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Brain aging is a widely studied longitudinal process throughout which the brain undergoes considerable morphological changes and various machine learning approaches have been proposed to analyze it. Within this context, brain age prediction…

计算机视觉与模式识别 · 计算机科学 2020-11-30 Matthias Wilms , Jordan J. Bannister , Pauline Mouches , M. Ethan MacDonald , Deepthi Rajashekar , Sönke Langner , Nils D. Forkert

Magnetoencephalography (MEG) is a cutting-edge neuroimaging technique that measures the intricate brain dynamics underlying cognitive processes with an unparalleled combination of high temporal and spatial precision. MEG data analytics has…

神经元与认知 · 定量生物学 2025-05-20 Arthur Dehgan , Hamza Abdelhedi , Vanessa Hadid , Irina Rish , Karim Jerbi

Experimental results in recent years have shown that adult neurogenesis is a significant phenomenon in the mammalian brain. Little is known, however, about the functional role played by the generation and destruction of neurons in the…

神经元与认知 · 定量生物学 2009-11-10 Guillermo A. Cecchi , Marcelo O. Magnasco

Cancer progresses with a change in the structure of the gene network in normal cells. We define a measure of organizational hierarchy in gene networks of affected cells in adult acute myeloid leukemia (AML) patients. With a retrospective…

组织与器官 · 定量生物学 2015-06-23 Shubham Tripathi , Michael W. Deem

Machine learning has rapidly evolved during the last decade, achieving expert human performance on notoriously challenging problems such as image classification. This success is partly due to the re-emergence of bio-inspired modern…

神经与进化计算 · 计算机科学 2023-08-08 Edgar Galván , Fergal Stapleton

The Epithelial Dysplasia (ED) is a tissue alteration commonly present in lesions preceding oral cancer, being its presence one of the most important factors in the progression toward carcinoma. This study proposes a method to design a low…

图像与视频处理 · 电气工程与系统科学 2022-04-08 Karoline da Rocha , José C. M. Bermudez , Elena R. C. Rivero , Márcio H. Costa

The mitosis process of an eukaryotic cell can be represented by the structure constants of an evolution algebra. Any isotopism of the latter corresponds to a mutation of genotypes of the former. This paper uses Computational Algebraic…

环与代数 · 数学 2019-01-08 Óscar J. Falcón , Raúl M. Falcón , Juan Núñez

Facial age estimation has achieved considerable success under controlled conditions. However, in unconstrained real-world scenarios, which are often referred to as 'in the wild', age estimation remains challenging, especially when faces are…

计算机视觉与模式识别 · 计算机科学 2026-01-21 Waqar Tanveer , Laura Fernández-Robles , Eduardo Fidalgo , Víctor González-Castro , Enrique Alegre

Understanding how the brain represents and processes information is crucial for advancing neuroscience and artificial intelligence. Representational similarity analysis (RSA) has been instrumental in characterizing neural representations,…

神经元与认知 · 定量生物学 2024-08-23 Baihan Lin

Representation learning on large-scale unstructured volumetric and surface meshes poses significant challenges in neuroimaging, especially when models must incorporate diverse vertex-level morphometric descriptors, such as cortical…

计算机视觉与模式识别 · 计算机科学 2026-04-08 Yujian Xiong , Mohammad Farazi , Yanxi Chen , Wenhui Zhu , Xuanzhao Dong , Natasha Lepore , Yi Su , Raza Mushtaq , Stephen Foldes , Andrew Yang , Yalin Wang

In the realm of machine learning, traditional model development and automated approaches like AutoML typically rely on layers of abstraction, such as tree-based or Cartesian genetic programming. Our study introduces "Guided Evolution" (GE),…

神经与进化计算 · 计算机科学 2024-07-18 Clint Morris , Michael Jurado , Jason Zutty

We create an artificial system of agents (attention-based neural networks) which selectively exchange messages with each-other in order to study the emergence of memetic evolution and how memetic evolutionary pressures interact with genetic…

人工智能 · 计算机科学 2021-04-09 Nicholas Guttenberg , Marek Rosa

Deep Learning (DL) in neuroimaging has become increasingly relevant for detecting neurological conditions and neurodegenerative disorders. One of the most predominant biomarkers in neuroimaging is represented by brain age, which has been…

图像与视频处理 · 电气工程与系统科学 2025-11-20 Carlo Alberto Barbano , Matteo Brunello , Benoit Dufumier , Marco Grangetto

Given an atlas of the brain and a number of injections to be performed in order to map out the connections between parts of the brain, we propose an algorithm to compute the coordinates of the injections. The algorithm is designed to sample…

定量方法 · 定量生物学 2011-04-15 Pascal Grange , Partha P. Mitra

Epigenetics is the study of how people's behavior and environments influence the way their genes are expressed, even though their DNA sequence is itself unchanged. By aggregating age-related epigenetic markers, epigenetic 'clocks' have…

综合经济学 · 经济学 2025-09-19 Giorgia Menta , Pietro Biroli , Divya Mehta , Conchita D'Ambrosio , Deborah Cobb-Clark

Brain age prediction serves as a powerful framework for assessing brain status and detecting deviations associated with neurodevelopmental and neurodegenerative disorders. However, most existing approaches emphasize whole-brain age…

神经元与认知 · 定量生物学 2026-02-10 Rongzhao He , Dalin Zhu , Ying Wang , Songhong Yue , Leilei Zhao , Yu Fu , Dan Wu , Bin Hu , Weihao Zheng

The last decades have seen significant advancements in non-invasive neuroimaging technologies that have been increasingly adopted to examine human brain development. However, these improvements have not necessarily been followed by more…

神经元与认知 · 定量生物学 2021-12-28 Mehrin Kiani , Javier Andreu-Perez , Hani Hagras , Silvia Rigato , Maria Laura Filippetti

Motivation: Gene expression during brain development or abnormal development is a biological process that is highly dynamic in spatio and temporal. Due to the lack of comprehensive integration of spatial and temporal dimensions of brain…

定量方法 · 定量生物学 2023-10-19 Shanjun Mao , Xiao Huang , Runjiu Chen , Chenyang Zhang , Yizhu Diao , Zongjin Li , Qingzhe Wang , Shan Tang , Shuixia Guo

The surface morphology of the developing mammalian brain is crucial for understanding brain function and dysfunction. Computational modeling offers valuable insights into the underlying mechanisms for early brain folding. Recent findings…

神经元与认知 · 定量生物学 2024-09-06 Jixin Hou , Zhengwang Wu , Xianyan Chen , Li Wang , Dajiang Zhu , Tianming Liu , Gang Li , Xianqiao Wang

The pursuit of artificial general intelligence necessitates robust methods for evaluating the cognitive capabilities of models beyond narrow task performance. Here, we introduce a psychometric framework to assess the cognitive profiles of…

人工智能 · 计算机科学 2026-05-11 Isaac Galatzer-Levy , Daniel McDuff , Xin Liu , Jed McGiffin