anwaar Ulhaq

This article focuses on a multi-modal imaging data application where structural/anatomical information from gray matter (GM) and brain connectivity information in the form of a brain connectome network from functional magnetic resonance…

The human brain is a complex system, and understanding its mechanisms has been a long-standing challenge in neuroscience. The study of the functional connectome, which maps the functional connections between different brain regions, has…

神经与进化计算 · 计算机科学 2025-04-14 Tananun Songdechakraiwut , Yutong Wu

One of the most well-established tools for modeling the brain as a complex system is the functional connectivity network, which examines the correlations between pairs of interacting brain regions. While powerful, the network model is…

信息论 · 计算机科学 2022-06-15 Thomas F. Varley , Maria Pope , Joshua Faskowitz , Olaf Sporns

Diffusion-weighted magnetic resonance imaging (DW-MRI) allows for non-invasive imaging of the local fiber architecture of the human brain at a millimetric scale. Multiple classical approaches have been proposed to detect both single (e.g.,…

Shape measures have emerged as promising descriptors of white matter tractography, offering complementary insights into anatomical variability and associations with cognitive and clinical phenotypes. However, conventional methods for…

图像与视频处理 · 电气工程与系统科学 2025-10-22 Yui Lo , Yuqian Chen , Dongnan Liu , Leo Zekelman , Jarrett Rushmore , Yogesh Rathi , Nikos Makris , Alexandra J. Golby , Fan Zhang , Weidong Cai , Lauren J. O'Donnell

A central question for neuroscience is how to characterize brain representations of perceptual and cognitive content. An ideal characterization should distinguish different functional regions with robustness to noise and idiosyncrasies of…

神经元与认知 · 定量生物学 2024-10-17 Baihan Lin , Nikolaus Kriegeskorte

Brain decoding is a hot spot in cognitive science, which focuses on reconstructing perceptual images from brain activities. Analyzing the correlations of collected data from human brain activities and representing activity patterns are two…

计算机视觉与模式识别 · 计算机科学 2017-12-06 Siyu Yu , Nanning Zheng , Yongqiang Ma , Hao Wu , Badong Chen