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The identification of sets of co-regulated genes that share a common function is a key question of modern genomics. Bayesian profile regression is a semi-supervised mixture modelling approach that makes use of a response to guide inference…

Joinpoint regression is used to determine the number of segments needed to adequately explain the relationship between two variables. This methodology can be widely applied to real problems, but we focus on epidemiological data, the main…

应用统计 · 统计学 2011-12-08 Miguel A. Martinez-Beneito , Gonzalo García-Donato , Diego Salmerón

Benchmark dose (BMD; a dose associated with a specified change in response) is used to determine the point of departure for the acceptable daily intake of substances for humans. Multiple dose-response relationship models are considered in…

统计计算 · 统计学 2025-05-13 Sota Minewaki , Tomohiro Ohigashi , Takashi Sozu

In this article, we propose a novel spatial global-local spike-and-slab selection prior for image-on-scalar regression. We consider a Bayesian hierarchical Gaussian process model for image smoothing, that uses a flexible Inverse-Wishart…

统计方法学 · 统计学 2022-12-19 Zijian Zeng , Meng Li , Marina Vannucci

We analyze the best achievable performance of Bayesian learning under generative models by defining and upper-bounding the minimum excess risk (MER): the gap between the minimum expected loss attainable by learning from data and the minimum…

机器学习 · 计算机科学 2022-01-04 Aolin Xu , Maxim Raginsky

A Bayesian analytics framework that precisely quantifies uncertainty offers a significant advance for financial risk management. We develop an integrated approach that consistently enhances the handling of risk in market volatility…

We tackle the problem of multiscale regression for predictors that are spatially or temporally indexed, or with a pre-specified multiscale structure, with a Bayesian modular approach. The regression function at the finest scale is expressed…

统计方法学 · 统计学 2018-09-18 Michele Peruzzi , David B. Dunson

In this work we present a spatial approach to model and investigate mortality data referenced over a Lexis structure. We decompose the force of mortality into two interpretable components: a Markov random field, smooth with respect to time,…

应用统计 · 统计学 2018-10-23 Fabio Divino , Denekew Bitew Belay , Nico Keilman , Arnoldo Frigessi

A significant level of stigma and inequality exists in mental healthcare, especially in under-served populations. Inequalities are reflected in the data collected for scientific purposes. When not properly accounted for, machine learning…

Mortality patterns at a subnational level or across subpopulations are often used to examine the health of a population. In small populations, however, death counts are erratic. To deal with this problem, demographers have proposed…

统计方法学 · 统计学 2023-03-21 Esther Denecke , Pavel Grigoriev , Roland Rau

Climate models are limited by heavy computational costs, often producing outputs at coarse spatial resolutions, while many climate change impact studies require finer scales. Statistical downscaling bridges this gap, and we adapt the…

机器学习 · 计算机科学 2025-11-06 Maryam Alipourhajiagha , Pierre-Louis Lemaire , Youssef Diouane , Julie Carreau

Parameter estimation in diffusion processes from discrete observations up to a first-hitting time is clearly of practical relevance, but does not seem to have been studied so far. In neuroscience, many models for the membrane potential…

概率论 · 数学 2014-03-06 Enrico Bibbona , Susanne Ditlevsen

Selective Classification, wherein models can reject low-confidence predictions, promises reliable translation of machine-learning based classification systems to real-world scenarios such as clinical diagnostics. While current evaluation of…

High-frequency mortality data have attracted growing attention, but their use has largely been confined to specific applications rather than general modelling and forecasting. Such data pose new challenges to traditional mortality models…

应用统计 · 统计学 2026-05-14 Ziting Miao , Han Li , Yuyu Chen

The Intensive Care Unit (ICU) is a hospital department where machine learning has the potential to provide valuable assistance in clinical decision making. Classical machine learning models usually only provide point-estimates and no…

机器学习 · 计算机科学 2024-07-26 David Ruhe , Giovanni Cinà , Michele Tonutti , Daan de Bruin , Paul Elbers

While COVID-19 has resulted in a significant increase in global mortality rates, the impact of the pandemic on mortality from other causes remains uncertain. To gain insight into the broader effects of COVID-19 on various causes of death,…

应用统计 · 统计学 2024-09-05 Wei Zhang , Antonietta Mira , Ernst C. Wit

This study aims to understand the factors that resulted in under-five children's malnutrition from the Multiple Indicator Cluster (MICS-2019) nationwide surveys and classify different malnutrition stages based on the four well-established…

机器学习 · 计算机科学 2024-12-10 Tasfin Mahmud , Tayab Uddin Wara , Chironjeet Das Joy

In this paper, we discuss the impact of some mortality data anomalies on an internal model capturing longevity risk in the Solvency 2 framework. In particular, we are concerned with abnormal cohort effects such as those for generations 1919…

风险管理 · 定量金融 2020-09-02 Fabrice Balland , Alexandre Boumezoued , Laurent Devineau , Marine Habart , Tom Popa

We study Bayesian linear regression models with skew-symmetric scale mixtures of normal error distributions. These kinds of models can be used to capture departures from the usual assumption of normality of the errors in terms of heavy…

应用统计 · 统计学 2016-01-12 Francisco J. Rubio , Marc G. Genton

Event datasets including those provided by Uppsala Conflict Data Program (UCDP) are based on reports from the media and international organizations, and are likely to suffer from reporting bias. Since the UCDP has strict inclusion criteria,…

统计方法学 · 统计学 2024-09-16 Paola Vesco , David Randahl , Håvard Hegre , Stina Högbladh , Mert Can Yilmaz
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