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High resolution optical endoscopes are increasingly used in diagnosis of various medical conditions of internal organs, such as the gastrointestinal tracts, but they are too expensive for use in resource-poor settings. On the other hand,…

光学 · 物理学 2016-03-08 Xiangqian Hong , Vivek K. Nagarajan , Dale H. Mugler , Bing Yu

We present experimental demonstration of tilt-mirror assisted transmission structured illumination microscopy (tSIM) that offers a large field of view super resolution imaging. An assembly of custom-designed tilt-mirrors are employed as the…

LISA is a proposed low resolution (R~15-30) imaging spectrometer for SOFIA, the American-German Stratospheric Observatory for Far Infrared Astronomy. Covering the wavelength range from 40micron to 220micron with three channels, LISA…

天体物理学 · 物理学 2007-05-23 Alfred Krabbe , Juergen Wolf

Ultrasound-switchable fluorescence (USF) imaging was recently developed to overcome the limitation of the poor spatial resolution of the conventional fluorescence imaging in centimeter-deep tissue. However, in vivo USF imaging has not been…

生物物理 · 物理学 2018-10-12 Tingfeng Yao , Shuai Yu , Yang Liu , Baohong Yuan

We report the first computational super-resolved, multi-camera integral imaging at long-wave infrared (LWIR) wavelengths. A synchronized array of FLIR Lepton cameras was assembled, and computational super-resolution and integral-imaging…

光学 · 物理学 2017-08-14 Miguel A. Preciado , Guillem Carles , Andrew R. Harvey

High speed, high-resolution, and accurate 3D scanning would open doors to many new applications in graphics, robotics, science, and medicine by enabling the accurate scanning of deformable objects during interactions. Past attempts to use…

计算机视觉与模式识别 · 计算机科学 2025-10-23 Giancarlo Pereira , Yidan Gao , Yurii Piadyk , David Fouhey , Claudio T Silva , Daniele Panozzo

The resolution of optical imaging devices is ultimately limited by the diffraction of light. To circumvent this limit, modern super-resolution microscopy techniques employ active interaction with the object by exploiting its optical…

光学 · 物理学 2022-01-05 A. A. Pushkina , G. Maltese , J. I. Costa-Filho , P. Patel , A. I. Lvovsky

Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…

量子物理 · 物理学 2026-01-15 Alberto Paniate , Giuseppe Ortolano , Sarika Soman , Marco Genovese , Ivano Ruo-Berchera

Optical approaches to fluorescent, spectroscopic, and morphological imaging have made exceptional advances in the last decade. Super-resolution imaging and wide-field multiphoton imaging are now underpinning major advances across the…

This article presents a method to perform diffraction tomography in a standard microscope that includes an LED array for illumination. After acquiring a sequence of intensity-only images of a thick sample, a ptychography-based…

光学 · 物理学 2015-10-30 Roarke Horstmeyer , Changhuei Yang

Fluorescence imaging is indispensable to biology and neuroscience. The need for large-scale imaging in freely behaving animals has further driven the development in miniaturized microscopes (miniscopes). However, conventional microscopes /…

光学 · 物理学 2020-10-29 Yujia Xue , Ian G. Davison , David A. Boas , Lei Tian

We present an approach of utilizing a multi-camera array system for capturing dynamic high-resolution videos of the human face, with improved imaging performance as compared to traditional single-camera configurations. Employing an array of…

A miniaturized full-frequency encoded illumination (mini-FEI) chip is presented for high-throughput super-resolution imaging using the spatial frequency shift (SFS) effect. A tunable full SFS scheme is achieved through propagating and…

An increasing number of applications in computer vision, specially, in medical imaging and remote sensing, become challenging when the goal is to classify very large images with tiny informative objects. Specifically, these classification…

计算机视觉与模式识别 · 计算机科学 2021-12-07 Fanjie Kong , Ricardo Henao

Biological and biomedical samples are routinely examined using focused two-photon (2P) fluorescence microscopy due to its intrinsic axial sectioning and reduced out-of-focus bleaching. However, 2P imaging often requires excitation…

Fourier ptychographic microscopy (FPM) is a powerful computational imaging modality that achieves high space-bandwidth product imaging for biomedical samples. However, its adoption is limited by slow data acquisition due to the need for…

光学 · 物理学 2025-09-09 Shi Zhao , Haowen Zhou , Changhuei Yang

Multi-spectral imaging, which simultaneously captures the spatial and spectral information of a scene, is widely used across diverse fields, including remote sensing, biomedical imaging, and agricultural monitoring. Here, we introduce a…

The application of the non conventional imaging technique LOFI (Laser Optical Feedback Imaging) to coherent microscopy is presented. This simple and efficient technique using frequency-shifted optical feedback needs the sample to be scanned…

Autofocus (AF) methods are extensively used in biomicroscopy, for example to acquire timelapses, where the imaged objects tend to drift out of focus. AD algorithms determine an optimal distance by which to move the sample back into the…

图像与视频处理 · 电气工程与系统科学 2021-01-14 Adrian Shajkofci , Michael Liebling

Increasing demand for understanding the vast heterogeneity of cellular phenotypes has driven the development of imaging flow cytometry (IFC), that combines features of flow cytometry with fluorescence and bright field microscopy. IFC…

定量方法 · 定量生物学 2019-02-06 Yuanyuan Han , Rui Tang , Yi Gu , Alex Ce Zhang , Wei Cai , Violet Castor , Sung Hwan Cho , William Alaynick , Yu-Hwa Lo