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The complex correlation structure of a collection of orthologous DNA sequences is uniquely captured by the "ancestral recombination graph" (ARG), a complete record of coalescence and recombination events in the history of the sample.…

种群与进化 · 定量生物学 2013-12-04 Matthew D. Rasmussen , Melissa J. Hubisz , Ilan Gronau , Adam Siepel

Parental origin effects play an important role in mammal development and disorder. Case-control mother-child pair genotype data can be used to detect parental origin effects and is often convenient to collect in practice. Most existing…

统计方法学 · 统计学 2022-08-11 Yuang Tian , Hong Zhang , Alexandre Bureau , Hagit Hochner , Jinbo Chen

The paper describes a new class of capture-recapture models for closed populations when individual covariates are available. The novelty consists in combining a latent class model for the distribution of the capture history, where the class…

统计方法学 · 统计学 2021-11-08 Antonio Forcina , Francesco Bartolucci

We present a computational approach to solution of the Kiefer-Weiss problem. Algorithms for construction of the optimal sampling plans and evaluation of their performance are proposed. In the particular case of Bernoulli observations, the…

统计方法学 · 统计学 2021-10-12 Andrey Novikov , Andrei Novikov , Fahil Farkhshatov

Composite likelihood provides approximate inference when the full likelihood is intractable and sub-likelihood functions of marginal events can be evaluated relatively easily. It has been successfully applied for many complex models.…

统计方法学 · 统计学 2024-09-05 Wentao Li , Rosabeth White , Dennis Prangle

We use traveling-wave theory to derive expressions for the rate of accumulation of deleterious mutations under Muller's ratchet and the speed of adaptation under positive selection in asexual populations. Traveling-wave theory is a…

种群与进化 · 定量生物学 2007-12-19 Igor M. Rouzine , Eric Brunet , Claus O. Wilke

Count data appears in various disciplines. In this work, a new method to analyze time series count data has been proposed. The method assumes exponentially decaying covariance structure, a special class of the Mat\'ern covariance function,…

统计方法学 · 统计学 2021-02-19 Soudeep Deb

Mathematical models of genetic evolution often come in pairs, connected by a so-called duality relation. The most seminal example are the Wright-Fisher diffusion and the Kingman coalescent, where the former describes the stochastic…

概率论 · 数学 2024-02-02 Jere Koskela , Krzysztof Łatuszyński , Dario Spanò

Modern developments in population dynamics emphasize the role of the turnover of individuals. In the new approaches stable population size is a dynamic equilibrium between different mortality and fecundity factors instead of an arbitrary…

种群与进化 · 定量生物学 2014-03-05 Krzysztof Argasinski , Mark Broom

Many partial identification problems can be characterized by the optimal value of a function over a set where both the function and set need to be estimated by empirical data. Despite some progress for convex problems, statistical inference…

统计方法学 · 统计学 2022-08-31 Matthew Tudball , Rachael Hughes , Kate Tilling , Jack Bowden , Qingyuan Zhao

ABC algorithms are notoriously expensive in computing time, as they require simulating many complete artificial datasets from the model. We advocate in this paper a "divide and conquer" approach to ABC, where we split the likelihood into n…

统计计算 · 统计学 2015-12-02 Simon Barthelmé , Nicolas Chopin , Vincent Cottet

Populations of interest are often hidden from data for a variety of reasons, though their magnitude remains important in determining resource allocation and appropriate policy. One popular approach to population size estimation, the…

统计方法学 · 统计学 2025-06-27 Mallory J Flynn , Paul Gustafson

Kingman's coalescent is one of the most popular models in population genetics. It describes the genealogy of a population whose genetic composition evolves in time according to the Wright-Fisher model, or suitable approximations of it…

统计方法学 · 统计学 2018-04-20 Stefano Favaro , Shui Feng , Paul A. Jenkins

The Moran discrete process and the Wright-Fisher modelare the most popular models in population genetics. It is common tounderstand the dynamics of these models to use an approximating diffusionprocess, called Wright-Fisher diffusion. Here,…

概率论 · 数学 2019-05-13 Gorgui Gackou , A Guillin , Arnaud Personne

In many applications, it is of interest to study trends over time in relationships among categorical variables, such as age group, ethnicity, religious affiliation, political party and preference for particular policies. At each time point,…

统计方法学 · 统计学 2012-05-15 Tsuyoshi Kunihama , David B. Dunson

Longitudinal molecular data of rapidly evolving viruses and pathogens provide information about disease spread and complement traditional surveillance approaches based on case count data. The coalescent is used to model the genealogy that…

应用统计 · 统计学 2020-09-07 Lorenzo Cappello , Julia A. Palacios

We propose a novel use of a recent new computational tool for Bayesian inference, namely the Approximate Bayesian Computation (ABC) methodology. ABC is a way to handle models for which the likelihood function may be intractable or even…

统计计算 · 统计学 2014-03-04 Clara Grazian , Brunero Liseo

Motivated by the need for rigorous and scalable evaluation of large language models, we study contextual preference inference for pairwise comparison functionals of context-dependent preference score functions across domains. Focusing on…

机器学习 · 统计学 2025-09-09 Yichi Zhang , Alexander Belloni , Ethan X. Fang , Junwei Lu , Xiaoan Xu

A number of methods have been developed to infer differential rates of species diversification through time and among clades using time-calibrated phylogenetic trees. However, we lack a general framework that can delineate and quantify…

定量方法 · 定量生物学 2015-06-18 Daniel L. Rabosky

This document is due to appear as a chapter of the forthcoming Handbook of Approximate Bayesian Computation (ABC) by S. Sisson, L. Fan, and M. Beaumont. Here we describe some of the circumstances under which statistical ecologists might…

统计方法学 · 统计学 2015-11-10 Matteo Fasiolo , Simon N. Wood
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