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Microscope mode imaging for secondary ion mass spectrometry is a technique with the promise of simultaneous high spatial resolution and high speed imaging of biomolecules from complex surfaces. Technological developments such as new…

仪器与探测器 · 物理学 2013-09-05 András Kiss , Donald F. Smith , Julia H. Jungmann , Ron M. A. Heeren

This paper presents a spectra normalization method for laser-induced breakdown spectroscopy (LIBS) measurements by converting the recorded characteristic line intensity at varying conditions to the intensity under a standard condition with…

等离子体物理 · 物理学 2015-05-28 Zhe Wang , Lizhi Li , Logan West , Zheng Li , Weidou Ni

The noise in the depth profiles of secondary ion mass spectrometry (SIMS) is studied using different samples under various experimental conditions. Despite the noise contributions from various parts of the dynamic SIMS process, its overall…

材料科学 · 物理学 2009-10-28 D. P. Chu , M. G. Dowsett , G. A. Cooke

Historically, many advances in superconducting radio frequency (SRF) cavities destined for use in advanced particle accelerators have come empirically, through the iterative procedure of modifying processing and then performance testing.…

加速器物理 · 物理学 2018-05-22 J. Tuggle , U. Pudasaini , A. S. Palczewski , C. E. Reece , F. A. Stevie , M. J. Kelley

Biological tissue imaging by secondary ion mass spectrometry has seen rapid development with the commercial availability of polyatomic primary ion sources. Endogenous lipids and other small bio-molecules can now be routinely mapped on the…

Mass Spectrometry (MS) is a largely used analytical technique in biology with applications such as the determination of molecule masses or the elucidation of structural data. Fourier Transform Ion Cyclotron Resonance MS is one…

化学物理 · 物理学 2019-06-17 Laura Duciel , Afef Cherni , Marc-André Delsuc

High-throughput spectrometers are capable of producing data sets containing thousands of spectra for a single biological sample. These data sets contain a substantial amount of redundancy from peptides that may get selected multiple times…

数据结构与算法 · 计算机科学 2013-01-08 Fahad Saeed , Trairak Pisitkun , Mark A. Knepper , Jason D. Hoffert

A compact resonance ionization mass spectrometer is developed using two laser diodes and a quadrupole mass spectrometer to perform trace element analysis of potassium. With the help of a narrow linewidth of the laser diode, the isotope…

原子物理 · 物理学 2010-11-29 Yoshihiro Iwata , Yoshizumi Inoue , Makoto Minowa

Mass spectrometry, especially so-called tandem mass spectrometry, is commonly used to assess the chemical diversity of samples. The resulting mass fragmentation spectra are representations of molecules of which the structure may have not…

机器学习 · 计算机科学 2025-02-18 Niek de Jonge , Justin J. J. van der Hooft , Daniel Probst

A simple resonance ionization mass spectrometer is built with a Quadrupole Mass Spectrometer (QMS) and two laser diodes aiming at trace analysis of potassium. The overall detection efficiency is estimated comparing the yields of resonance…

原子物理 · 物理学 2015-05-13 Yoshihiro Iwata , Yoshizumi Inoue , Makoto Minowa

Methods to visualize the two-dimensional distribution of molecules by mass spectrometric imaging evolve rapidly and yield novel applications in biology, medicine, and material surface sciences. Most mass spectrometric imagers acquire high…

仪器与探测器 · 物理学 2011-03-11 Casimir Bamberger , Uwe Renz , Andreas Bamberger

The detailed shapes of spectral line profiles provide valuable information about the emitting plasma, especially when the plasma contains an unresolved mixture of velocities, temperatures, and densities. As a result of finite spectral…

太阳与恒星天体物理 · 物理学 2015-07-17 James A. Klimchuk , Spiros Patsourakos , Durgesh Tripathi

Recently, sparsity-based algorithms are proposed for super-resolution spectrum estimation. However, to achieve adequately high resolution in real-world signal analysis, the dictionary atoms have to be close to each other in frequency,…

机器学习 · 统计学 2015-06-05 Yiyuan She , Huanghuang Li , Jiangping Wang , Dapeng Wu

The knowledge of absolute fluxes of reactive species such as radicals or energetic ions to the surface is crucial for understanding the growth or etching of thin films. These species have due to their high reactivity very low densities and…

等离子体物理 · 物理学 2011-05-16 Jan Benedikt , Dirk Ellerweg , Achim von Keudell

Coupling a multi-capillary column (MCC) with an ion mobility (IM) spectrometer (IMS) opened a multitude of new application areas for gas analysis, especially in a medical context, as volatile organic compounds (VOCs) in exhaled breath can…

其他计算机科学 · 计算机科学 2014-05-22 Dominik Kopczynski , Sven Rahmann

Isochronous Mass Spectrometry (IMS) in heavy-ion storage rings is an excellent experimental method for precision mass measurements of exotic nuclei. In the IMS, the storage ring is tuned in a special isochronous ion-optical mode. Thus, the…

The concept of isochronous mass spectrometry (IMS) applying two time-of-flight (TOF) detectors originated many years ago at GSI. However, the corresponding method for data analysis has never been discussed in detail. Recently, two TOF…

Mass spectrometry-based metabolomic analysis depends upon the identification of spectral peaks by their mass and retention time. Statistical analysis that follows the identification currently relies on one main peak of each compound.…

定量方法 · 定量生物学 2014-03-20 Tommi Suvitaival , Simon Rogers , Samuel Kaski

Dual-comb spectroscopy (DCS) is a powerful Fourier-transform spectroscopic technique that provides high-speed, high-resolution, and broadband measurements without moving parts. However, the high peak power of mode-locked pulses limits the…

光学 · 物理学 2025-09-30 Wei Long , Xinru Cao , Xiangze Ma , Jiaqi Zhou , Wenbin He , Dijun Chen

A multichannel dual-comb spectroscopy (DCS) approach for high-resolution, broadband spectral measurements is presented, demonstrating its effectiveness in studying complex atomic systems. By implementing a photodetector array, we enhance…

原子物理 · 物理学 2025-03-14 R. Aramyan , O. Tretiak , S. S. Sahoo , D. Budker
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