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Studying systems where many individual bodies in motion interact with one another is a complex and interesting area. Simple mechanisms that may be determined for biological, chemical, or physical reasons can lead to astonishingly complex…

定量方法 · 定量生物学 2023-01-03 Cameron McNamee , Renee Reijo Pera

Conventional analysis of in vitro assays of motor proteins rests on the assumption that all proteins with the same chemical composition function identically; however molecule-to-molecule variation is often seen even in well-controlled…

We study the efficiency at the maximal power $\eta_\mathrm{max}$ of a finite-time Carnot cycle of a weakly interacting gas which we can reagard as a nearly ideal gas. In several systems interacting with the hot and cold reservoirs of the…

统计力学 · 物理学 2008-09-13 Yuki Izumida , Koji Okuda

Motor-driven intracellular transport of organelles, vesicles, and other molecular cargo is a highly collective process. An individual cargo is often pulled by a team of transport motors, with numbers ranging from only a few to several…

统计力学 · 物理学 2022-01-06 Matthew P. Leighton , David A. Sivak

Motor proteins are key players in intracellular transport processes and biological motion. Theoretical modeling of these systems has been achieved by the use of step processes on one-dimensional lattices. After a comprehensive introduction…

统计力学 · 物理学 2007-05-23 Hauke Hinsch , Roger Kouyos , Erwin Frey

The transport of cargo particles which are pulled by several molecular motors in a cooperative manner is studied theoretically. The transport properties depend primarily on the maximal number, $N$, of motor molecules that may pull…

亚细胞过程 · 定量生物学 2007-05-23 Stefan Klumpp , Reinhard Lipowsky

Experience collected in mesoscopic dynamic modeling of externally driven systems indicates absence of potentials that could play role of equilibrium or nonequilibrium thermodynamic potentials yet their thermo-dynamics-like modeling is often…

统计力学 · 物理学 2017-02-01 Miroslav Grmela

In cells and in vitro assays the number of motor proteins involved in biological transport processes is far from being unlimited. The cytoskeletal binding sites are in contact with the same finite reservoir of motors (either the cytosol or…

亚细胞过程 · 定量生物学 2014-09-26 Luca Ciandrini , I. Neri , Jean-Charles Walter , O. Dauloudet , A. Parmeggiani

The cytoskeleton is an active composite of filamentous proteins that dictates diverse mechanical properties and processes in eukaryotic cells by generating forces and autonomously restructuring itself. Enzymatic motors that act on the…

Intracellular transport based on molecular motors and its regulation are crucial to the functioning of cells. Filamentary tracks of the cells are abundantly decorated with non-motile microtubule-associated proteins, such as tau. Motivated…

生物物理 · 物理学 2015-06-15 J. Sparacino , M. G. Farías , P. W. Lamberti

The understanding of memory effects arising from the interaction between system and environment is a key for engineering quantum thermodynamic devices beyond the standard Markovian limit. We study the performance of measurement-based…

量子物理 · 物理学 2020-01-14 Obinna Abah , Mauro Paternostro

Active particles driven by colored noise can be approximately mapped onto a system that obeys detailed balance. The effective interactions which can be derived for such a system allow to describe the structure and phase behavior of the…

软凝聚态物质 · 物理学 2017-11-30 René Wittmann , Umberto Marini Bettolo Marconi , Claudio Maggi , Joseph M. Brader

There are many processes in biology in which mechanical forces are generated. Force-bearing networks can transduce locally developed mechanical signals very extensively over different parts of the cell or tissues. In this article we conduct…

生物大分子 · 定量生物学 2009-11-13 Francesco Valle , Massimo Sandal , Bruno Samorí

The laws of thermodynamics strongly restrict the performance of thermal machines. Standard thermodynamics, initially developed for uncorrelated macroscopic systems, does not hold for microscopic systems correlated with their environments.…

量子物理 · 物理学 2025-11-13 Milton Aguilar , Eric Lutz

We have developed a two dimensional stochastic molecular dynamics model for the description of intra cellular collective motion of bio motors, in particular Kinesins, on a microtubular track. The model is capable or reproducing the…

软凝聚态物质 · 物理学 2010-06-22 Yousef Jamali , M. Ebrahim Foulaadvand , H. Rafii Tabar

We want to understand whether and to which extent the maximal (Carnot) efficiency for heat engines can be reached at a finite power. To this end we generalize the Carnot cycle so that it is not restricted to slow processes. We show that for…

Human-created engines and evolutionarily optimized molecular motors exhibit sophisticated design in order to harvest chemical or thermal energy for generating unidirectional motion. The complexity of these motors makes their random…

统计力学 · 物理学 2017-05-10 Alexander Feigel , Asaf Rozen

Properties of transport of molecular motors are investigated. A simplified model based on the concept of Brownian ratchets is applied. We analyze a stochastic equation of motion by means of numerical methods. The transport is systematically…

统计力学 · 物理学 2011-12-07 Lukasz Machura , Marcin Kostur , Jerzy Luczka

Adaptive systems -- such as a biological organism gaining survival advantage, an autonomous robot executing a functional task, or a motor protein transporting intracellular nutrients -- must model the regularities and stochasticity in their…

统计力学 · 物理学 2021-04-13 A. B. Boyd , J. P. Crutchfield , M. Gu

Thermodynamics places a limit on the efficiency of heat engines, but not on their output power or on how the power and efficiency change with the engine's cycle time. In this manuscript, we develop a geometrical description of the power and…

统计力学 · 物理学 2016-08-06 Oren Raz , Yigit Subaşı , Rami Pugatch