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Microarray data come from many steps of production and have been known to contain noise. The pre-processing is implemented to reduce the noise, where the background is corrected. Prior to further analysis, many Illumina BeadArrays users had…

统计方法学 · 统计学 2015-02-18 Rohmatul Fajriyah

Motivation: Illumina BeadArray technology includes negative control features that allow a precise estimation of the background noise. As an alternative to the background subtraction proposed in BeadStudio which leads to an important loss of…

应用统计 · 统计学 2012-09-19 Sandra Plancade , Yves Rozenholc , Eiliv Lund

We use convolutional neural networks (CNNs) and recurrent neural networks (RNNs) to estimate the parameters of strong gravitational lenses from interferometric observations. We explore multiple strategies and find that the best results are…

We present Bayesian inference results from an extensive injection-recovery campaign to test the validity of three state of the art quasicircular gravitational waveform models: \textsc{SEOBNRv5PHM}, \textsc{IMRPhenomTPHM},…

广义相对论与量子宇宙学 · 物理学 2025-10-21 Sarp Akçay , Charlie Hoy , Jake Mac Uilliam

Machine learning models of accelerator systems (`surrogate models') are able to provide fast, accurate predictions of accelerator physics phenomena. However, approaches to date typically do not include measured input diagnostics, such as…

加速器物理 · 物理学 2021-04-06 Lipi Gupta , Auralee Edelen , Nicole Neveu , Aashwin Mishra , Christopher Mayes , Young-Kee Kim

Low-Rank Adaptation (LoRA) has gained popularity for fine-tuning large foundation models, leveraging low-rank matrices $\mathbf{A}$ and $\mathbf{B}$ to represent weight changes (i.e., $\Delta \mathbf{W} = \mathbf{B} \mathbf{A}$). This…

机器学习 · 计算机科学 2025-07-02 Aochuan Chen , Jiashun Cheng , Zijing Liu , Ziqi Gao , Fugee Tsung , Yu Li , Jia Li

Measurement error in count data is common but underexplored in the literature, particularly in contexts where observed scores are bounded and arise from discrete scoring processes. Motivated by applications in oral reading fluency…

统计方法学 · 统计学 2025-06-26 Yuqiu Yang , Christina Vu , Cornelis J. Potgieter , Xinlei Wang , Akihito Kamata

Implicit Neural Representations (INRs), as a versatile representation paradigm, have achieved success in various computer vision tasks. Due to the spectral bias of the vanilla multi-layer perceptrons (MLPs), existing methods focus on…

计算机视觉与模式识别 · 计算机科学 2025-05-27 Kexuan Shi , Hai Chen , Leheng Zhang , Shuhang Gu

Gamma-ray bursts (GRBs) are challenging to identify due to their transient nature, complex temporal profiles, and limited observational datasets. We address this with a one-dimensional convolutional neural network integrated with an…

In the last decade, fNIRS has provided a non-invasive method to investigate neural activation in developmental populations. Despite its increasing use in developmental cognitive neuroscience, there is little consistency or consensus on how…

神经元与认知 · 定量生物学 2022-11-29 Maria Laura Filippetti , Javier Andreu-Perez , Carina de Klerk , Chloe Richmond , Silvia Rigato

Medical foundation models have achieved remarkable clinical performance, yet their robustness under real-world perturbations remains underexplored. We present a robustness benchmark comprising 40 perturbation types (12 base, 28…

计算机视觉与模式识别 · 计算机科学 2026-05-26 Xiangxiang Cui , Tianjin Huang , Yifang Wang , Lijie Hu , Lu Yin

Combining the strengths of model-based iterative algorithms and data-driven deep learning solutions, deep unrolling networks (DuNets) have become a popular tool to solve inverse imaging problems. While DuNets have been successfully applied…

机器学习 · 计算机科学 2024-04-02 Qingping Zhou , Jiayu Qian , Junqi Tang , Jinglai Li

The retrieval-augmented generation (RAG) approach is used to reduce the confabulation of large language models (LLMs) for question answering by retrieving and providing additional context coming from external knowledge sources (e.g., by…

计算与语言 · 计算机科学 2024-10-30 Alexander Bondarenko , Adrian Viehweger

We present the intensity foreground algorithms and model employed within the BeyondPlanck analysis framework. The BeyondPlanck analysis is aimed at integrating component separation and instrumental parameter sampling within a global…

Foundation Models have demonstrated significant success across various domains in Artificial Intelligence (AI), yet their capabilities for brainwave modeling remain unclear. In this paper, we comprehensively evaluate current Large Brainwave…

This study examines whether Low-Rank Adaptation (LoRA) fine-tuned Large Language Models (LLMs) can approximate the performance of fully fine-tuned models in generating human-interpretable decisions and explanations for malware…

密码学与安全 · 计算机科学 2025-11-26 Stephen C. Gravereaux , Sheikh Rabiul Islam

Due to the demand for efficient fine-tuning of large language models, Low-Rank Adaptation (LoRA) has been widely adopted as one of the most effective parameter-efficient fine-tuning methods. Nevertheless, while LoRA improves efficiency,…

计算与语言 · 计算机科学 2025-06-13 Naibin Gu , Zhenyu Zhang , Xiyu Liu , Peng Fu , Zheng Lin , Shuohuan Wang , Yu Sun , Hua Wu , Weiping Wang , Haifeng Wang

Robust machine learning for regulatory genomics is studied under biologically and technically induced distribution shifts. Deep convolutional and attention based models achieve strong in distribution performance on DNA regulatory sequence…

基因组学 · 定量生物学 2026-02-20 Yiyao Yang

Despite the success and popularity of oligonucleotide arrays as a high-throughput technique for measuring mRNA expression levels, quantitative calibration studies have until now been limited. The main reason is that suitable data was not…

生物物理 · 物理学 2007-05-23 Felix Naef , Nicholas D. Socci , Marcelo Magnasco

Pre-trained Transformers often exhibit over-confidence in source patterns and difficulty in forming new target-domain patterns during fine-tuning. We formalize the mechanism of output saturation leading to gradient suppression through…

机器学习 · 计算机科学 2025-11-04 Wang Zixian
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