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Routinely navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell's crucial components, such as neurotransmitters and organelles. They generate force and pull cargo,…

生物物理 · 物理学 2012-09-28 Bartosz Lisowski , Michał Żabicki

The twisting and writhing of a cell body and associated mechanical stresses is an underappreciated constraint on microbial self-propulsion. Multi-flagellated bacteria can even buckle and writhe under their own activity as they swim through…

软凝聚态物质 · 物理学 2023-09-25 Wilson Lough , Douglas B. Weibel , Saverio E. Spagnolie

We analyze the collective behavior of hydrodynamically coupled molecular motors. We show that the local fluxes induced by motors displacement can induce the experimentally observed bidirectional motion of cargoes and vesicles. By means of a…

软凝聚态物质 · 物理学 2017-11-22 P. Malgaretti , I. Pagonabarraga , J. F. Joanny

E.coli serves as prototype for the study of peritrichous enteric bacteria that perform runs and tumbles alternately. Bacteria run forward as a result of the counterclockwise (CCW) rotation of their flagella bundle and perform tumbles when…

生物物理 · 物理学 2019-11-05 G. Fier , D. Hansmann , R. C. Buceta

A light-driven molecular motor system is investigated using a multi-state Brownian ratchet model described by a single effective coordinate with multiple electronic states in a dissipative environment. The rotational motion of the motor…

化学物理 · 物理学 2019-03-22 Tatsushi Ikeda , Arend G. Dijkstra , Yoshitaka Tanimura

Escherichia coli swims using flagella activated by rotary motors. The direction of rotation of the motors is indirectly regulated by the binding of a single messenger protein. The conformational spread model has been shown to accurately…

定量方法 · 定量生物学 2017-03-08 Alberto Pezzotta , Matteo Adorisio , Antonio Celani

The presence of a nearby boundary is likely to be important in the life cycle and evolution of motile flagellate bacteria. This has led many authors to employ numerical simulations to model near-surface bacterial motion and compute…

生物物理 · 物理学 2021-09-21 Orrin Shindell , Hoa Nguyen , Nicholas Coltharp , Frank Healy , Bruce Rodenborn

The type IV pilus retraction motor is found in many important bacterial pathogens. It is the strongest known linear motor protein and is required for bacterial infectivity. We characterize the dynamics of type IV pilus retraction in terms…

生物物理 · 物理学 2007-05-23 Martin Linden , Emil Johansson , Ann-Beth Jonsson , Mats Wallin

It is widely believed that the swimming speed, $v$, of many flagellated bacteria is a non-monotonic function of the concentration, $c$, of high-molecular-weight linear polymers in aqueous solution, showing peaked $v(c)$ curves. Pores in the…

Artificial bacteria flagella (ABFs) are magnetic helical micro-swimmers that can be remotely controlled via a uniform, rotating magnetic field. Previous studies have used the heterogeneous response of microswimmers to external magnetic…

流体动力学 · 物理学 2022-01-05 Lucas Amoudruz , Petros Koumoutsakos

Flagellated bacteria on nutrient-rich substrates can differentiate into a swarming state and move in dense swarms across surfaces. A recent experiment measured the flow in the fluid around an Escherichia coli swarm (Wu, Hosu and Berg, 2011…

生物物理 · 物理学 2016-07-28 Justas Dauparas , Eric Lauga

The Cellular Potts Model (CPM) succesfully simulates drainage and shear in foams. Here we use the CPM to investigate instabilities due to the flow of a single large bubble in a dry, monodisperse two-dimensional flowing foam. As in…

软凝聚态物质 · 物理学 2009-11-11 Soma Sanyal , James A. Glazier

Fast and efficient state preparation of molecules can be accomplished by optical pumping. Molecular structure that most obviously facilitates cycling involves a strong electronic transition, with favorable vibrational branching (diagonal…

原子物理 · 物理学 2023-03-29 James B. Dragan , Ivan O. Antonov , Brian C. Odom

Many swimming microorganisms, such as bacteria and sperm, use flexible flagella to move through viscoelastic media in their natural environments. In this paper we address the effects a viscoelastic fluid has on the motion and beating…

软凝聚态物质 · 物理学 2009-11-13 Henry C. Fu , Charles W. Wolgemuth , Thomas R. Powers

Movements of molecular motors on cytoskeletal filaments are described by directed walks on a line. Detachment from this line is allowed to occur with a small probability. Motion in the surrounding fluid is described by symmetric random…

统计力学 · 物理学 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

Molecular motors transport various cargos along cytoskeletal filaments, analogous to trucks on roads. In contrast to vehicles, however, molecular motors do not work alone but in small teams. We describe a simple model for the transport of a…

统计力学 · 物理学 2008-07-08 Melanie J. I. Müller , Janina Beeg , Rumiana Dimova , Stefan Klumpp , Reinhard Lipowsky

The mathematical formulation of the model for molecular movement of single motor proteins driven by cyclic biochemical reactions in an aqueous environment leads to a drifted Brownian motion characterized by coupled diffusion equations. In…

统计力学 · 物理学 2007-05-23 Hong Qian

Many cell functions are accomplished thanks to intracellular transport mechanisms of macromolecules along filaments. Molecular motors such as dynein or kinesin are proteins playing a primary role in these processes. The behavior of such…

混沌动力学 · 物理学 2010-12-21 Donatello Materassi , Subhrajit Roychowdhury , Murti V. Salapaka

Many swimming bacteria naturally inhabit confined environments, yet how confinement influences their swimming behaviors remains unclear. Here, we combine experiments, continuum modeling and particle-based simulations to investigate…

生物物理 · 物理学 2025-10-13 Da Wei , Shiyuan Hu , Tangmiao Tang , Yaochen Yang , Fanlong Meng , Yi Peng

The diffusion of a molecular motor in the presence of a constant external force is considered on the basis of a simple theoretical model. The motor is represented by a Brownian particle moving in a series of parabolic potentials placed…

统计力学 · 物理学 2016-06-01 Ryota Shinagawa , Kazuo Sasaki
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