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While the standard network description of complex systems is based on quantifying links between pairs of system units, higher-order interactions (HOIs) involving three or more units play a major role in governing the collective network…

Successful biomedical relation extraction can provide evidence to researchers and clinicians about possible unknown associations between biomedical entities, advancing the current knowledge we have about those entities and their inherent…

信息检索 · 计算机科学 2020-04-22 Diana Sousa , Francisco M. Couto

Automatic phenotype concept recognition from unstructured text remains a challenging task in biomedical text mining research. Previous works that address the task typically use dictionary-based matching methods, which can achieve high…

The human brain is a complex system defined by multi-way, higher-order interactions invisible to traditional pairwise network models. Although a diverse array of analytical methods has been developed to address this shortcoming, the field…

定量方法 · 定量生物学 2025-11-11 Mohamma Reza Salehi , Ali BashirGonbadi , Hamid Soltanian-Zadeh

Existing learning analytics approaches, which often model learning processes as sequences of learner actions or homogeneous relationships, are limited in capturing the distributed, multi-faceted nature of interactions in contemporary…

社会与信息网络 · 计算机科学 2026-04-23 Shihui Feng , Baiyue He , Dragan Gasevic , Alec Kirkley

Motivation: Cell-biological processes are regulated through a complex network of interactions between genes and their products. The processes, their activating conditions, and the associated transcriptional responses are often unknown.…

分子网络 · 定量生物学 2012-02-03 Leo Lahti , Juha E. A. Knuuttila , Samuel Kaski

Ontologies provide a systematic framework for organizing and leveraging knowledge, enabling smarter and more effective decision-making. In order to advance in the capitalization and augmentation of intelligence related to nowadays…

Emotions are a subject of intense debate in various disciplines. Despite the proliferation of theories and definitions, there is still no consensus on what emotions are, and how to model the different concepts involved when we talk about -…

人工智能 · 计算机科学 2024-01-22 Stefano De Giorgis , Aldo Gangemi

Ontohub is a repository engine for managing distributed heterogeneous ontologies. The distributed nature enables communities to share and exchange their contributions easily. The heterogeneous nature makes it possible to integrate…

人工智能 · 计算机科学 2016-12-16 Mihai Codescu , Eugen Kuksa , Oliver Kutz , Till Mossakowski , Fabian Neuhaus

Neural Additive Models (NAMs) have recently demonstrated promising predictive performance while maintaining interpretability. However, their capacity is limited to capturing only first-order feature interactions, which restricts their…

机器学习 · 计算机科学 2025-11-17 Minkyu Kim , Hyun-Soo Choi , Jinho Kim

This paper continues the discussion of the representation of ontologies in the first-order logical environment FOLE. According to Gruber, an ontology defines the primitives with which to model the knowledge resources for a community of…

计算机科学中的逻辑 · 计算机科学 2023-04-25 Robert E. Kent

The NFDI4DataScience (NFDI4DS) project aims to enhance the accessibility and interoperability of research data within Data Science (DS) and Artificial Intelligence (AI) by connecting digital artifacts and ensuring they adhere to FAIR…

人工智能 · 计算机科学 2024-08-19 Genet Asefa Gesese , Jörg Waitelonis , Zongxiong Chen , Sonja Schimmler , Harald Sack

We present Ringo, a system for analysis of large graphs. Graphs provide a way to represent and analyze systems of interacting objects (people, proteins, webpages) with edges between the objects denoting interactions (friendships, physical…

Describing the processes involved in analyzing data from electrophysiology experiments to investigate the function of neural systems is inherently challenging. On the one hand, data can be analyzed by distinct methods that serve a similar…

定量方法 · 定量生物学 2024-12-09 Cristiano André Köhler , Sonja Grün , Michael Denker

Artificial intelligence (AI) has become indispensable for managing and processing the vast amounts of data generated during the COVID-19 pandemic. Ontology, which formalizes knowledge within a domain using standardized vocabularies and…

人机交互 · 计算机科学 2024-11-06 Biswanath Dutta , Debanjali Bain

The Core Data Ontology (CDO) and the Informatics Domain Model represent a transformative approach to computational systems, shifting from traditional node-centric designs to a data-centric paradigm. This paper introduces a framework where…

分布式、并行与集群计算 · 计算机科学 2024-11-14 Paul Knowles , Bart Gajderowicz , Keith Dugas

Accurate prediction of protein function is essential for elucidating molecular mechanisms and advancing biological and therapeutic discovery. Yet experimental annotation lags far behind the rapid growth of protein sequence data.…

生物大分子 · 定量生物学 2026-03-27 Mehmet Efe Akça , Gökçe Uludoğan , Arzucan Özgür , İnci M. Baytaş

The Brain-Heart Interconnectome (BHI) combines neurology and cardiology but is hindered by inefficiencies in evidence synthesis, poor adherence to quality standards, and research waste. To address these challenges, we developed an AI-driven…

Numerous cellular functions rely on protein$\unicode{x2013}$protein interactions. Efforts to comprehensively characterize them remain challenged however by the diversity of molecular recognition mechanisms employed within the proteome. Deep…

生物大分子 · 定量生物学 2023-12-08 Julia R. Rogers , Gergő Nikolényi , Mohammed AlQuraishi

Machine Learning (ML) systems are capable of reproducing and often amplifying undesired biases. This puts emphasis on the importance of operating under practices that enable the study and understanding of the intrinsic characteristics of ML…

人工智能 · 计算机科学 2025-12-01 Mayra Russo , Maria-Esther Vidal