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We consider a joint survival and mixed-effects model to explain the survival time from longitudinal data and high-dimensional covariates in a population. The longitudinal data is modeled using a non linear mixed-effects model to account for…

统计理论 · 数学 2025-08-06 Antoine Caillebotte , Estelle Kuhn , Sarah Lemler

We address the problem of survival regression modelling with multivariate responses and nonlinear covariate effects. Our model extends the proportional hazards model by introducing several weakly-parametric elements: the marginal baseline…

统计方法学 · 统计学 2025-10-16 Na Lei , Mark A. Wolters , Wenqing He

Graphical models are commonly used tools for modeling multivariate random variables. While there exist many convenient multivariate distributions such as Gaussian distribution for continuous data, mixed data with the presence of discrete…

机器学习 · 统计学 2014-04-30 Jianqing Fan , Han Liu , Yang Ning , Hui Zou

Few Bayesian methods for analyzing high-dimensional sparse survival data provide scalable variable selection, effect estimation and uncertainty quantification. Such methods often either sacrifice uncertainty quantification by computing…

统计方法学 · 统计学 2022-07-06 Michael Komodromos , Eric Aboagye , Marina Evangelou , Sarah Filippi , Kolyan Ray

Although the Cox proportional hazards model is well established and extensively used in the analysis of survival data, the proportional hazards (PH) assumption may not always hold in practical scenarios. The class of semiparametric…

统计方法学 · 统计学 2025-10-21 Junkai Yin , Yue Zhang , Zhangsheng Yu

The use of massive survival data has become common in survival analysis. In this study, a subsampling algorithm is proposed for the Cox proportional hazards model with time-dependent covariates when the sample is extraordinarily large but…

统计计算 · 统计学 2023-02-07 Nan Qiao , Wangcheng Li , Feng Xiao , Cunjie Lin , Yong Zhou

Estimating covariances between financial assets plays an important role in risk management. In practice, when the sample size is small compared to the number of variables, the empirical estimate is known to be very unstable. Here, we…

计算工程、金融与科学 · 计算机科学 2019-04-19 Rajbir-Singh Nirwan , Nils Bertschinger

In practice, there often exist unobserved variables, also termed hidden variables, associated with both the response and covariates. Existing works in the literature mostly focus on linear regression with hidden variables. However, when the…

统计方法学 · 统计学 2025-09-03 Inbeom Lee , Yang Ning

We develop a framework for derivative Gaussian process latent variable models (DGP-LVMs) that can handle multi-dimensional output data using modified derivative covariance functions. The modifications account for complexities in the…

统计方法学 · 统计学 2025-06-10 Soham Mukherjee , Manfred Claassen , Paul-Christian Bürkner

In this paper, we study the problem of learning multi-dimensional Gaussian Mixture Models (GMMs), with a specific focus on model order selection and efficient mixing distribution estimation. We first establish an information-theoretic lower…

机器学习 · 统计学 2026-03-23 Xinyu Liu , Hai Zhang

A prevalent feature of high-dimensional data is the dependence among covariates, and model selection is known to be challenging when covariates are highly correlated. To perform model selection for the high-dimensional Cox proportional…

统计方法学 · 统计学 2022-10-04 Pierre Bayle , Jianqing Fan

With the availability of high dimensional genetic biomarkers, it is of interest to identify heterogeneous effects of these predictors on patients' survival, along with proper statistical inference. Censored quantile regression has emerged…

统计方法学 · 统计学 2021-07-26 Zhe Fei , Qi Zheng , Hyokyoung G. Hong , Yi Li

Low-dimensional embeddings for data from disparate sources play critical roles in multi-modal machine learning, multimedia information retrieval, and bioinformatics. In this paper, we propose a supervised dimensionality reduction method…

机器学习 · 计算机科学 2021-01-15 Yanjun Li , Bihan Wen , Hao Cheng , Yoram Bresler

Modern network data analysis often involves analyzing network structures alongside covariate features to gain deeper insights into underlying patterns. However, traditional covariate-assisted statistical network models may not adequately…

统计方法学 · 统计学 2025-05-07 Peng Zhao , Yabo Niu

High-dimensional multivariate spatial-temporal data arise frequently in a wide range of applications; however, there are relatively few statistical methods that can simultaneously deal with spatial, temporal and variable-wise dependencies…

统计方法学 · 统计学 2020-02-05 Elynn Y. Chen , Xin Yun , Rong Chen , Qiwei Yao

High-dimensional data often arise from clinical genomics research to infer relevant predictors of a particular trait. A way to improve the predictive performance is to include information on the predictors derived from prior knowledge or…

统计方法学 · 统计学 2023-03-13 Claudio Busatto , Mark van de Wiel

Latent variable models (LVMs) learn probabilistic models of data manifolds lying in an \emph{ambient} Euclidean space. In a number of applications, a priori known spatial constraints can shrink the ambient space into a considerably smaller…

机器学习 · 统计学 2019-02-26 Anton Mallasto , Søren Hauberg , Aasa Feragen

A powerful tool for the analysis of nonrandomized observational studies has been the potential outcomes model. Utilization of this framework allows analysts to estimate average treatment effects. This article considers the situation in…

统计理论 · 数学 2019-05-31 Debashis Ghosh , Efrén Cruz-Cortés

Variable selection problem for the nonlinear Cox regression model is considered. In survival analysis, one main objective is to identify the covariates that are associated with the risk of experiencing the event of interest. The Cox…

机器学习 · 统计学 2022-11-18 Kexuan Li

A novel mixture cure frailty model is introduced for handling censored survival data. Mixture cure models are preferable when the existence of a cured fraction among patients can be assumed. However, such models are heavily underexplored:…

统计方法学 · 统计学 2025-05-07 Fatih Kızılaslan , David Michael Swanson , Valeria Vitelli