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Markov state models (MSMs) have been widely used to analyze computer simulations of various biomolecular systems. They can capture conformational transitions much slower than an average or maximal length of a single molecular dynamics (MD)…

生物大分子 · 定量生物学 2018-02-14 Anton V. Sinitskiy , Vijay S. Pande

We study the existence of densities for distributions of piecewise deterministic Markov processes. We also obtain relationships between invariant densities of the continuous time process and that of the process observed at jump times. In…

概率论 · 数学 2020-06-03 Piotr Gwiżdż , Marta Tyran-Kamińska

The stochastic trajectories of molecules in living cells, as well as the dynamics in many other complex systems, often exhibit memory in their path over long periods of time. In addition, these systems can show dynamic heterogeneities due…

We call a multidimensional distribution to be decomposable with respect to a partition of two sets of coordinates if the original distribution is the product of the marginal distributions associated with these two sets. We focus on the…

概率论 · 数学 2014-12-02 J. G. Dai , Masakiyo Miyazawa , Jian Wu

We study the boundary stabilization of one-dimensional cross-diffusion systems in a moving domain. We show first exponential stabilization and then finite-time stabilization in arbitrary small-time of the linearized system around uniform…

偏微分方程分析 · 数学 2023-07-14 Jean Cauvin-Vila , Virginie Ehrlacher , Amaury Hayat

To understand the long-run behavior of Markov population models, the computation of the stationary distribution is often a crucial part. We propose a truncation-based approximation that employs a state-space lumping scheme, aggregating…

机器学习 · 统计学 2021-05-05 Michael Backenköhler , Luca Bortolussi , Gerrit Großmann , Verena Wolf

Our Recent advancements in stochastic processes have illuminated a paradox associated with the Einstein model of Brownian motion. The model predicts an infinite propagation speed, conflicting with the second law of thermodynamics. The…

偏微分方程分析 · 数学 2024-07-24 Isanka Garli Hevage , Akif Ibraguimov , Zeev Sobol

Direct simulation of biomolecular dynamics in thermal equilibrium is challenging due to the metastable nature of conformation dynamics and the computational cost of molecular dynamics. Biased or enhanced sampling methods may improve the…

化学物理 · 物理学 2015-06-12 Benjamin Trendelkamp-Schroer , Frank Noe

We consider continuous-state branching processes (CB processes) which become extinct almost surely. First, we tackle the problem of describing the stationary measures on $(0,+\infty)$ for such CB processes. We give a representation of the…

概率论 · 数学 2025-04-30 Rongli Liu , Yan-Xia Ren , Ting Yang

We study the effects of stochastic resetting on the Reallocating geometric Brownian motion (RGBM), an established model for resource redistribution relevant to systems such as population dynamics, evolutionary processes, economic activity,…

We investigate the Brownian diffusion of particles in one spatial dimension and in the presence of finite regions within which particles can either evaporate or be reset to a given location. For open boundary conditions, we highlight the…

统计力学 · 物理学 2020-11-04 Gennaro Tucci , Andrea Gambassi , Shamik Gupta , Édgar Roldán

Confined active particles constitute simple, yet realistic, examples of systems that converge into a non-equilibrium steady state. We investigate a run-and-tumble particle in one spatial dimension, trapped by an external potential, with a…

统计力学 · 物理学 2024-04-09 Oded Farago , Naftali R. Smith

In this paper, we study quasi-stationary distributions of nonlinearly perturbed semi-Markov processes in discrete time. This type of distributions is of interest for the analysis of stochastic systems which have finite lifetimes, but are…

概率论 · 数学 2016-04-28 Mikael Petersson

We develop an exactly-solvable three-state discrete-time minimal Brownian ratchet (MBR), where the transition probabilities between states are asymmetric. By solving the master equations we obtain the steady-state probabilities. Generally…

统计力学 · 物理学 2009-11-07 Youngki Lee , Andrew Allison , Derek Abbott , H. Eugene Stanley

A uniform dimensional result for normally reflected Brownian motion (RBM) in a large class of non-smooth domains is established. Exact Hausdorff dimensions for the boundary occupation time and the boundary trace of RBM are given. Extensions…

概率论 · 数学 2007-05-23 Itai Benjamini , Zhen-Qing Chen , Steffen Rohde

We consider n-point sticky Brownian motions: a family of n diffusions that evolve as independent Brownian motions when they are apart, and interact locally so that the set of coincidence times has positive Lebesgue measure with positive…

概率论 · 数学 2020-10-09 Guillaume Barraquand , Mark Rychnovsky

We consider the dynamical evolution of a Brownian particle undergoing stochastic resetting, meaning that after random periods of time it is forced to return to the starting position. The intervals after which the random motion is stopped…

统计力学 · 物理学 2022-07-19 Mattia Radice

Bi-Directional Grid Constrained (BGC) stochastic processes (BGCSPs) constrain the random movement toward the origin steadily more and more, the further they deviate from the origin, rather than all at once imposing reflective barriers, as…

概率论 · 数学 2021-07-28 Aldo Taranto , Ron Addie , Shahjahan Khan

Motivated by subdiffusive motion of bio-molecules observed in living cells we study the stochastic properties of a non-Brownian particle whose motion is governed by either fractional Brownian motion or the fractional Langevin equation and…

统计力学 · 物理学 2016-09-08 Jae-Hyung Jeon , Ralf Metzler

In this work, we consider a finite-state inhomogeneous-time Markov chain whose probabilities of transition from one state to another tend to decrease over time. This can be seen as a cooling of the dynamics of an underlying Markov chain. We…

概率论 · 数学 2017-05-08 Florian Bouguet , Bertrand Cloez