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In chemotaxis, cells are modulating their migration patterns in response to concentration gradients of a guiding substance. Immune cells are believed to use such chemotactic sensing for remotely detecting and homing in on pathogens.…

细胞行为 · 定量生物学 2019-02-28 Claus Metzner

We propose a neural network approach to model general interaction dynamics and an adjoint based stochastic gradient descent algorithm to calibrate its parameters. The parameter calibration problem is considered as optimal control problem…

最优化与控制 · 数学 2021-02-01 Simone Göttlich , Claudia Totzeck

Neural networks have been increasingly employed in Model Predictive Controller (MPC) to control nonlinear dynamic systems. However, MPC still poses a problem that an achievable update rate is insufficient to cope with model uncertainty and…

机器人学 · 计算机科学 2022-07-15 Taekyung Kim , Hojin Lee , Seongil Hong , Wonsuk Lee

Learning to perform perfect tracking tasks based on measurement data is desirable in the controller design of systems operating repetitively. This motivates the present paper to seek an optimization-based design approach for iterative…

系统与控制 · 电气工程与系统科学 2019-08-08 Deyuan Meng , Jingyao Zhang

In this paper, we present a flexible and probabilistic framework for tracking topological features in time-varying scalar fields using merge trees and partial optimal transport. Merge trees are topological descriptors that record the…

计算几何 · 计算机科学 2025-08-26 Mingzhe Li , Xinyuan Yan , Lin Yan , Tom Needham , Bei Wang

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

细胞行为 · 定量生物学 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

Stem cell regeneration is a vital biological process in self-renewing tissues, governing development and tissue homeostasis. Gene regulatory network dynamics are pivotal in controlling stem cell regeneration and cell type transitions.…

分子网络 · 定量生物学 2024-04-19 Yakun Li , Xiyin Liang , Jinzhi Lei

Adaptive tracking control for rigid body dynamics is of critical importance in control and robotics, particularly for addressing uncertainties or variations in system model parameters. However, most existing adaptive control methods are…

机器人学 · 计算机科学 2025-02-11 Jiawei Tang , Shilei Li , Ling Shi

Multi-agent target tracking in the presence of nonlinear dynamics and agent heterogeneity, where state-space dimensions may differ, is a challenging problem that traditional graph Laplacian methods cannot easily address. This work leverages…

系统与控制 · 电气工程与系统科学 2026-01-01 Tyler Hanks , Cristian F. Nino , Joana Bou Barcelo , Austin Copeland , Warren Dixon , James Fairbanks

The joint optimisation of body-plan and control via evolutionary processes can be challenging in rich morphological spaces in which offspring can have body-plans that are very different from either of their parents. This causes a potential…

Despite the rise of billion-parameter foundation models trained across thousands of GPUs, similar scaling gains have not been shown for humanoid control. Current neural controllers for humanoids remain modest in size, target a limited set…

Tracking cells and detecting mitotic events in time-lapse microscopy image sequences is a crucial task in biomedical research. However, it remains highly challenging due to dividing objects, low signal-tonoise ratios, indistinct boundaries,…

计算机视觉与模式识别 · 计算机科学 2025-09-15 Zhu Chen , Mert Edgü , Er Jin , Johannes Stegmaier

The ability to track the optimum of dynamic environments is important in many practical applications. In this paper, the capability of a hybrid genetic algorithm (HGA) to track the optimum in some dynamic environments is investigated for…

神经与进化计算 · 计算机科学 2013-08-27 Quan Yuan , Zhixin Yang

In this work, we present a method for tracking and learning the dynamics of all objects in a large scale robot environment. A mobile robot patrols the environment and visits the different locations one by one. Movable objects are discovered…

机器人学 · 计算机科学 2018-01-30 Nils Bore , Patric Jensfelt , John Folkesson

The links between optimal control of dynamical systems and neural networks have proved beneficial both from a theoretical and from a practical point of view. Several researchers have exploited these links to investigate the stability of…

最优化与控制 · 数学 2019-02-08 Panos Parpas , Corey Muir

Accurate tracking of planned trajectories in the presence of perturbations is an important problem in control and robotics. Symmetry is a fundamental mathematical feature of many dynamical systems and exploiting this property offers the…

系统与控制 · 电气工程与系统科学 2023-08-08 Matthew Hampsey , Pieter van Goor , Robert Mahony

Solving optimal control problems to determine a stabilizing controller involves a significant computational effort. Time-varying optimal control provides a remedy by designing a tracking system, given as an ordinary differential equation,…

系统与控制 · 电气工程与系统科学 2026-04-16 Patrick Schmidt , Stefan Streif

A theoretical framework and numerical techniques to solve optimal control problems with a spatial trace term in the terminal cost and governed by regularized nonlinear hyperbolic conservation laws are provided. Depending on the spatial…

最优化与控制 · 数学 2018-01-23 Sébastien Court , Karl Kunisch , Laurent Pfeiffer

Complex systems' modeling and simulation are powerful ways to investigate a multitude of natural phenomena providing extended knowledge on their structure and behavior. However, enhanced modeling and simulation require integration of…

In this paper, we develop an optimal control framework for dynamical systems when only an approximate model of the underlying plant is available. We consider a setting in which the control strategy is synthesized using a model-based optimal…

最优化与控制 · 数学 2026-01-16 Andreas A. Malikopoulos