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相关论文: Semiparametric theory for causal mediation analysi…

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We discuss causal mediation analyses for survival data and propose a new approach based on the additive hazards model. The emphasis is on a dynamic point of view, that is, understanding how the direct and indirect effects develop over time.…

Often linear regression is used to perform mediation analysis. However, in many instances, the underlying relationships may not be linear, as in the case of placental-fetal hormones and fetal development. Although, the exact functional form…

统计方法学 · 统计学 2023-10-16 Qing Yin , Jong-Hyeon Jeong , Xu Qin , Shyamal D Peddada , Jennifer Adibi

Mediation analysis is difficult when the number of potential mediators is larger than the sample size. In this paper we propose new inference procedures for the indirect effect in the presence of high-dimensional mediators for linear…

统计方法学 · 统计学 2019-10-29 Ruixuan Rachel Zhou , Liewei Wang , Sihai Dave Zhao

Electronic health records and other sources of observational data are increasingly used for drawing causal inferences. The estimation of a causal effect using these data not meant for research purposes is subject to confounding and…

统计方法学 · 统计学 2023-04-19 Janie Coulombe , Shu Yang

Mediation analysis is appealing for its ability to improve understanding of the mechanistic drivers of causal effects, but real-world data complexities challenge its successful implementation, including: 1) the existence of post-exposure…

统计方法学 · 统计学 2022-12-19 Kara E Rudolph , Nicholas Williams , Ivan Diaz

We consider a semiparametric generalized linear model and study estimation of both marginal and quantile effects in this model. We propose an approximate maximum likelihood estimator, and rigorously establish the consistency, the asymptotic…

统计方法学 · 统计学 2022-04-06 Seong-ho Lee , Yanyuan Ma , Elvezio Ronchetti

We consider causal models with two observed variables and one latent variables, each variable being discrete, with the goal of characterizing the possible distributions on outcomes that can result from controlling one of the observed…

信息论 · 计算机科学 2021-03-05 Kevin Shu

Evaluating the causal health effects of multivariate, continuous exposures, such as air pollution mixtures, is a critical public health challenge. A primary obstacle is the frequent violation of the positivity assumption, which renders the…

统计方法学 · 统计学 2026-05-05 Zhuochao Huang , Kejin Dong , Tuo Lin , Joseph Antonelli

Mediation analysis draws increasing attention in many scientific areas such as genomics, epidemiology and finance. In this paper, we propose new statistical inference procedures for high dimensional mediation models, in which both the…

统计方法学 · 统计学 2021-08-30 Xu Guo , Runze Li , Jingyuan Liu , Mudong Zeng

In many applications of causal inference, the treatment received by one unit may influence the outcome of another, a phenomenon referred to as interference. Although there are several frameworks for conducting causal inference in the…

统计方法学 · 统计学 2025-11-27 Matvey Ortyashov , AmirEmad Ghassami

Externally controlled trials are crucial in clinical development when randomized controlled trials are unethical or impractical. These trials consist of a full treatment arm with the experimental treatment and a full external control arm.…

统计方法学 · 统计学 2025-03-11 Chenyin Gao , Xiang Zhang , Shu Yang

Empirical researchers are often interested in not only whether a treatment affects an outcome of interest, but also how the treatment effect arises. Causal mediation analysis provides a formal framework to identify causal mechanisms through…

计量经济学 · 经济学 2022-02-01 Bora Kim

Causal effect estimation under networked interference is an important but challenging problem. Available parametric methods are limited in their model space, while previous semiparametric methods, e.g., leveraging neural networks to fit…

机器学习 · 计算机科学 2025-02-27 Weilin Chen , Ruichu Cai , Zeqin Yang , Jie Qiao , Yuguang Yan , Zijian Li , Zhifeng Hao

In observational studies, the identification of causal estimands depends on the no unmeasured confounding (NUC) assumption. As this assumption is not testable from observed data, sensitivity analysis plays an important role in observational…

统计方法学 · 统计学 2023-09-28 Md Abdul Basit , Mahbub A. H. M. Latif , Abdus S Wahed

When drawing causal inference from observational data, there is always concern about unmeasured confounding. One way to tackle this is to conduct a sensitivity analysis. One widely-used sensitivity analysis framework hypothesizes the…

统计方法学 · 统计学 2022-06-22 Bo Zhang , Eric J. Tchetgen Tchetgen

In social science researches, causal inference regarding peer effects often faces significant challenges due to homophily bias and contextual confounding. For example, unmeasured health conditions (e.g., influenza) and psychological states…

统计方法学 · 统计学 2025-04-29 Shanshan Luo , Kang Shuai , Yechi Zhang , Wei Li , Yangbo He

Traditional mediation analysis typically examines the relations among an intervention, a time-invariant mediator, and a time-invariant outcome variable. Although there may be a direct effect of the intervention on the outcome, there is a…

应用统计 · 统计学 2020-08-28 Xizhen Cai , Donna L. Coffman , Megan E. Piper , Runze Li

Causal inference is a critical research area with multi-disciplinary origins and applications, ranging from statistics, computer science, economics, psychology to public health. In many scientific research, randomized experiments provide a…

统计方法学 · 统计学 2022-07-26 Jingying Zeng

Assessing the causal effects of interventions on ordinal outcomes is an important objective of many educational and behavioral studies. Under the potential outcomes framework, we can define causal effects as comparisons between the…

统计方法学 · 统计学 2018-04-06 Jiannan Lu , Peng Ding , Tirthankar Dasgupta

Causal mediation analysis is a powerful tool in environmental health research, allowing researchers to uncover the pathways through which exposures influence health outcomes. While traditional mediation methods have been widely applied to…