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We discuss the hydrodynamic collective effects due to active protein molecules that are immersed in lipid bilayer membranes and modeled as stochastic force dipoles. We specifically take into account the presence of the bulk solvent which…

软凝聚态物质 · 物理学 2017-05-24 Yuto Hosaka , Kento Yasuda , Ryuichi Okamoto , Shigeyuki Komura

Besides direct molecular interactions, proteins and nanoparticles embedded in or adsorbed to membranes experience indirect interactions that are mediated by the membranes. These membrane-mediated interactions arise from the membrane…

软凝聚态物质 · 物理学 2024-07-08 Francesco Bonazzi , Thomas R. Weikl

We investigate the hydrodynamic effects on the dynamics of critical concentration fluctuations in multicomponent fluid membranes. Two geometrical cases are considered; (i) confined membrane case and (ii) supported membrane case. We…

软凝聚态物质 · 物理学 2010-11-29 Sanoop Ramachandran , Shigeyuki Komura , Kazuhiko Seki , Masayuki Imai

Particles diffusing near interfaces face anisotropic resistance to motion due to hydrodynamic interactions. While this has been extensively studied near \textit{hard} interfaces since the works of Lorentz and Brenner, our understanding of…

软凝聚态物质 · 物理学 2026-03-03 Ali Mohammadi , Zhen Li , Sophie Marbach , Micheline Abbas

In this paper we introduce a novel method to simulate lateral diffusion of inclusions in a fluctuating membrane. The regarded systems are governed by two dynamic processes: the height fluctuations of the membrane and the diffusion of the…

软凝聚态物质 · 物理学 2007-05-23 Ellen Reister-Gottfried , Stefan M. Leitenberger , Udo Seifert

We study closed liquid membranes that segregate into three phases due to differences in the chemical and physical properties of its components. The shape and in-plane membrane arrangement of the phases are coupled through phase-specific…

软凝聚态物质 · 物理学 2012-08-17 Matthew F. Demers , Rastko Sknepnek , Monica Olvera de la Cruz

We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models…

元胞自动机与格子气 · 物理学 2025-01-09 Pascal R. Buenzli , Shahak Kuba , Ryan J. Murphy , Matthew J. Simpson

We introduce a simulation strategy to consistently couple continuum biomembrane dynamics to the motion of discrete biological macromolecules residing within or on the membrane. The methodology is used to study the diffusion of integral…

软凝聚态物质 · 物理学 2009-05-26 Ali Naji , Paul J. Atzberger , Frank L. H. Brown

We use molecular dynamics simulations to study the behavior of a compressible Lennard-Jones fluid in simple shear flow in a two-dimensional nanochannel. The system is equilibrated in the fluid phase close to the triple point at which gas,…

软凝聚态物质 · 物理学 2017-03-31 Madhu Priya , Yitzhak Rabin

The interplay of membrane proteins is vital for many biological processes, such as cellular transport, cell division, and signal transduction between nerve cells. Theoretical considerations have led to the idea that the membrane itself…

软凝聚态物质 · 物理学 2016-11-28 Casper van der Wel , Afshin Vahid , Anđela Šarić , Timon Idema , Doris Heinrich , Daniela J. Kraft

We construct a model to explore the hydrodynamic interactions of active inclusions in curved biological membranes. The curved membrane is modelled as a two dimensional layer of highly viscous fluid, surrounded by external solvents of…

软凝聚态物质 · 物理学 2025-06-23 Sarthak Bagaria , Rickmoy Samanta

A cell membrane can be simply regarded as composite material consisting of lipid bilayer, membrane cytoskeleton beneath lipid bilayer, and proteins embedded in lipid bilayer and linked with membrane cytoskeleton if one only concerns its…

其他定量生物学 · 定量生物学 2007-06-26 Z. C. Tu , R. An , Z. C. Ou-Yang

The mechanical effects of membrane compositional inhomogeneities are analyzed in a process analogous of neck formation in cellular membranes. We cast on the Canham-Helfrich model of fluid membranes with both the spontaneous curvature and…

软凝聚态物质 · 物理学 2022-03-30 G. Torres-Vargas , F. Monroy , J. A. Santiago

We review recent computer simulation studies of undulating lipid bilayers. Theoretical interpretations of such fluctuating membranes are most commonly based on generalized Helfrich-type elastic models, with additional contributions of local…

生物物理 · 物理学 2013-09-03 Friederike Schmid

Diffusion preserves the positivity of concentrations, therefore, multicomponent diffusion should be nonlinear if there exist non-diagonal terms. The vast variety of nonlinear multicomponent diffusion equations should be ordered and special…

材料科学 · 物理学 2015-03-17 A. N. Gorban , H. P. Sargsyan , H. A. Wahab

We develop theory and computational methods to investigate particle inclusions embedded within curved lipid bilayer membranes. We consider the case of spherical lipid vesicles where inclusion particles are coupled through (i) intramembrane…

软凝聚态物质 · 物理学 2023-02-28 Jon Karl Sigurdsson , Paul J. Atzberger

Adsorption of proteins onto membranes can alter the local membrane curvature. This phenomenon has been observed in biological processes such as endocytosis, tubulation and vesiculation. However, it is not clear how the local surface…

细胞行为 · 定量生物学 2016-04-28 Padmini Rangamani , Kranthi Kiran Mandadapu , George Oster

Interactions mediated by the cell membrane between inclusions, such as membrane proteins or antimicrobial peptides, play important roles in their biological activity. They also constitute a fascinating challenge for physicists, since they…

生物物理 · 物理学 2019-03-15 Anne-Florence Bitbol , Doru Constantin , Jean-Baptiste Fournier

By performing molecular dynamics simulations with up to 132 million coarse-grained particles in half-micron sized boxes, we show that hydrodynamics quantitatively explains the finite-size effects on diffusion of lipids, proteins, and carbon…

软凝聚态物质 · 物理学 2018-07-04 Martin Vögele , Jürgen Köfinger , Gerhard Hummer

We formulate a model for the dynamic growth of a membrane developing in a flow as the result of a precipitation reaction, a situation inspired by recent microfluidic experiments. The precipitating solid introduces additional forces on the…

流体动力学 · 物理学 2020-03-18 P. S. Eastham , M. N. J. Moore , N. G. Cogan , Q. Wang , O. Steinbock