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How can we develop simple yet realistic models of the small neural circuits known as central pattern generators (CPGs), which contribute to generate complex multi-phase locomotion in living animals? In this paper we introduce a new model…

神经元与认知 · 定量生物学 2020-09-16 Valentina Baruzzi , Matteo Lodi , Marco Storace , Andrey Shilnikov

Synchronized oscillations in networks of inhibitory and excitatory coupled bursting neurons are common in a variety of neural systems from central pattern generators to human brain circuits. One example of the latter is the subcortical…

神经元与认知 · 定量生物学 2011-09-21 Choongseok Park , Leonid L. Rubchinsky

Inhibitory interneurons, ubiquitous in the central nervous system, form networks connected through both chemical synapses and gap junctions. These networks are essential for regulating the activity of principal neurons, especially by…

神经元与认知 · 定量生物学 2025-05-09 Hélène Todd , Mathieu Desroches , Alex Cayco-Gajic , Boris Gutkin

Bursting neurons fire rapid sequences of action potential spikes followed by a quiescent period. The basic dynamical mechanism of bursting is the slow currents that modulate a fast spiking activity caused by rapid ionic currents. Minimal…

混沌动力学 · 物理学 2015-02-16 Fabiano A. S. Ferrari , Ricardo L. Viana , Sérgio R. Lopes , Ruedi Stoop

We study a network of spiking neurons with heterogeneous excitabilities connected via inhibitory delayed pulses. For globally coupled systems the increase of the inhibitory coupling reduces the number of firing neurons by following a Winner…

无序系统与神经网络 · 物理学 2019-05-29 Stefano Luccioli , David Angulo Garcia , Alessandro Torcini

In many neural networks, patterns controlling rhythmic behaviors are maintained across a wide range of periods. In the crustacean pyloric central pattern generator (CPG), a constant bursting pattern is preserved over a three-to-fivefold…

神经元与认知 · 定量生物学 2025-07-15 Gabrielle O'Brien , Adam L. Weaver , William H. Barnett , Dmitry A. Kozhanov , Gennady S. Cymbalyuk

We propose a novel discrete model of central pattern generators (CPG), neuronal ensembles generating rhythmic activity. The model emphasizes the role of nonsynaptic interactions and the diversity of electrical properties in nervous systems.…

神经与进化计算 · 计算机科学 2017-05-10 Nikolay Bazenkov , Varvara Dyakonova , Oleg Kuznetsov , Dmitri Sakharov , Dmitry Vorontsov , Liudmila Zhilyakova

Entrainment of movement to a periodic stimulus is a characteristic intelligent behaviour in humans and an important goal for adaptive robotics. We demonstrate a quadruped central pattern generator (CPG), consisting of modified Matsuoka…

适应与自组织系统 · 物理学 2022-10-05 Alex Szorkovszky , Frank Veenstra , Kyrre Glette

Animals possess a remarkable ability to navigate challenging terrains, achieved through the interplay of various pathways between the brain, central pattern generators (CPGs) in the spinal cord, and musculoskeletal system. Traditional…

机器人学 · 计算机科学 2024-04-30 Ge Sun , Milad Shafiee , Peizhuo Li , Guillaume Bellegarda , Auke Ijspeert , Guillaume Sartoretti

In this contribution, we have considered the collective behavior of the two as well as the network of heterogeneous coupled Hindmarsh Rose (HR) neurons. The heterogeneous models were made of a memristive 2D (HR) and the traditional 3D HR…

神经元与认知 · 定量生物学 2023-02-24 Zeric Tabekoueng Njitacke , Sishu Shankar Muni , Soumyajit Seth , Jan Awrejcewicz , Jacques Kengne

Neuronal networks are controlled by a combination of the dynamics of individual neurons and the connectivity of the network that links them together. We study a minimal model of the preBotzinger complex, a small neuronal network that…

神经元与认知 · 定量生物学 2013-05-29 David J. Schwab , Robijn F. Bruinsma , Alex J. Levine

We study inhibitory coherence (i.e., collective coherence by synaptic inhibition) in an ensemble of globally-coupled type-I neurons which can fire at arbitrarily low frequencies. No inhibitory coherence is observed in a homogeneous ensemble…

生物物理 · 物理学 2011-11-01 Duk-Geun Hong , Sang-Yoon Kim , Woochang Lim

We study a network model of two conductance-based pacemaker neurons of differing natural frequency, coupled with either mutual excitation or inhibition, and receiving shared random inhibitory synaptic input. The networks may phase-lock…

神经元与认知 · 定量生物学 2009-11-13 Ramana Dodla , Charles J. Wilson

Central Pattern Generators (CPGs) are biological neural circuits capable of producing coordinated rhythmic outputs in the absence of rhythmic input. As a result, they are responsible for most rhythmic motion in living organisms. This…

机器学习 · 计算机科学 2019-01-21 Vincent Liu , Ademi Adeniji , Nathaniel Lee , Jason Zhao , Mario Srouji

Central Pattern Generators (CPGs) in invertebrates are comprised of networks of neurons in which every neuron has reciprocal connections to other members of the CPG. This is a ``closed'' network topology. An ``open'' topology, where one or…

chao-dyn · 物理学 2007-05-23 R. Huerta , P. Varona , M. I. Rabinovich , Henry D. I. Abarbanel

We identify and describe the key qualitative rhythmic states in various 3-cell network motifs of a multifunctional central pattern generator (CPG). Such CPGs are neural microcircuits of cells whose synergetic interactions produce multiple…

混沌动力学 · 物理学 2015-06-18 Jeremy Wojcik , Robert Clewley , Justus Schwabedal , Andrey L. Shilnikov

The synchronization of different $\gamma$-rhythms arising in different brain areas has been implicated in various cognitive functions. Here, we focus on the effect of the ubiquitous neuronal heterogeneity on the synchronization of PING…

神经元与认知 · 定量生物学 2021-09-15 Xize Xu , Hermann Riecke

Many biological neuronal networks exhibit highly variable spiking activity. Balanced networks offer a parsimonious model of this variability. In balanced networks, strong excitatory synaptic inputs are canceled by strong inhibitory inputs…

神经元与认知 · 定量生物学 2016-05-04 Ryan Pyle , Robert Rosenbaum

In this paper, we focus on the emergence of diverse neuronal oscillations arising in a mixed population of neurons with different excitability properties. These properties produce mixed mode oscillations (MMOs) characterized by the…

适应与自组织系统 · 物理学 2020-05-07 Subrata Ghosh , Argha Mondal , Peng Ji , Arindam Mishra , Syamal Kumar Dana , Chris G. Antonopoulos , Chittaranjan Hens

Inhibitory neurons play a crucial role in maintaining persistent neuronal activity. Although connected extensively through electrical synapses (gap-junctions), these neurons also exhibit interactions through chemical synapses in certain…

神经元与认知 · 定量生物学 2021-04-08 R. Janaki , A. S. Vytheeswaran
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