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Cancer is one of the most feared diseases in the world it has increased disturbingly and breast cancer occurs in one out of eight women, the prediction of malignancies plays essential roles not only in revealing human genome, but also in…

计算工程、金融与科学 · 计算机科学 2013-03-05 Ayad Ghany Ismaeel , Anar Auda Ablahad

Despite significant medical advancements, cancer remains the second leading cause of death, with over 600,000 deaths per year in the US. One emerging field, pathway analysis, is promising but still relies on manually derived wet lab data,…

机器学习 · 计算机科学 2025-09-17 Rishab Parthasarathy , Achintya Bhowmik

Tumor protein P53 is believed to be involved in over half of human cancers cases, the prediction of malignancies plays essential roles not only in advance detection for cancer, but also in discovering effective prevention and treatment of…

计算工程、金融与科学 · 计算机科学 2013-10-09 Ayad Ghany Ismaeel

Non-synonymous single nucleotide polymorphisms (nsSNPs) are single nucleotide substitution occurring in the coding region of a gene and leads to a change in amino-acid sequence of protein. The studies have shown these variations may be…

In healthcare, it is essential to explain the decision-making process of machine learning models to establish the trustworthiness of clinicians. This paper introduces BI-RADS-Net, a novel explainable deep learning approach for cancer…

计算机视觉与模式识别 · 计算机科学 2021-10-11 Boyu Zhang , Aleksandar Vakanski , Min Xian

This research is to search for alternatives to the resolution of complex medical diagnosis where human knowledge should be apprehended in a general fashion. Successful application examples show that human diagnostic capabilities are…

神经与进化计算 · 计算机科学 2010-09-28 S. M. Kamruzzaman , Ahmed Ryadh Hasan , Abu Bakar Siddiquee , Md. Ehsanul Hoque Mazumder

Invasive ductal carcinoma is a prevalent, potentially deadly disease associated with a high rate of morbidity and mortality. Its malignancy is the second leading cause of death from cancer in women. The mammogram is an extremely useful…

计算机视觉与模式识别 · 计算机科学 2021-11-09 Rushabh Patel

Diagnosis of breast cancer has been well studied in the past. Multiple linear programming models have been devised to approximate the relationship between cell features and tumour malignancy. However, these models are less capable in…

机器学习 · 计算机科学 2020-02-21 Ke Quan

Cancer is a term that denotes a group of diseases caused by abnormal growth of cells that can spread in different parts of the body. According to the World Health Organization (WHO), cancer is the second major cause of death after…

机器学习 · 计算机科学 2023-01-31 Fadi Alharbi , Aleksandar Vakanski

In practice, histopathological diagnosis of tumor malignancy often requires a human expert to scan through histopathological images at multiple magnification levels, after which a final diagnosis can be accurately determined. However,…

计算机视觉与模式识别 · 计算机科学 2019-05-29 Qicheng Lao , Thomas Fevens

Identifying the mutations that drive cancer growth is key in clinical decision making and precision oncology. As driver mutations confer selective advantage and thus have an increased likelihood of occurrence, frequency-based statistical…

基因组学 · 定量生物学 2021-05-04 Adnan Akbar , Andrey Solovyev , John W Cassidy , Nirmesh Patel , Harry W Clifford

Cancer progression and monotonic accumulation models were developed to discover dependencies in the irreversible acquisition of binary traits from cross-sectional data. They have been used in computational oncology and virology but also in…

种群与进化 · 定量生物学 2025-05-12 Ramon Diaz-Uriarte , Iain G. Johnston

The prediction plays the important role in detecting efficient protection and therapy of cancer. The prediction of mutations in gene needs a diagnostic and classification, which is based on the whole database (big dataset), to reach…

机器学习 · 计算机科学 2016-08-10 Ayad Ghany Ismaeel , Dina Yousif Mikhail

It is imperative that breast cancer is detected precisely and timely to improve patient outcomes. Diagnostic methodologies have traditionally relied on unimodal approaches; however, medical data analytics is integrating diverse data sources…

机器学习 · 计算机科学 2024-06-21 Faseela Abdullakutty , Younes Akbari , Somaya Al-Maadeed , Ahmed Bouridane , Rifat Hamoudi

Accurate identification of breast cancer types plays a critical role in guiding treatment decisions and improving patient outcomes. This paper presents an artificial intelligence enabled tool designed to aid in the identification of breast…

图像与视频处理 · 电气工程与系统科学 2025-05-28 Neil Chaudhary , Zaynah Dhunny

A mutation in a protein-coding gene in DNA can alter the protein structure coded by the same gene. Structurally altered proteins usually lose their functions and sometimes gain an undesirable function instead. These types of mutations and…

定量方法 · 定量生物学 2017-08-29 Kaan Aygen , Berkay Celik , Umut Eser

Over the last decades, many prognostic models based on artificial intelligence techniques have been used to provide detailed predictions in healthcare. Unfortunately, the real-world observational data used to train and validate these models…

机器学习 · 计算机科学 2023-11-21 Alice Bernasconi , Alessio Zanga , Peter J. F. Lucas , Marco Scutari , Fabio Stella

Automatic detection of brain neoplasm in Magnetic Resonance Imaging (MRI) is gaining importance in many medical diagnostic applications. This report presents two improvements for brain neoplasm detection in MRI data: an advanced…

计算机视觉与模式识别 · 计算机科学 2021-01-26 Nilanjan Sinhababu , Monalisa Sarma , Debasis Samanta

Identifying the genes and mutations that drive the emergence of tumors is a major step to improve understanding of cancer and identify new directions for disease diagnosis and treatment. Despite the large volume of genomics data, the…

机器学习 · 计算机科学 2022-04-05 Renan Andrades , Mariana Recamonde-Mendoza

Breast cancer is still the second top cause of cancer deaths worldwide and this emphasizes the importance of necessary steps for early detection. Traditional diagnostic methods, such as mammography, ultrasound, and thermography, which have…

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