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This paper proposes an efficient system for classifying cervical cancer cells using pre-trained convolutional neural networks (CNNs). We first fine-tune five pre-trained CNNs and minimize the overall cost of misclassification by…

计算机视觉与模式识别 · 计算机科学 2024-02-27 Ashfiqun Mustari , Rushmia Ahmed , Afsara Tasnim , Jakia Sultana Juthi , G M Shahariar

Background Precise prediction of cancer types is vital for cancer diagnosis and therapy. Important cancer marker genes can be inferred through predictive model. Several studies have attempted to build machine learning models for this task…

基因组学 · 定量生物学 2019-06-20 Milad Mostavi , Yu-Chiao Chiu , Yufei Huang , Yidong Chen

Complex data features, such as unmodelled censored event times and variables with time-dependent effects, are common in cancer recurrence studies and pose challenges for Bayesian survival modelling. Current methodologies for predictive…

统计方法学 · 统计学 2026-01-12 Saku Suorsa , Aki Vehtari

This paper presents a novel online identification algorithm for nonlinear regression models. The online identification problem is challenging due to the presence of nonlinear structure in the models. Previous works usually ignore the…

最优化与控制 · 数学 2022-07-21 Guang-Yong Chen , Min Gan , Jing Chen , Long Chen

Understanding how molecular alterations propagate across biological systems to drive disease remains a central challenge. Although high-throughput profiling enables comprehensive characterization of tumor states, most models neglect…

定量方法 · 定量生物学 2026-05-11 Kyle Higgins , Guadalupe Gonzalez , Dennis Veselkov , Ivan Laponogov , Kirill Veselkov

An accurate prediction of protein-nucleic acid binding affinity is vital for deciphering genomic processes, yet existing approaches often struggle in reconciling high accuracy with interpretability and computational efficiency. In this…

定量方法 · 定量生物学 2025-10-28 Mushal Zia , Faisal Suwayyid , Yuta Hozumi , JunJie Wee , Hongsong Feng , Guo-Wei Wei

In recent years the importance of finding a meaningful pattern from huge datasets has become more challenging. Data miners try to adopt innovative methods to face this problem by applying feature selection methods. In this paper we propose…

机器学习 · 计算机科学 2014-03-11 Mehdi Naseriparsa , Amir-masoud Bidgoli , Touraj Varaee

Artificial intelligence (AI) is transforming cancer diagnosis and treatment. The intricate nature of this disease necessitates the collaboration of diverse stakeholders with varied expertise to ensure the effectiveness of cancer research.…

数字图书馆 · 计算机科学 2025-12-30 Shahab Mosallaie , Andrea Schiffauerova , Ashkan Ebadi

Driven by significant improvements in architectural design and training pipelines, computer vision has recently experienced dramatic progress in terms of accuracy on classic benchmarks such as ImageNet. These highly-accurate models are…

计算机视觉与模式识别 · 计算机科学 2023-06-01 Denis Kuznedelev , Eldar Kurtic , Elias Frantar , Dan Alistarh

With the advancement of high-throughput biotechnologies, we increasingly accumulate biomedical data about diseases, especially cancer. There is a need for computational models and methods to sift through, integrate, and extract new…

定量方法 · 定量生物学 2020-07-03 Thomas Gaudelet , Noel Malod-Dognin , Natasa Przulj

The identification of cancer genes is a critical yet challenging problem in cancer genomics research. Existing computational methods, including deep graph neural networks, fail to exploit the multilayered gene-gene interactions or provide…

机器学习 · 计算机科学 2023-05-04 Michail Chatzianastasis , Michalis Vazirgiannis , Zijun Zhang

The prediction plays the important role in detecting efficient protection and therapy of cancer. The prediction of mutations in gene needs a diagnostic and classification, which is based on the whole database (big dataset), to reach…

机器学习 · 计算机科学 2016-08-10 Ayad Ghany Ismaeel , Dina Yousif Mikhail

Classification is the task of assigning a new instance to one of a set of predefined categories based on the attributes of the instance. A classification tree is one of the most commonly used techniques in the area of classification. In…

统计方法学 · 统计学 2021-08-26 Abdulmajeed Atiah Alharbi , Frank P. A. Coolen , Tahani Coolen-Maturi

The past years have seen a considerable increase in cancer cases. However, a cancer diagnosis is often complex and depends on the types of images provided for analysis. It requires highly skilled practitioners but is often time-consuming…

图像与视频处理 · 电气工程与系统科学 2022-10-24 Solene Bechelli

Gene selection plays a pivotal role in oncology research for improving outcome prediction accuracy and facilitating cost-effective genomic profiling for cancer patients. This paper introduces two gene selection strategies for deep…

基因组学 · 定量生物学 2024-03-05 Akhila Krishna , Ravi Kant Gupta , Pranav Jeevan , Amit Sethi

Identifying the mutations that drive cancer growth is key in clinical decision making and precision oncology. As driver mutations confer selective advantage and thus have an increased likelihood of occurrence, frequency-based statistical…

基因组学 · 定量生物学 2021-05-04 Adnan Akbar , Andrey Solovyev , John W Cassidy , Nirmesh Patel , Harry W Clifford

The Deep Convolutional Neural Network (DCNN) is one of the most powerful and successful deep learning approaches. DCNNs have already provided superior performance in different modalities of medical imaging including breast cancer…

计算机视觉与模式识别 · 计算机科学 2018-11-13 Md Zahangir Alom , Chris Yakopcic , Tarek M. Taha , Vijayan K. Asari

Despite significant medical advancements, cancer remains the second leading cause of death, with over 600,000 deaths per year in the US. One emerging field, pathway analysis, is promising but still relies on manually derived wet lab data,…

机器学习 · 计算机科学 2025-09-17 Rishab Parthasarathy , Achintya Bhowmik

Learning in neural networks is often framed as a problem in which targeted error signals are directly propagated to parameters and used to produce updates that induce more optimal network behaviour. Backpropagation of error (BP) is an…

神经与进化计算 · 计算机科学 2023-01-30 Nasir Ahmad , Ellen Schrader , Marcel van Gerven

Causal structure discovery from observational data is fundamental to the causal understanding of autonomous systems such as medical decision support systems, advertising campaigns and self-driving cars. This is essential to solve well-known…