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The interplay between bacterial chromosome organization and functions such as transcription and replication can be studied in increasing detail using novel experimental techniques. Interpreting the resulting quantitative data, however, can…

生物物理 · 物理学 2023-12-18 Janni Harju , Chase P. Broedersz

This paper addresses the decomposition of biochemical networks into functional modules that preserve their dynamic properties upon interconnection with other modules, which permits the inference of network behavior from the properties of…

分子网络 · 定量生物学 2014-12-03 Hari Sivakumar , Stephen R. Proulx , João P. Hespanha

Structured populations are ubiquitous across the biological sciences. Mathematical models of these populations allow us to understand how individual physiological traits drive the overall dynamics in aggregate. For example, linear age- or…

偏微分方程分析 · 数学 2022-04-25 Sabina L. Altus , Jeffrey C. Cameron , David M. Bortz

The interdependence between an individual strategy decision and the resulting change of environmental state is often a subtle process. Feedback-evolving games have been a prevalent framework for studying such feedback in well-mixed…

种群与进化 · 定量生物学 2025-03-05 Qiushuang Wang , Xiaojie Chen , Attila Szolnoki

Social interaction between microbes can be described at many levels of details, ranging from the biochemistry of cell-cell interactions to the ecological dynamics of populations. Choosing the best level to model microbial communities…

种群与进化 · 定量生物学 2020-09-09 Chen Liao , Tong Wang , Sergei Maslov , Joao B. Xavier

Bacteria are highly adaptive microorganisms that thrive in a wide range of growth conditions via changes in cell morphologies and macromolecular composition. How bacterial morphologies are regulated in diverse environmental conditions is a…

细胞行为 · 定量生物学 2021-10-26 Diana Serbanescu , Nikola Ojkic , Shiladitya Banerjee

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

概率论 · 数学 2011-01-21 Sylvie Méléard , Sylvie Roelly

There are numerous scenarios in which populations of cells migrate in crowded environments. Typical examples include wound healing, cancer growth and embryo development. In these crowded environments cells are able to interact with each…

细胞行为 · 定量生物学 2019-07-03 Christian A. Yates , George Chappelle

The dynamics of many microbial ecosystems are driven by cross-feeding interactions, in which metabolites excreted by some species are metabolised further by others. The population dynamics of such ecosystems are governed by…

种群与进化 · 定量生物学 2016-08-16 Björn Vessman , Philip Gerlee , Torbjörn Lundh

Microbial communities play a significant role in bioremediation,plant growth,human and animal digestion,global elemental cycles including the carbon-cycle,and water treatment.They are also posed to be the engines of renewable energy via…

新兴技术 · 计算机科学 2016-01-12 Nicolò Michelusi , James Boedicker , Mohamed Y. El-Naggar , Urbashi Mitra

Cooperation is ubiquitous ranging from multicellular organisms to human societies. Population structures indicating individuals' limited interaction ranges are crucial to understand this issue. But it is still at large to what extend…

生物物理 · 物理学 2014-04-18 Aming Li , Bin Wu , Long Wang

A big challenge in current biology is to understand the exact self-organization mechanism underlying complex multi-physics coupling developmental processes. With multiscale computations of from subcellular gene expressions to cell…

细胞行为 · 定量生物学 2021-05-18 Xiaoliang Wang , Dongyun Bai

Cellular patterns formed by self-organization of dislocations are a most conspicuous feature of dislocation microstructure evolution during plastic deformation. To elucidate the physical mechanisms underlying dislocation cell structure…

材料科学 · 物理学 2020-07-20 Ronghai Wu , Michael Zaiser

The spatiotemporal coordination and regulation of cell proliferation is fundamental in many aspects of development and tissue maintenance. Cells have the ability to adapt their division rates in response to mechanical constraints, yet we do…

定量方法 · 定量生物学 2024-04-25 Carles Falcó , Daniel J. Cohen , José A. Carrillo , Ruth E. Baker

The dynamics of microbial communities is incredibly complex, determined by competition for metabolic substrates and cross-feeding of byproducts. Species in the community grow by harvesting energy from chemical reactions that transform…

种群与进化 · 定量生物学 2022-03-22 Ashish B. George , Tong Wang , Sergei Maslov

An organism that is newly introduced into an existing population has a survival probability that is dependent on both the population density of its environment and the competition it experiences with the members of that population.…

种群与进化 · 定量生物学 2024-12-17 Jason M. Gray , Rowan J. Barker-Clarke , Jacob G. Scott , Michael Hinczewski

Many scientific collaboration networks exhibit clear community and small world structures. However, the studies on the underlying mechanisms for the formation and evolution of community and small world structures are still insufficient. The…

物理与社会 · 物理学 2015-10-28 Peng Liu , Shuangling Luo , Haoxiang Xia

Soil is a complex, dynamic material, with physical properties that depend on its biological content. We propose a cellular automaton model for self-organizing soil structure, where soil aggregates and serves as food for microbial species.…

生物物理 · 物理学 2025-10-10 Riz Fernando Noronha , Kim Sneppen , Kunihiko Kaneko

Microbial biomass carbon (MBC), a crucial soil labile carbon fraction, is the most active component of the soil organic carbon (SOC) that regulates bio-geochemical processes in terrestrial ecosystems. Some studies in the literature ignore…

We explore the emergence of cooperation in the framework of evolutionary game theory. First we introduce the cooperation problem in a novel way that we believe it have important consequences in how problem is addressed. Then we present a…

计算机科学与博弈论 · 计算机科学 2012-08-09 Ignacio Gomez Portillo