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We present a novel model to estimate biological effects caused by artificial radiation exposure, Whack-a-mole (WAM) model. It is important to take account of the recovery effects during the time course of the cellular reactions. The…

We propose LD(Low Dose) model, the extension of LDM model which was proposed in the previous paper [Y. Manabe et al.: J. Phys. Soc. Jpn. 81 (2012) 104004] to estimate biological damage caused by irradiation. LD model takes account of all…

生物物理 · 物理学 2015-06-05 Yuichiro Manabe , Masako Bando

We develop a kinetic reaction model for cells having irradiated DNA molecules due to ionizing radiation exposure. Our theory simultaneously accounts for the time-dependent reactions of the DNA damage, the DNA mutation, the DNA repair, and…

生物物理 · 物理学 2015-06-18 Yuichiro Manabe , Issei Nakamura , Masako Bando

The dependent scattering effect (DSE), which arises from the wave nature of electromagnetic radiation, is a critical mechanism affecting the radiative properties of micro/nanoscale discrete disordered media (DDM). In the last a few decades,…

介观与纳米尺度物理 · 物理学 2020-09-01 B. X. Wang , C. Y. Zhao

Accurate dose distribution prediction is crucial in the radiotherapy planning. Although previous methods based on convolutional neural network have shown promising performance, they have the problem of over-smoothing, leading to prediction…

图像与视频处理 · 电气工程与系统科学 2024-10-31 Xin Liao , Zhenghao Feng , Jianghong Xiao , Xingchen Peng , Yan Wang

The approximate nature of radiative transfer equation (RTE) leads to a bunch of considerations on the effect of "dependent scattering" in random media, especially particulate media composed of discrete scatterers, in the last a few decades,…

介观与纳米尺度物理 · 物理学 2018-05-08 B. X. Wang , C. Y. Zhao

If dark matter is composed of weakly interacting particles, Earth's orbital motion may induce a small annual variation in the rate at which these particles interact in a terrestrial detector. The DAMA collaboration has identified at a…

高能物理 - 唯象学 · 物理学 2018-11-29 Chris Kelso , Christopher Savage , Pearl Sandick , Katherine Freese , Paolo Gondolo

The change in materials properties subjected to irradiation by highly energetic particles strongly depends on the irradiation dose rate. Atomistic simulations can in principle be used to predict microstructural evolution where experimental…

材料科学 · 物理学 2025-06-24 Max Boleininger , Daniel R. Mason , Thomas Schwarz-Selinger , Pui-Wai Ma

Here we present a semiclassical analysis of spontaneous and stimulated radiative emission from unmodulated and optically-modulated electron quantum wavepackets. We show that the radiative emission/absorption and corresponding…

量子物理 · 物理学 2018-11-28 Yiming Pan , Avraham Gover

We study the environmental dependence of ultralight scalar dark matter (DM) with linear interactions to the standard model particles. The solution to the DM field turns out to be a sum of the cosmic harmonic oscillation term and the local…

原子物理 · 物理学 2022-05-03 Wei Zhao , Dongfeng Gao , Jin Wang , Mingsheng Zhan

We propose Radiation Exposure Theory (RET), a mathematical framework to estimate biological damage caused by irradiation. This is an extension of LDM model which was proposed in the paper [Y. Manabe et al.: J. Phys. Soc. Jpn. 81,…

生物物理 · 物理学 2014-11-18 Yuichiro Manabe , Masako Bando

Starting from a general equation for organism (or cell system) growth and attributing additional cell death rate (besides the natural rate) to therapy, we derive an equation for cell response to {\alpha} radiation. Different from previous…

医学物理 · 物理学 2012-07-20 L. J. Liu

The dependent scattering mechanism is known to have a significant impact on the radiative properties of random media containing discrete scatterers. Here we theoretically demonstrate the role of dependent scattering on the radiative…

介观与纳米尺度物理 · 物理学 2018-07-26 B. X. Wang , C. Y. Zhao

The manifestation of measurements, randomly distributed in time, on the evolution of quantum systems are analyzed in detail. The set of randomly distributed measurements (RDM) is modeled within the renewal theory, in which the distribution…

量子物理 · 物理学 2015-05-20 A. I. Shushin

Ion-induced cell killing has been reported to depend on the irradiation dose but also on the projectile parameters. In this paper we focus on two approaches developed and extensively used to predict cell survival in response to ion…

生物物理 · 物理学 2009-07-15 M. Beuve , A. Colliaux , D. Dabli , D. Dauvergne , B. Gervais , G. Montarou , E. Testa

We propose a mathematical model for estimating biological damage caused by low-dose irradiation. We understand that the Linear Non Threshold (LNT) hypothesis is realized only in the case of no recovery effects. In order to treat the…

生物物理 · 物理学 2012-10-08 Yuichiro Manabe , Kento Ichikawa , Masako Bando

Giant atoms are known for the frequency-dependent spontaneous emission and associated interference effects. In this paper, we study the spontaneous emission dynamics of a two-level giant atom with dynamically modulated transition frequency.…

量子物理 · 物理学 2022-11-28 Lei Du , Yan Zhang , Yong Li

The pattern of radiation energy deposition in substances at the microscopic level of lattice, molecule size, or the cell's nucleus is not uniform. The energy of radiation is transferred to the substance medium in the form of discrete,…

医学物理 · 物理学 2022-10-14 Elsayed K. Elmaghraby , Mohamed Bahaaeldin-Afifi

In randomized dose-finding trials, although drug exposure data form a part of key information for dose selection, the evaluation of the dose-response (DR) relationship often mainly uses DR data. We examine the benefit of…

统计方法学 · 统计学 2025-08-07 Jixian Wang , Zhiwei Zhang , Ram Tiwari

Radiotherapy treatment planning often relies on time-consuming, trial-and-error adjustments that heavily depend on the expertise of specialists, while existing deep learning methods face limitations in generalization, prediction accuracy,…

计算机视觉与模式识别 · 计算机科学 2026-01-06 Hui Xie , Haiqin Hu , Lijuan Ding , Qing Li , Yue Sun , Tao Tan
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