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A common feature of many recent trials evaluating the effects of immunotherapy on survival is that non-proportional hazards can be anticipated at the design stage. This raises the possibility to use a statistical method tailored towards…

应用统计 · 统计学 2021-08-27 Dominic Magirr , José L. Jiménez

Bayesian methods are actively used for parameter identification and uncertainty quantification when solving nonlinear inverse problems with random noise. However, there are only few theoretical results justifying the Bayesian approach.…

统计理论 · 数学 2020-02-04 Vladimir Spokoiny

In health-related experiments, treatment effects can be identified using paired data that consist of pre- and post-treatment measurements. In this framework, sequential testing strategies are widely accepted statistical tools in practice.…

统计方法学 · 统计学 2018-12-24 Li Zou , Albert Vexler , Jihnhee Yu , Hongzhi Wan

The problem of Bayesian filtering and smoothing in nonlinear models with additive noise is an active area of research. Classical Taylor series as well as more recent sigma-point based methods are two well-known strategies to deal with these…

分布式、并行与集群计算 · 计算机科学 2021-02-02 Fatemeh Yaghoobi , Adrien Corenflos , Sakira Hassan , Simo Särkkä

Scientific researchers utilize randomized experiments to draw casual statements. Most early studies as well as current work on experiments with sequential intervention decisions has been focusing on estimating the causal effects among…

统计方法学 · 统计学 2022-07-27 Jingying Zeng

Laparoscopy is an operation carried out in the abdomen or pelvis through small incisions with external visual control by a camera. This technique needs the abdomen to be insufflated with carbon dioxide to obtain a working space for surgical…

应用统计 · 统计学 2023-10-06 Gabriel Calvo , Carmen Armero , Virgilio Gómez-Rubio , Guido Mazzinari

One of the most popular methodologies for estimating the average treatment effect at the threshold in a regression discontinuity design is local linear regression (LLR), which places larger weight on units closer to the threshold. We…

统计方法学 · 统计学 2019-02-01 Zach Branson , Maxime Rischard , Luke Bornn , Luke Miratrix

In this paper we present a method for the estimation of leaks in non-invasive ventilation. Accurate estimation of leaks is a key component of a ventilator, since it determines the ventilator performance in terms of patient-ventilator…

医学物理 · 物理学 2021-08-19 Francesco Vicario , Samiya Alkhairy , Roberto Buizza , William A. Truschel

We consider a prior for nonparametric Bayesian estimation which uses finite random series with a random number of terms. The prior is constructed through distributions on the number of basis functions and the associated coefficients. We…

统计理论 · 数学 2015-02-10 Weining Shen , Subhashis Ghosal

Datasets containing large samples of time-to-event data arising from several small heterogeneous groups are commonly encountered in statistics. This presents problems as they cannot be pooled directly due to their heterogeneity or analyzed…

机器学习 · 统计学 2016-12-05 Alexandre Piché , Russell Steele , Ian Shrier , Stephanie Long

Heterogeneous treatment effect estimation is critical in oncology, particularly in multi-arm trials with overlapping therapeutic components and long-term survivors. These shared mechanisms pose a central challenge to identifying causal…

统计方法学 · 统计学 2025-10-29 Peter Chang , John Kairalla , Arkaprava Roy

Polymer gels behave as soft viscoelastic solids and exhibit a generic nonlinear mechanical response characterized by pronounced stiffening prior to irreversible failure, most often through macroscopic fractures. Here, we aim at capturing…

软凝聚态物质 · 物理学 2020-08-10 Bavand Keshavarz , Thibaut Divoux , Sébastien Manneville , Gareth H. McKinley

The meta-analysis's utility is dependent on previous studies having accurately captured the variables of interest, but in medical studies, a key decision variable that impacts a physician's decisions was not captured. This results in an…

机器学习 · 计算机科学 2026-01-16 Ashley Klein , Edward Raff , Marcia DesJardin

This work presents an algorithm for determining the parameters of a nonlinear dynamic model of the respiratory system in patients undergoing assisted ventilation. Using the pressure and flow signals measured at the mouth, the model's…

系统与控制 · 电气工程与系统科学 2024-03-01 Diego A. Riva , Carolina A. Evangelista , Paul F. Puleston , Luis Corsiglia , Nahuel Dargains

We develop a nonparametric Bayesian modeling framework for clustered ordinal responses in developmental toxicity studies, which typically exhibit extensive heterogeneity. The primary focus of these studies is to examine the dose-response…

统计方法学 · 统计学 2024-08-22 Jizhou Kang , Athanasios Kottas

We study model near-critical polymer gelling systems made of gluten proteins dispersions stabilized at different distances from the gel point. We impose different shear rates and follow the time evolution of the stress. For sufficiently…

软凝聚态物质 · 物理学 2024-07-18 Ameur Louhichi , Marie-Hélène Morel , Laurence Ramos , Amélie Banc

This paper is devoted to the analysis of non-negative solutions for a generalisation of the classical parabolic-elliptic Patlak-Keller-Segel system with $d\ge3$ and porous medium-like non-linear diffusion. Here, the non-linear diffusion is…

偏微分方程分析 · 数学 2008-01-16 Adrien Blanchet , José Antonio Carrillo , Philippe Laurençot

In recent medical studies, the combination of longitudinal measurements with time-to-event data has increased the demand for more sophisticated models without unbiased estimates. Joint models for longitudinal and survival data have been…

统计方法学 · 统计学 2025-08-01 Dionisio Silva Neto , Denis Rustand , Haavard Rue , Danilo Alvares , Vera L. Tomazella

Bayesian inference and the use of posterior or posterior predictive probabilities for decision making have become increasingly popular in clinical trials. The current practice in Bayesian clinical trials relies on a hybrid…

统计方法学 · 统计学 2024-04-30 Shirin Golchi , James Willard

Nonresponse weighting adjustment using the response propensity score is a popular tool for handling unit nonresponse. Statistical inference after the nonresponse weighting adjustment is complicated because the effect of estimating the…

统计方法学 · 统计学 2017-02-14 Hejian Sang , Jae Kwang Kim
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