相关论文: Parameter space exploration of ecological models
The basic mechanics of evolution have been understood since Darwin. But debate continues over whether macroevolutionary phenomena are driven primary by the fitness structure of genotype space or by ecological interaction. In this paper we…
Configurational entropy is an important factor in the free energy change of many macromolecular recognition and binding processes, and has been intensively studied. Despite great progresses that have been made, the global sampling remains…
Statistical and mathematical modeling are crucial to describe, interpret, compare and predict the behavior of complex biological systems including the organization of hematopoietic stem and progenitor cells in the bone marrow environment.…
In ecological studies niche overlap is often used to quantify species interaction and dynamics. This paper develops a robust, nonparametric statistical framework for quantifying and analyzing multivariate niche overlap. Parametric methods…
Natural ecosystems are characterized by striking diversity of form and functions and yet exhibit deep symmetries emerging across scales of space, time and organizational complexity. Species-area relationships and species-abundance…
Simplified representations of macromolecules help in rationalising and understanding the outcome of atomistic simulations, and serve to the construction of effective, coarse-grained models. The number and distribution of coarse-grained…
Dynamic models are widely used to mathematically describe biological phenomena that evolve over time. One important area of application is leukaemia research, where leukaemia cells are genetically modified in preclinical studies to explore…
Measurement is a fundamental building block of numerous scientific models and their creation. This is in particular true for data driven science. Due to the high complexity and size of modern data sets, the necessity for the development of…
Mappings to structured output spaces (strings, trees, partitions, etc.) are typically learned using extensions of classification algorithms to simple graphical structures (eg., linear chains) in which search and parameter estimation can be…
Demands on the disaster response capacity of the European Union are likely to increase, as the impacts of disasters continue to grow both in size and frequency. This has resulted in intensive research on issues concerning spatially-explicit…
A substantial gap persists in understanding the reasons behind the exceptional performance of the Transformer architecture in NLP. A particularly unexplored area involves the mechanistic description of how the distribution of parameters…
Constraining Beyond the Standard Model theories usually involves scanning highly multi-dimensional parameter spaces and check observable predictions against experimental bounds and theoretical constraints. Such task is often timely and…
The exponential growth of text-based data in domains such as healthcare, education, and social sciences has outpaced the capacity of traditional qualitative analysis methods, which are time-intensive and prone to subjectivity. Large…
Genomics methods have uncovered patterns in a range of biological systems, but obscure important aspects of cell behavior: the shape, relative locations of, movement of, and interactions between cells in space. Spatial technologies that…
The aim of this paper is to explore and develop advanced spatial Bayesian assessment methods and techniques for land use modeling. The paper provides a comprehensive guide for assessing additional informational entropy value of model…
Accurate and comprehensive measurements of a range of sustainable development outcomes are fundamental inputs into both research and policy. We synthesize the growing literature that uses satellite imagery to understand these outcomes, with…
We develop an efficient estimation procedure for identifying and estimating the central subspace. Using a new way of parameterization, we convert the problem of identifying the central subspace to the problem of estimating a finite…
Discrete time, spatially extended models play an important role in ecology, modelling population dynamics of species ranging from micro-organisms to birds. An important question is how 'bottom up', individual-based models can be…
We present a collection of new, open-source computational tools for numerically modeling recent large-scale observational data sets using modern cosmology theory. Specifically, these tools will allow both students and researchers to…
1. Theoretical models pertaining to feedbacks between ecological and evolutionary processes are prevalent in multiple biological fields. An integrative overview is currently lacking, due to little crosstalk between the fields and the use of…