相关论文: Simulated Cytoskeletal Collapse via Tau Degradatio…
The formation, maintenance and reorganization of the cytoskeletal filament network is essential for a number of cellular processes. While the crucial role played by active forces generated by motor proteins has been studied extensively,…
The paper proposes a novel approach of survival transformers and extreme gradient boosting models in predicting cognitive deterioration in individuals with mild cognitive impairment (MCI) using metabolomics data in the ADNI cohort. By…
Amyloid-$\beta$ (A$\beta$) plaques in conjunction with hyperphosphorylated tau proteins in the form of neurofibrillary tangles are the two neuropathological hallmarks of Alzheimer's disease. It is well-known that the identification of…
In this paper, we consider the nonlinear dynamical behaviors of some tabu leaning neuron models. We first consider a tabu learning single neuron model. By choosing the memory decay rate as a bifurcation parameter, we prove that Hopf…
Alzheimer's disease (AD) is a common neurodegenerative disorder nowadays. Amyloid-beta (A$\beta$) and tau proteins are among the main contributors to the development or propagation of AD. In AD, A$\beta$ proteins clump together to form…
Three major biomarkers: beta-amyloid (A), pathologic tau (T), and neurodegeneration (N), are recognized as valid proxies for neuropathologic changes of Alzheimer's disease. While there are extensive studies on cerebrospinal fluids…
The simultaneous condensation of electronic and structural degrees of freedom gives rise to new states of matter, including superconductivity and charge-density-wave formation. When exciting such a condensed system, it is commonly assumed…
If a theory has more than one classically stable vacuum, quantum tunneling and thermal jumps make the transition between the vacua possible. The transition happens through a first order phase transition started by nucleation of a bubble of…
Microtubules are highly regulated dynamic elements of the cytoskeleton of eukaryotic cells. One of the regulation mechanisms observed in living cells is the severing by the proteins katanin and spastin. We introduce a model for the dynamics…
Spontaneous collapse models aim to resolve the measurement problem in quantum mechanics by considering wave-function collapse as a physical process. We analyze how these models affect a decaying flavor-oscillating system whose evolution is…
Recent laboratory experiments have revealed that destructive collisions of icy dust particles may occur at much lower velocities than previously believed. These low fragmentation velocities push down the maximum grain size in collisional…
A phase diagram for a one dimensional fiber bundle model is constructed with a continuous variation in two parameters guiding dynamics of the model: strength of disorder and system size. We monitor the successive events of fiber rupture in…
Fracture in aluminum alloys with precipitates involves at least two mechanisms, namely, ductile fracture of the aluminum-rich matrix and brittle fracture of the precipitates. In this work, a coupled crystal plasticity-phase field model for…
Motivated by results from an earlier Brownian Dynamics (BD) simulation for the collapse of a single, stiff polymer in a poor solvent [B. Schnurr, F. C. MacKintosh, and D. R. M. Williams, Europhys. Lett. 51 (3), 279 (2000)] we calculate the…
We investigate the fracture process of a bundle of fibers with random Young modulus and a constant breaking strength. For two component systems we show that the strength of the mixture is always lower than the strength of the individual…
Topological Anderson insulators (TAIs) provide a mechanism for topological phase transitions in disordered systems and have implications for quantum material design. In this work, we investigate the emergence of multiple TAIs in a…
We study the dynamics of pattern formation in a minimal model for active mixtures made of microtubules and molecular motors. We monitor the evolution of the (conserved) microtubule density and of the (non-conserved) nematic order parameter,…
Inelastic collapse is found in a two-dimensional system of inelastic hard disks confined between two walls which act as an energy source. As the coefficient of restitution is lowered, there is a transition between a state containing small…
The interplay of interactions and disorder is studied using the Anderson-Hubbard model within the typical medium dynamical cluster approximation. Treating the interacting, non-local cluster self-energy ($\Sigma_c[{\cal \tilde{G}}](i,j\neq…
Dilaton stabilization may occur in a theory based on a single asymptotically free gauge group with matter due to an interplay between quantum modification of the moduli space and tree-level superpotential. We present a toy model where such…