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Chemical plant design and optimisation have proven challenging due to the complexity of these real-world systems. The resulting complexity translates into high computational costs for these systems' mathematical formulations and simulation…

神经与进化计算 · 计算机科学 2022-04-28 Liezl Stander , Matthew Woolway , Terence L. Van Zyl

Evaluating treatment effects is critical in clinical trials but sometimes involves lengthy, invasive, or costly follow-up procedures. In these cases, surrogate markers, which provide intermediate measures of the long-term treatment effect,…

统计方法学 · 统计学 2026-03-24 Sarah C. Lotspeich , P. D. Anh. Nguyen , Layla Parast

We combine two important ideas in the analysis of large-scale genomics experiments (e.g. experiments that aim to identify genes that are differentially expressed between two conditions). The first is use of Empirical Bayes (EB) methods to…

统计方法学 · 统计学 2026-02-02 David Gerard , Matthew Stephens

A crucial task for a randomized controlled trial (RCT) is to specify a statistical method that can yield an efficient estimator and powerful test for the treatment effect. A novel and effective strategy to obtain efficient and powerful…

Estimating causal effects from observational data is challenging, especially in the presence of latent confounders. Much work has been done on addressing this challenge, but most of the existing research ignores the bias introduced by the…

机器学习 · 计算机科学 2024-08-15 Yang Xie , Ziqi Xu , Debo Cheng , Jiuyong Li , Lin Liu , Yinghao Zhang , Zaiwen Feng

Prognostic covariate adjustment (PROCOVA) is a two-sample two-stage estimation method used in randomized controlled trials. In the first stage, a prognostic score, defined as the conditional expectation of an outcome given covariates under…

统计方法学 · 统计学 2026-05-01 Nodoka Seya , Masataka Taguri

Diffusion models have become emerging generative models. Their sampling process involves multiple steps, and in each step the models predict the noise from a noisy sample. When the models make prediction, the output deviates from the ground…

机器学习 · 计算机科学 2025-10-28 Shifeng Xu , Yanzhu Liu , Adams Wai-Kin Kong

When evaluating the efficacy of social programs and medical treatments using randomized experiments, the estimated overall average causal effect alone is often of limited value and the researchers must investigate when the treatments do and…

应用统计 · 统计学 2013-05-27 Kosuke Imai , Marc Ratkovic

In many empirical settings, directly observing a treatment variable may be infeasible although an error-prone surrogate measurement of the latter will often be available. Causal inference based solely on the surrogate measurement is…

统计方法学 · 统计学 2024-09-26 Ying Zhou , Eric Tchetgen Tchetgen

Detrended fluctuation analysis (DFA) [1] of the volatility series has been found to be useful in dentifying possible nonlinear/multifractal dynamics in the empirical sample [2-4]. Long-range volatile correlation can be an outcome of static…

数据分析、统计与概率 · 物理学 2009-11-11 Radhakrishnan Nagarajan

Many conventional statistical and machine learning methods face challenges when applied directly to high dimensional temporal observations. In recent decades, Functional Data Analysis (FDA) has gained widespread popularity as a framework…

统计方法学 · 统计学 2024-10-01 Donato Riccio , Fabrizio Maturo , Elvira Romano

Oilfield development related decisions are made using reservoir simulation-based optimization study in which different production scenarios and well controls are compared. Such simulations are computationally expensive and so surrogate…

机器学习 · 计算机科学 2022-03-01 Ajitabh Kumar

In this paper we study a family of variance reduction methods with randomized batch size---at each step, the algorithm first randomly chooses the batch size and then selects a batch of samples to conduct a variance-reduced stochastic…

机器学习 · 计算机科学 2018-08-08 Xuanqing Liu , Cho-Jui Hsieh

Test-Time adaptation (TTA) aims to enhance model robustness against distribution shifts through rapid model adaptation during inference. While existing TTA methods often rely on entropy-based unsupervised training and achieve promising…

计算机视觉与模式识别 · 计算机科学 2025-05-08 Zixuan Hu , Yichun Hu , Ling-Yu Duan

Machine learning models play a vital role in time series forecasting. These models, however, often overlook an important element: point uncertainty estimates. Incorporating these estimates is crucial for effective risk management, informed…

机器学习 · 计算机科学 2024-09-11 Leonid Erlygin , Vladimir Zholobov , Valeriia Baklanova , Evgeny Sokolovskiy , Alexey Zaytsev

Covariate shift has been shown to sharply degrade both predictive accuracy and the calibration of uncertainty estimates for deep learning models. This is worrying, because covariate shift is prevalent in a wide range of real world…

机器学习 · 计算机科学 2021-01-18 Zachary Nado , Shreyas Padhy , D. Sculley , Alexander D'Amour , Balaji Lakshminarayanan , Jasper Snoek

Compact Genetic Algorithms (cGAs) are condensed variants of classical Genetic Algorithms (GAs) that use a probability vector representation of the population instead of the complete population. cGAs have been shown to significantly reduce…

神经与进化计算 · 计算机科学 2025-04-07 Prasanta Dutta , Anirban Mukhopadhyay

Sample-average approximations (SAA) are a practical means of finding approximate solutions of stochastic programming problems involving an extremely large (or infinite) number of scenarios. SAA can also be used to find estimates of a lower…

其他统计学 · 统计学 2014-05-08 Jiajie Chen , Cong Han Lim , Peter Z. G. Qian , Jeff Linderoth , Stephen J. Wright

Can we evolve better training data for machine learning algorithms? To investigate this question we use population-based optimisation algorithms to generate artificial surrogate training data for naive Bayes for regression. We demonstrate…

人工智能 · 计算机科学 2018-11-29 Michael Mayo , Eibe Frank

The spatial error model (SEM) is a type of simultaneous autoregressive (SAR) model for analysing spatially correlated data. Markov chain Monte Carlo (MCMC) is one of the most widely used Bayesian methods for estimating SEM, but it has…

统计方法学 · 统计学 2024-06-14 Anjana Wijayawardhana , David Gunawan , Thomas Suesse