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Multiphoton microscopy has enabled us to image cellular dynamics in vivo. However, the excitation wavelength for imaging with commercially available lasers is mostly limited between 650-1040 nm. Here we develop a femtosecond fiber laser…

Following the recent developement of Fourier ptychographic microscopy (FPM) in the visible range by Zheng et al. (2013), we propose an adaptation for hard x-rays. FPM employs ptychographic reconstruction to merge a series of low-resolution,…

仪器与探测器 · 物理学 2016-09-27 H. Simons , H. F. Poulsen , J. P. Guigay , C. Detlefs

Fourier ptychography microscopy (FPM), sharing its roots with synthetic aperture technique and phase retrieval method, is a recently developed computational microscopic super-resolution technique. By turning on the light-emitting diode…

光学 · 物理学 2021-05-07 G. Zhou , S. Zhang , C. Zheng , T. Li , Y. Hu , Q. Hao

An ultrafast single-pixel optical 2D imaging system using a single multimode fiber (MF) is proposed. The MF acted as the all-optical random pattern generator. Light with different wavelengths pass through a single MF will generator…

We report a compact, cost-effective and field-portable lensless imaging platform for quantitative microscopy. In this platform, the object is placed on top of an image sensor chip without using any lens. We use a low-cost galvo scanner to…

图像与视频处理 · 电气工程与系统科学 2019-04-26 He Zhang , Zichao Bian , Shaowei Jiang , Jian Liu , Pengming Song , Guoan Zheng

Light-field microscopy represents a promising solution for microscopic volumetric imaging, thanks to its capability to encode information on multiple planes in a single acquisition. This is achieved through its peculiar simultaneous capture…

We report a simple single-pixel imaging system with a low mean squared error in the entire terahertz frequency region (3-13 THz) that employs a thin metallic ring with a series of directly perforated random masks and a subpixel mask…

光学 · 物理学 2020-10-28 Adam Vallés , Jiahuan He , Seigo Ohno , Takashige Omatsu , Katsuhiko Miyamoto

Lensless imaging enables exceptionally compact fluorescence sensors, advancing applications in \textit{in vivo} imaging and low-cost, point-of-care diagnostics. These sensors require a filter to block the excitation light while passing…

图像与视频处理 · 电气工程与系统科学 2026-02-20 Lukas Harris , Micah Roschelle , Jack Bartley , Mekhail Anwar

The development of optical fibers has revolutionized telecommunications by enabling long-distance broad-band transmission with minimal loss. In turn, the ubiquity of high-quality low-cost fibers enabled a number of additional applications,…

光学 · 物理学 2017-03-30 Brandon Redding , Mansoor Alam , Martin Seifert , Hui Cao

High-resolution wide field-of-view (FOV) microscopic imaging plays an essential role in various fields of biomedicine, engineering, and physical sciences. As an alternative to conventional lens-based scanning techniques, lensfree holography…

光学 · 物理学 2017-06-16 Jialin Zhang , Jiasong Sun , Qian Chen , Jiaji Li , Chao Zuo

The mathematical theory of compressed sensing (CS) asserts that one can acquire signals from measurements whose rate is much lower than the total bandwidth. Whereas the CS theory is now well developed, challenges concerning hardware…

Endoscopic optical imaging using a single multimode fiber (MMF) has emerged as a promising approach for highly compact, minimally invasive, and high-resolution imaging. Unlike conventional fiber bundles, MMF-based endomicroscopes exploit…

IR spectroscopy such as Fourier transform infrared spectroscopy (FTIR) are widely used for the investigation of structure and the quantitative determination of substances in the fields of chemistry, physics, biology, medicine, and…

We present our image processing system for the reduction of optical imaging data from multi-chip cameras. In the framework of the Garching Bonn Deep Survey (GaBoDS; Schirmer et al. 2003) consisting of about 20 square degrees of high-quality…

Light-field cameras allow the acquisition of both the spatial and angular components of the light. This has a wide range of applications from image refocusing to 3D reconstruction of a scene. The conventional way to perform such…

We demonstrate an electro-optic wide-field method to enable fluorescence lifetime microscopy (FLIM) with high throughput and single-molecule sensitivity. Resonantly driven Pockels cells are used to efficiently gate images at 39 MHz,…

光学 · 物理学 2021-09-23 Adam J. Bowman , Mark A. Kasevich

Mid-infrared hyperspectral imaging has become an indispensable tool to spatially resolve chemical information in a wide variety of samples. However, acquiring three-dimensional data cubes is typically time-consuming due to the limited speed…

光学 · 物理学 2026-05-29 Jianan Fang , Kun Huang , Ruiyang Qin , Yan Liang , E Wu , Ming Yan , Heping Zeng

Integrated photonic active beamforming can significantly reduce the size and cost of coherent imagers for LiDAR and medical imaging applications. In current architectures, the complexity of photonic and electronic circuitry linearly…

信号处理 · 电气工程与系统科学 2021-08-24 Aroutin Khachaturian , Reza Fatemi , Ali Hajimiri

Photoacoustic imaging can achieve high-resolution three-dimensional visualization of optical absorbers at penetration depths ~ 1 cm in biological tissues by detecting optically-induced high ultrasound frequencies. Tomographic acquisition…

光学 · 物理学 2015-05-15 Jérôme Gateau , Marc Gesnik , Jean-Marie Chassot , Emmanuel Bossy

Atomic Force Microscopy - Infrared (AFM-IR) spectroscopy allows spectroscopic studies in the mid-infrared spectral region with a spatial resolution better than 50 nm. We show that the high spatial resolution can be used to perform…

定量方法 · 定量生物学 2017-04-06 Luca Quaroni , Katarzyna Pogoda , Joanna-Wiltowska Zuber , Wojciech Kwiatek