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Blood pressure regulation is commonly addressed in terms of local mechanisms such as vascular resistance, compliance and neurohumoral control. However, the human vasculature encompasses multiple quasi-closed flow loops under both…

医学物理 · 物理学 2026-02-11 Arturo Tozzi

Cardiac MRI allows for a comprehensive assessment of myocardial structure, function and tissue characteristics. Here we describe a foundational vision system for cardiac MRI, capable of representing the breadth of human cardiovascular…

Computational modelling is helpful for elucidating the cellular mechanisms driving biological morphogenesis. Previous simulation studies of blood vessel growth based on the Cellular Potts model (CPM) proposed that elongated, adhesive or…

细胞行为 · 定量生物学 2015-09-07 Dimitrios Palachanis , András Szabó , Roeland M. H. Merks

Reduced-order template models are widely used to control high degree-of-freedom legged robots, but existing methods for template-based whole-body control rely heavily on heuristics and often suffer from robustness issues. In this letter, we…

机器人学 · 计算机科学 2020-12-23 Vince Kurtz , Patrick M. Wensing , Hai Lin

Background: How can mathematics help us to understand the mechanism of the cardiac motion? The best known approach is to take a mathematical model of the fibered structure, insert it into a more-or-less complex model of cardiac…

医学物理 · 物理学 2014-06-25 Saeed Ranjbar , Mersedeh Karvandi

Numerical simulations of pulsatile blood flow in an aortic coarctation require the use of turbulence modeling. This paper considers three models from the class of large eddy simulation (LES) models (Smagorinsky, Vreman,…

计算工程、金融与科学 · 计算机科学 2022-09-02 Sarah Katz , Alfonso Caiazzo , Baptiste Moreau , Ulrich Wilbrandt , Jan Brüning , Leonid Goubergrits , Volker John

Biological cells utilize membranes and liquid-like droplets, known as biomolecular condensates, to structure their interior. The interaction of droplets and membranes, despite being involved in several key biological processes, is so far…

软凝聚态物质 · 物理学 2024-02-21 Marcel Mokbel , Dominic Mokbel , Susanne Liese , Christoph A. Weber , Sebastian Aland

A method is proposed to analyze the heartbeat waveform that can yield a reliable characterization of the structure after only a few pulses. The measure suggested is entropy index that is related to the one found effective in describing…

医学物理 · 物理学 2007-05-23 Rudolph C. Hwa

Automatic labelling of anatomical structures, such as coronary arteries, is critical for diagnosis, yet existing (non-deep learning) methods are limited by a reliance on prior topological knowledge of the expected tree-like structures. As…

图像与视频处理 · 电气工程与系统科学 2024-03-05 Yadan Li , Mohammad Ali Armin , Simon Denman , David Ahmedt-Aristizabal

Electrocardiogram (ECG) can be reliably used as a measure to monitor the functionality of the cardiovascular system. Recently, there has been a great attention towards accurate categorization of heartbeats. While there are many…

计算机与社会 · 计算机科学 2018-11-06 Mohammad Kachuee , Shayan Fazeli , Majid Sarrafzadeh

Humans have the amazing ability to perform very subtle manipulation task using a closed-loop control system with imprecise mechanics (i.e., our body parts) but rich sensory information (e.g., vision, tactile, etc.). In the closed-loop…

计算机视觉与模式识别 · 计算机科学 2018-08-07 Tz-Ying Wu , Juan-Ting Lin , Tsun-Hsuang Wang , Chan-Wei Hu , Juan Carlos Niebles , Min Sun

Predictive modeling of blood flow and pressure have numerous applications ranging from non-invasive assessment of functional significance of disease to planning invasive procedures. While several such predictive modeling techniques have…

Arterial blood pressure is a key vital sign for the health of the human body. As such, accurate and reproducible measurement techniques are necessary for successful diagnosis. Blood pressure measurement is an example of molecular…

信息论 · 计算机科学 2014-10-22 Malcolm Egan , Adam Noel , Yansha Deng , Maged Elkashlan , Trung Q. Duong

The topology method is an algorithm for accurate estimation of instantaneous heartbeat intervals using millimeter-wave radar signals. In this model, feature points are extracted from the skin displacement waveforms generated by heartbeats…

信号处理 · 电气工程与系统科学 2024-02-23 Yuji Tanaka , Kimitaka Sumi , Itsuki Iwata , Takuya Sakamoto

In this study, palpating and rolling arteries with different physical properties and tactile distinction of them from each other, using finite element method, are presented. Five models have been created: healthy artery containing blood,…

医学物理 · 物理学 2018-08-14 Ali Abouei Mehrizi , Siamak Najarian , Roozbeh Khodambashi , Salman Dehkhoda

Left ventricular (LV) stiffness and contractility, characterized by the end-diastolic and end-systolic pressure-volume relationships (EDPVR & ESPVR), are two important indicators of the performance of the human heart. Although much research…

医学物理 · 物理学 2023-08-22 Yunxiao Zhang , Moritz Kalhöfer-Köchling , Eberhard Bodenschatz , Yong Wang

In this work, we present mixed dimensional models for simulating blood flow and transport processes in breast tissue and the vascular tree supplying it. These processes are considered, to start from the aortic inlet to the capillaries and…

组织与器官 · 定量生物学 2022-10-10 Marvin Fritz , Tobias Köppl , J. Tinsley Oden , Andreas Wagner , Barbara Wohlmuth , Chengyue Wu

Image-based modeling is essential for understanding cardiovascular hemodynamics and advancing the diagnosis and treatment of cardiovascular diseases. Constructing patient-specific vascular models remains labor-intensive, error-prone, and…

计算机视觉与模式识别 · 计算机科学 2025-03-18 Pan Du , Delin An , Chaoli Wang , Jian-Xun Wang

This paper introduces a constructive method for approximating relative continuum measurements in two-dimensional electrical impedance tomography based on data originating from either the point electrode model or the complete electrode…

数值分析 · 数学 2021-03-09 Henrik Garde , Nuutti Hyvönen

We propose a novel artificial compression, reduced order model (AC-ROM) for the numerical simulation of viscous incompressible fluid flows. The new AC-ROM provides approximations not only for velocity, but also for pressure, which is needed…