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Integrating cross-department multi-modal data (e.g., radiological, pathological, genomic, and clinical data) is ubiquitous in brain cancer diagnosis and survival prediction. To date, such an integration is typically conducted by human…

Background: This study examines cardiometabolic (CM) risk factors in an urban South Asian population, integrating medical and Anthropological perspectives to explore the effects of socio-economic, lifestyle, gender-specific factors, and…

定量方法 · 定量生物学 2024-12-11 Karishma Yasmin

Breast cancer is the most common cancer among Western women. Fortunately, organized screening has reduced breast cancer mortality and, consequently, the European Union has recommended screening with mammography for 50-69-year-old women.…

Survival analysis is a statistical framework for modeling time-to-event data, particularly valuable in healthcare for predicting outcomes like patient discharge or recurrence. This study implements and compares several survival models -…

Breast cancer is one of the most threatening diseases in women's life; thus, the early and accurate diagnosis plays a key role in reducing the risk of death in a patient's life. Mammography stands as the reference technique for breast…

机器学习 · 计算机科学 2023-05-05 Juan Zuluaga-Gomez

Background: Lung cancer was known as primary cancers and the survival rate of cancer is about 15%. Early detection of lung cancer is the leading factor in survival rate. All symptoms (features) of lung cancer do not appear until the cancer…

人工智能 · 计算机科学 2016-01-26 Mitra Montazeri , Mahdieh Soleymani Baghshah , Ahmad Enhesari

The influence of per capita income on life expectancy is well documented, mostly through studies of multinational samples. However, one expects fairly weak correlations at both ends of the life span, that is to say in early infancy and in…

物理与社会 · 物理学 2021-09-22 Peter Richmond , Wonguk Cho , Beom Jun Kim , Bertrand M. Roehner

Chronic diseases and cancer account for over 75 percent of healthcare costs in the US. Increased prevention services and improved primary care are thought to decrease costs. Current models for detecting changes in the health of populations…

种群与进化 · 定量生物学 2013-07-15 Jacob Kuriyan , Nathaniel Cobb

It is highly important for governments and health organizations to monitor the prevalence of breast cancer as a leading source of cancer-related death among women. However, the accurate diagnosis of this disease is expensive, especially in…

统计方法学 · 统计学 2021-04-21 M. Mahdizadeha , Ehsan Zamanzade

Over the past decades, both critical care and cancer care have improved substantially. Due to increased cancer-specific survival, we hypothesized that both the number of cancer patients admitted to the ICU and overall survival have…

定量方法 · 定量生物学 2018-08-09 Chris Sauer , Jinghui Dong , Leo Celi , Daniele Ramazzotti

Lung cancer remains a leading cause of cancer-related deaths globally, with non-small cell lung cancer (NSCLC) being the most common subtype. This study aimed to identify key biomarkers associated with stage III NSCLC in non-smoking females…

基因组学 · 定量生物学 2024-09-02 Huili Zheng , Qimin Zhang , Yiru Gong , Zheyan Liu , Shaohan Chen

Time elapsed till an event of interest is often modeled using the survival analysis methodology, which estimates a survival score based on the input features. There is a resurgence of interest in developing more accurate prediction models…

机器学习 · 计算机科学 2024-07-23 Navid Seidi , Ardhendu Tripathy , Sajal K. Das

The Health and Retirement Study is a longitudinal study of US adults enrolled at age 50 and older. We were interested in investigating the effect of a sudden large decline in wealth on the cognitive score of subjects. Our analysis was…

We conducted a prospective analysis of incident dementia and its association with 65 sociodemographic, early-life, economic, health and behavioral, social, and genetic risk factors in a sample of 7,908 adults over the age of 50 from the…

应用统计 · 统计学 2021-01-27 Jordan Weiss , Eli Puterman , Aric A. Prather , Erin B. Ware , David H. Rehkopf

Breast cancer has been reported to account for the maximum cases among all female cancers till date. In order to gain a deeper insight into the complexities of the disease, we analyze the breast cancer network and its normal counterpart at…

分子网络 · 定量生物学 2017-04-05 Aparna Rai , A. Vipin Menon , Sarika Jalan

Colorectal cancer refers to the cancer from the dentate line to the junction of rectosigmoid colon, which is one of the most common malignant tumors of the digestive tract. The treatment of colorectal cancer is controversial, so…

其他定量生物学 · 定量生物学 2022-02-09 Boda Xie

While death rates due to diseases of the heart have experienced a sharp decline over the past 50 years, these diseases continue to be the leading cause of death in the United States, and the rate of decline varies by geographic location,…

统计方法学 · 统计学 2018-01-23 Harrison Quick , Lance A. Waller , Michele Casper

Neural networks are capable of learning rich, nonlinear feature representations shown to be beneficial in many predictive tasks. In this work, we use these models to explore the use of geographical features in predicting colorectal cancer…

机器学习 · 计算机科学 2017-08-17 Michael T. Lash , Yuqi Sun , Xun Zhou , Charles F. Lynch , W. Nick Street

In early-phase cancer clinical trials, the limited availability of data presents significant challenges in developing a framework to efficiently quantify treatment effectiveness. To address this, we propose a novel utility-based Bayesian…

统计方法学 · 统计学 2025-06-10 Saurabh Bhandari , Michael J. Daniels , Chenguang Wang

Will the United Kingdom's ageing population be fit and independent, or suffer from greater chronic ill health? Healthy life expectancy is commonly used to assess this: it is an estimate of how many years are lived in good health over the…

统计理论 · 数学 2007-06-13 Ehsan Khoman , Martin Weale