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Diet is a risk factor for many diseases. In nutritional epidemiology, studying reproducible dietary patterns is critical to reveal important associations with health. However, it is challenging: diverse cultural and ethnic backgrounds may…

应用统计 · 统计学 2025-02-10 Roberta De Vito , Alejandra Avalos-Pacheco

Data analysis is a powerful tool in all experimental sciences. Statistical methods, such as sampling theory, computer technologies necessary for handling large amounts of data, skill in analysing information contained in different types of…

物理教育 · 物理学 2012-06-20 Vera Montalbano

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

计算机视觉与模式识别 · 计算机科学 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

One primary task of population health analysis is the identification of risk factors that, for some subpopulation, have a significant association with some health condition. Examples include finding lifestyle factors associated with chronic…

机器学习 · 计算机科学 2018-11-29 Alexander New , Sabbir M. Rashid , John S. Erickson , Deborah L. McGuinness , Kristin P. Bennett

Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes…

The modern science of networks has brought significant advances to our understanding of complex systems. One of the most relevant features of graphs representing real systems is community structure, or clustering, i. e. the organization of…

物理与社会 · 物理学 2010-09-17 Santo Fortunato

Investigations of infectious disease outbreaks often focus on identifying place- and context-dependent factors responsible for emergence and spread, resulting in phenomenological narratives ill-suited to developing generalizable predictive…

The complexity of exploratory data analysis poses significant challenges for collaboration and effective communication of analytic workflows. Automated methods can alleviate these challenges by summarizing workflows into more interpretable…

人机交互 · 计算机科学 2024-10-16 Shaghayegh Esmaeili , Irelis D. Suarez , Ezekiel Ajayi , Eric D. Ragan

Many Artificial Intelligence systems depend on the agent's updating its beliefs about the world on the basis of experience. Experiments constitute one type of experience, so scientific methodology offers a natural environment for examining…

人工智能 · 计算机科学 2013-04-08 Harold P. Lehmann

Inferring causal effects from an observational study is challenging because participants are not randomized to treatment. Observational studies in infectious disease research present the additional challenge that one participant's treatment…

统计方法学 · 统计学 2020-12-25 Brian G. Barkley , Michael G. Hudgens , John D. Clemens , Mohammad Ali , Michael E. Emch

We consider methods for causal inference in randomized trials nested within cohorts of trial-eligible individuals, including those who are not randomized. We show how baseline covariate data from the entire cohort, and treatment and outcome…

统计方法学 · 统计学 2019-10-30 Issa Dahabreh , Sarah Robertson , Eric Tchetgen Tchetgen , Elizabeth Stuart , Miguel Hernan

Healthcare professionals have long envisioned using the enormous processing powers of computers to discover new facts and medical knowledge locked inside electronic health records. These vast medical archives contain time-resolved…

机器学习 · 计算机科学 2020-05-15 Ahmed Allam , Matthias Dittberner , Anna Sintsova , Dominique Brodbeck , Michael Krauthammer

Visualisation facilitates the understanding of scientific data both through exploration and explanation of visualised data. Provenance contributes to the understanding of data by containing the contributing factors behind a result. With the…

数据库 · 计算机科学 2015-02-06 Bilal Arshad , Kamran Munir , Richard McClatchey , Saad Liaquat

Cell state discovery is crucial for understanding biological systems and enhancing medical outcomes. A key aspect of this process is identifying distinct biomarkers that define specific cell states. However, difficulties arise from the…

人机交互 · 计算机科学 2025-12-19 Rui Sheng , Zelin Zang , Jiachen Wang , Yan Luo , Zixin Chen , Yan Zhou , Shaolun Ruan , Huamin Qu

Graphs are used to model interactions in a variety of contexts, and there is a growing need to quickly assess the structure of such graphs. Some of the most useful graph metrics are based on triangles, such as those measuring social…

社会与信息网络 · 计算机科学 2014-10-21 C. Seshadhri , Ali Pinar , Tamara G. Kolda

Since its first formulations almost a century ago, mathematical models for disease spreading contributed to understand, evaluate and control the epidemic processes.They promoted a dramatic change in how epidemiologists thought of the…

适应与自组织系统 · 物理学 2013-12-16 Marcelo N. Kuperman

There is a great concern nowadays regarding alcohol consumption and drug abuse, especially in young people. Analyzing the social environment where these adolescents are immersed, as well as a series of measures determining the alcohol abuse…

Advances in entity-graph based analysis of histopathology images have brought in a new paradigm to describe tissue composition, and learn the tissue structure-to-function relationship. Entity-graphs offer flexible and scalable…

图像与视频处理 · 电气工程与系统科学 2021-07-22 Guillaume Jaume , Pushpak Pati , Valentin Anklin , Antonio Foncubierta , Maria Gabrani

Graphs are very effective tools in visualizing information and are used in many fields including the medical field. In most developing countries primary care, graphs are used to monitor child growth. These measures are therefore often…

计算机与社会 · 计算机科学 2021-08-24 Thea Hvalen Thodesen , Uy Tran , Jens Kaasboll , Chipo Kanjo , Tiwonge Manda

Meta-analysis, by synthesizing effect estimates from multiple studies conducted in diverse settings, stands at the top of the evidence hierarchy in clinical research. Yet, conventional approaches based on fixed- or random-effects models…