相关论文: Weak self-interactions of globular proteins studie…
Nuclear structure properties and weak interaction rates of neutron rich even even iron (Fe) isotopes (A = 50 70) are investigated using the Interacting Boson Model1 (IBM1) and the proton neutron Quasiparticle Random Phase Approximation…
A theoretical study on the weak scattering formulation for flexural waves in thin elastic plates loaded by point-like resonators is reported. Our approach employs the Born approximation and far-field asymptotics of the Green function to…
We present nuclear structure factors that describe the generalized spin-independent coupling of weakly interacting massive particles (WIMPs) to nuclei. Our results are based on state-of-the-art nuclear structure calculations using the…
Motivation: Human cancer is caused by the accumulation of somatic mutations in tumor suppressors and oncogenes within the genome. In the case of oncogenes, recent theory suggests that there are only a few key "driver" mutations responsible…
The present work provides a profound analytical and numerical analysis of the material properties of SFRC on the mesoscale as well as the resulting correlation structure taking into account the probabilistic characteristics of the fiber…
The native state structures of globular proteins are stable and well-packed indicating that self-interactions are favored over protein-solvent interactions under folding conditions. We use this as a guiding principle to derive the geometry…
We theoretically investigate the static structure factor of an interacting Fermi gas near the BEC-BCS crossover at large momenta. Due to short-range two-body interactions, we predict that the structure factor of unlike spin correlations…
Rigidity analysis using the "pebble game" can usefully be applied to protein crystal structures to obtain information on protein folding, assembly and the structure-function relationship. However, previous work using this technique has not…
Geometric frustration offers a pathway to soft matter self-assembly with controllable finite sizes. While the understanding of frustration in soft matter assembly derives almost exclusively from continuum elastic descriptions, a current…
A method based on the Gibbs' adsorption isotherm is developed to calculate the decrease in interfacial free energy resulting from solute segregation at an internal interface, built on measured concentration profiles. Utilizing atom-probe…
We present a feature functional theory - binding predictor (FFT-BP) for the protein-ligand binding affinity prediction. The underpinning assumptions of FFT-BP are as follows: i) representability: there exists a microscopic feature vector…
It is shown that by assuming Gribov factorization to hold at low $x$ one obtains a simple relation between the structure function of the proton and that of the photon. By interpreting an observed structure in deep inelastic scattering (DIS)…
The effective Coulomb interaction between globular proteins is calculated as a function of monovalent salt concentration $c_s$, by explicit Molecular Dynamics simulations of pairs of model proteins in the presence of microscopic co and…
We present a comprehensive study of weak transition form factors and decay observables of the $B_s$ meson in transitions to pseudoscalar ($P$) and vector ($V$) mesons. The $B_s \to P(V)$ form factors are calculated using the self-consistent…
We use computer simulations to investigate self-assembly in a system of model chaperonin proteins, and in an Ising lattice gas. We discuss the mechanisms responsible for rapid and efficient assembly in these systems, and we use measurements…
Integral membrane proteins deform the surrounding bilayer creating long-ranged forces that influence distant proteins. These forces can be attractive or repulsive, depending on the proteins' shape, height, contact angle with the bilayer, as…
Measuring the structure factor, S(q), of a dispersion of particles by Small-Angle X-ray Scattering provides a unique method to investigate the spatial arrangement of colloidal particles. However, it is impossible to find the exact location…
Protein-protein interactions (PPIs) are crucial in regulating numerous cellular functions, including signal transduction, transportation, and immune defense. As the accuracy of multi-chain protein complex structure prediction improves, the…
In a recent article, we described how the microscopic structure of density-density correlations in the fluid interfacial region, for systems with short-ranged forces, can be understood by considering the resonances of the local structure…
A microscopic theory of the free energy barriers and folding routes for minimally frustrated proteins is presented, greatly expanding on the presentation of the variational approach outlined previously [J. J. Portman, S. Takada, P. G.…