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Genetic information is encoded in a linear sequence of nucleotides, represented by letters ranging from thousands to billions. Mutations refer to changes in the DNA or RNA nucleotide sequence. Thus, mutation detection is vital in all areas…

We present a prototype of a software tool for exploration of multiple combinatorial optimisation problems in large real-world and synthetic complex networks. Our tool, called GraphCombEx (an acronym of Graph Combinatorial Explorer),…

社会与信息网络 · 计算机科学 2018-05-15 David Chalupa , Ken A Hawick

Artificial intelligence is constantly evolving and can provide effective help in all aspects of people's lives. The experiment is mainly to study the use of artificial intelligence in the field of medicine. The purpose of this experiment…

图像与视频处理 · 电气工程与系统科学 2023-08-08 Jiuqi Yan

Even though numerous researchers require stable datasets along with source code and basic metrics calculated on them, neither GitHub nor any other code hosting platform provides such a resource. Consequently, each researcher must download…

软件工程 · 计算机科学 2024-03-14 Yegor Bugayenko

The semantic segmentation task in pathology plays an indispensable role in assisting physicians in determining the condition of tissue lesions. With the proposal of Segment Anything Model (SAM), more and more foundation models have seen…

图像与视频处理 · 电气工程与系统科学 2024-09-05 Mingya Zhang , Liang Wang , Zhihao Chen , Yiyuan Ge , Xianping Tao

Medical image processing usually requires a model trained with carefully crafted datasets due to unique image characteristics and domain-specific challenges, especially in pathology. Primitive detection and segmentation in digitized tissue…

计算机视觉与模式识别 · 计算机科学 2024-10-10 Abu Bakor Hayat Arnob , Xiangxue Wang , Yiping Jiao , Xiao Gan , Wenlong Ming , Jun Xu

Machine learning is revolutionizing image-based diagnostics in pathology and radiology. ML models have shown promising results in research settings, but their lack of interoperability has been a major barrier for clinical integration and…

We propose a new model-based computer-aided diagnosis (CAD) system for tumor detection and classification (cancerous v.s. benign) in breast images. Specifically, we show that (x-ray, ultrasound and MRI) images can be accurately modeled by…

人工智能 · 计算机科学 2009-06-22 Nidhal Bouaynaya , Jerzy Zielinski , Dan Schonfeld

We propose a novel approach to cervical cell image classification for cervical cancer screening using the EVA-02 transformer model. We developed a four-step pipeline: fine-tuning EVA-02, feature extraction, selecting important features…

计算机视觉与模式识别 · 计算机科学 2025-05-01 Khoa Tuan Nguyen , Ho-min Park , Gaeun Oh , Joris Vankerschaver , Wesley De Neve

Accurate prediction of cancer type and primary tumor site is critical for effective diagnosis, personalized treatment, and improved outcomes. Traditional models struggle with the complexity of genomic and clinical data, but quantum…

定量方法 · 定量生物学 2025-06-30 Don Roosan , Rubayat Khan , Md Rahatul Ashakin , Tiffany Khou , Saif Nirzhor , Mohammad Rifat Haider

Skin cancer is a global health concern, necessitating early and accurate diagnosis for improved patient outcomes. This study introduces a groundbreaking approach to skin cancer classification, employing the Vision Transformer, a…

图像与视频处理 · 电气工程与系统科学 2024-01-11 Galib Muhammad Shahriar Himel , Md. Masudul Islam , Kh Abdullah Al-Aff , Shams Ibne Karim , Md. Kabir Uddin Sikder

Graphical models are powerful tools to investigate complex dependency structures in high-throughput datasets. However, most existing graphical models make one of the two canonical assumptions: (i) a homogeneous graph with a common network…

统计方法学 · 统计学 2023-10-31 Tsung-Hung Yao , Yang Ni , Anindya Bhadra , Jian Kang , Veerabhadran Baladandayuthapani

Deconvolution of cell mixtures in "bulk" transcriptomic samples from homogenate human tissue is important for understanding the pathologies of diseases. However, several experimental and computational challenges remain in developing and…

Cancer is a disease driven by random DNA mutations and the interaction of many complex phenomena. To improve the understanding and ultimately find more effective treatments, researchers leverage computer simulations mimicking the tumor…

计算物理 · 物理学 2024-01-26 Tobias Duswald , Ernesto A. B. F. Lima , J. Tinsley Oden , Barbara Wohlmuth

Copy number variations in cancer cells and volatility fluctuations in stock prices are commonly manifested as changepoints occurring at the same positions across related data sequences. We introduce a Bayesian modeling framework, BASIC,…

统计方法学 · 统计学 2017-04-17 Zhou Fan , Lester Mackey

With the popularity of Android growing exponentially, the amount of malware has significantly exploded. It is arguably one of the most viral problems on mobile platforms. Recently, various approaches have been introduced to detect Android…

密码学与安全 · 计算机科学 2022-01-25 Peng Xu

The increasing availability of sequencing data of cancer samples is fueling the development of algorithmic strategies to investigate tumor heterogeneity and infer reliable models of cancer evolution. We here build up on previous works on…

Can a single label-free image reveal whether cancer cells were exposed to chemotherapy? We present an innovative methodology on the label-free and high-resolution imaging properties of phase holotomographic microscopy coupled with neural…

Heterogeneous computers integrate general-purpose host processors with domain-specific accelerators to combine versatility with efficiency and high performance. To realize the full potential of heterogeneous computers, however, many…

分布式、并行与集群计算 · 计算机科学 2022-01-12 Andreas Kurth , Björn Forsberg , Luca Benini

Cancers are characterized by remarkable heterogeneity and diverse prognosis. Accurate cancer classification is essential for patient stratification and clinical decision-making. Although digital pathology has been advancing cancer diagnosis…

计算机视觉与模式识别 · 计算机科学 2025-02-13 Xiaofei Wang , Hanyu Liu , Yupei Zhang , Boyang Zhao , Hao Duan , Wanming Hu , Yonggao Mou , Stephen Price , Chao Li