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Primary visual cortex (V1) provides crucial insights into the selectivity and emergence of specific output features such as orientation tuning. Tuning and selectivity of cortical neurons in mouse visual cortex is not equivocally resolved so…

A growing body of work has begun to study intervention design for efficient structure learning of causal directed acyclic graphs (DAGs). A typical setting is a causally sufficient setting, i.e. a system with no latent confounders, selection…

We introduce and analyze a class of neural network models motivated by the Drosophila central complex nervous system, designed to capture the emergence and dynamics of orientation-selective activity bumps. Starting from a biologically…

动力系统 · 数学 2026-04-22 S. Ismail , B. Ambrosio , M. A. Aziz-Alaoui , Y. Souleiman

Schemas are knowledge structures that can enable rapid learning. Rodent one-shot learning in a multiple paired association navigation task has been postulated to be schema-dependent. We still only poorly understand how schemas,…

神经与进化计算 · 计算机科学 2024-09-11 M Ganesh Kumar , Cheston Tan , Camilo Libedinsky , Shih-Cheng Yen , Andrew Yong-Yi Tan

Proteins control many vital functions in living cells, such as cell growth and cell division. Reliable coordination of these functions requires the spatial and temporal organizaton of proteins inside cells, which encodes information about…

生物物理 · 物理学 2022-02-22 Tom Burkart , Manon C. Wigbers , Laeschkir Würthner , Erwin Frey

Soft robots pose difficulties in terms of control, requiring novel strategies to effectively manipulate their compliant structures. Model-based approaches face challenges due to the high dimensionality and nonlinearities such as hysteresis…

The computational capabilities of a neural network are widely assumed to be determined by its static architecture. Here we challenge this view by establishing that a fixed neural structure can operate in fundamentally different…

神经与进化计算 · 计算机科学 2025-09-24 Xia Chen

The quintessential property of neuronal systems is their intensive patterns of selective synaptic connections. The current work describes a physics-based approach to neuronal shape modeling and synthesis and its consideration for the…

神经元与认知 · 定量生物学 2009-11-10 Luciano da Fontoura Costa , Regina Celia Coelho

Connecting neural activity to function is a common aim in neuroscience. How to define and conceptualize function, however, can vary. Here I focus on grounding this goal in the specific question of how a given change in behavior is produced…

神经元与认知 · 定量生物学 2023-11-14 Grace W. Lindsay

There is a concerted effort to build domain-general artificial intelligence in the form of universal neural network models with sufficient computational flexibility to solve a wide variety of cognitive tasks but without requiring…

神经与进化计算 · 计算机科学 2023-03-27 Jascha Achterberg , Danyal Akarca , Moataz Assem , Moritz Heimbach , Duncan E. Astle , John Duncan

In this paper we present a computational modeling account of an active self in artificial agents. In particular we focus on how an agent can be equipped with a sense of control and how it arises in autonomous situated action and, in turn,…

人工智能 · 计算机科学 2021-12-13 Sebastian Kahl , Sebastian Wiese , Nele Russwinkel , Stefan Kopp

Modeling the behavior of coupled networks is challenging due to their intricate dynamics. For example in neuroscience, it is of critical importance to understand the relationship between the functional neural processes and anatomical…

机器学习 · 计算机科学 2021-04-20 Hongyuan You , Sikun Lin , Ambuj K. Singh

The artificial axon is an excitable node built with the basic biomolecular components and supporting action potentials. Here we demonstrate coincidence firing (the AND operation) and other basic electrophysiology features such as increasing…

生物物理 · 物理学 2017-11-22 Hector Vasquez , Giovanni Zocchi

Learning weights in a spiking neural network with hidden neurons, using local, stable and online rules, to control non-linear body dynamics is an open problem. Here, we employ a supervised scheme, Feedback-based Online Local Learning Of…

神经元与认知 · 定量生物学 2019-02-19 Aditya Gilra , Wulfram Gerstner

Generative Adversarial Networks (GANs) have recently achieved impressive results for many real-world applications, and many GAN variants have emerged with improvements in sample quality and training stability. However, they have not been…

计算机视觉与模式识别 · 计算机科学 2018-12-11 David Bau , Jun-Yan Zhu , Hendrik Strobelt , Bolei Zhou , Joshua B. Tenenbaum , William T. Freeman , Antonio Torralba

Collective cell migration is crucial in many biological processes such as wound healing, tissue morphogenesis, and tumor progression. The leading front of a collective migrating epithelial cell layer often destabilizes into multicellular…

生物物理 · 物理学 2020-05-07 Yanjun Yang , Herbert Levine

Accurately inferring Gene Regulatory Networks (GRNs) is a critical and challenging task in biology. GRNs model the activatory and inhibitory interactions between genes and are inherently causal in nature. To accurately identify GRNs,…

Neural architectures inspired by our own human cognitive system, such as the recently introduced world models, have been shown to outperform traditional deep reinforcement learning (RL) methods in a variety of different domains. Instead of…

神经与进化计算 · 计算机科学 2019-06-24 Sebastian Risi , Kenneth O. Stanley

We propose a mechanism enabling the appearance of border cells -- neurons firing at the boundaries of the navigated enclosures. The approach is based on the recent discovery of discrete complex analysis on a triangular lattice, which allows…

神经元与认知 · 定量生物学 2023-05-09 Y. Dabaghian

Using predictive models to identify patterns that can act as biomarkers for different neuropathoglogical conditions is becoming highly prevalent. In this paper, we consider the problem of Autism Spectrum Disorder (ASD) classification where…

机器学习 · 统计学 2018-10-31 Rushil Anirudh , Jayaraman J. Thiagarajan