相关论文: Adaptive motion mapping in pancreatic SBRT patient…
Imaging demonstrates that preclinical and human tumors are heterogeneous, i.e. a single tumor can exhibit multiple regions that behave differently during both normal development and also in response to treatment. The large variations…
Due to the inter- and intra- variation of respiratory motion, it is highly desired to provide real-time volumetric images during the treatment delivery of lung stereotactic body radiation therapy (SBRT) for accurate and active motion…
Radiation therapy presents a need for dynamic tracking of a target tumor volume. Fiducial markers such as implanted gold seeds have been used to gate radiation delivery but the markers are invasive and gating significantly increases…
Respiratory motion and the associated deformations of abdominal organs and tumors are essential information in clinical applications. However, inter- and intra-patient multi-organ deformations are complex and have not been statistically…
Precise patient positioning is fundamental to successful removal of malignant tumors during treatment of head and neck cancers. Errors in patient positioning have been known to damage critical organs and cause complications. To better…
Current surgical procedures for spinal cord tumors lack in vivo high-resolution, high-speed multifunctional imaging systems, posing challenges for precise tumor resection and intraoperative decision-making. This study introduces the Fast…
Techniques for preclinical intensity modulated radiation therapy are being developed to improve translation by replicating the clinical paradigm. This study presents the first treatment planning comparison between small animal IMRT…
Cone-beam CT (CBCT) provides on-board volumetric anatomy for image guidance and treatment adaptation in radiotherapy. To compensate for respiration-induced anatomical motion, time-resolved CBCT is highly desired to capture the…
The inherent characteristics of lung tissues, which are independent of breathing manoeuvre, may provide fundamental information on lung function. This paper attempted to study function-correlated lung textures and their spatial distribution…
Cone Beam CT (CBCT) plays a crucial role in Adaptive Radiation Therapy (ART) by accurately providing radiation treatment when organ anatomy changes occur. However, CBCT images suffer from scatter noise and artifacts, making relying solely…
Automated segmentation of esophagus is critical in image guided/adaptive radiotherapy of lung cancer to minimize radiation-induced toxicities such as acute esophagitis. We developed a semantic physics-based data augmentation method for…
Time-resolved CBCT imaging, which reconstructs a dynamic sequence of CBCTs reflecting intra-scan motion (one CBCT per x-ray projection without phase sorting or binning), is highly desired for regular and irregular motion characterization,…
Non-small cell lung cancer (NSCLC) is often intrinsically resistant to several first- and second-line therapeutics and can rapidly acquire further resistance after a patient begins receiving treatment. Treatment outcomes are therefore…
Daily or weekly cone-beam computed tomography (CBCT) is employed in image-guided radiotherapy (IGRT) for precise patient alignment. However, its clinical utility in quantitative tasks is hindered by severe artifacts and inaccurate Hounsfeld…
In this work we explored the use of patient specific reinforced learning to generate 3D activity maps from two 2D planar images (anterior and posterior). The solution of this problem remains unachievable using conventional methodologies and…
Radiation therapy (RT) requires precise dose delivery over multiple fractions, with CT fundamental for treatment planning due to its electron density information. Repeated CT acquisitions impose radiation exposure and logistical burdens,…
Purpose: The presence of respiratory motion during radiation treatment leads to degradation of the expected dose distribution, both for target coverage and healthy-tissue sparing, particularly for techniques like pencil-beam scanning proton…
Particle physics simulations are the cornerstone of nuclear engineering applications. Among them radiotherapy (RT) is crucial for society, with 50% of cancer patients receiving radiation treatments. For the most precise targeting of tumors,…
Forecasting motion of a specific target object is a common problem for surgical interventions, e.g. for localization of a target region, guidance for surgical interventions, or motion compensation. Optical coherence tomography (OCT) is an…
Introduction: Lung cancer is a leading cause of cancer-related mortality, and stereotactic body radiotherapy (SBRT) has become a standard treatment for early-stage lung cancer. However, the heterogeneous response to radiation at the tumor…