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Approximately 24 million pregnant women in Sub-Saharan Africa are at risk of suffering from pregnancy malaria complications. Mechanisms responsible for increased susceptibility to malaria in pregnant women are not fully understood. Baboons…

Pregnant women have increased susceptibility to malaria infection. In these women, malaria parasites are frequently found sequestered in the placental intervillous spaces, a condition referred to as placental malaria (PM). Placental malaria…

细胞行为 · 定量生物学 2012-04-18 Barasa Mustafa , Gicheru Muita MichaeL , Kagasi Ambogo Esther , Ozwara Suba Hastings

Malaria parasites are known to mediate the induction of inflammatory immune responses at the maternal-foetal interface during placental malaria (PM) leading to adverse consequences like pre-term deliveries and abortions. Immunological…

Malaria is a major contributor to health burdens throughout the regions where it is endemic. Historically, it was believed that there was limited morbidity and essentially no mortality associated with Plasmodium vivax; however, evidence…

种群与进化 · 定量生物学 2015-05-11 Andrew A. Lover

Malaria is a mosquito-borne disease with a devastating global impact. Plasmodium vivax is a major cause of human malaria beyond sub-Saharan Africa. Relapsing infections, driven by a reservoir of liver-stage parasites known as hypnozoites,…

种群与进化 · 定量生物学 2021-07-05 Somya Mehra , Eva Stadler , David Khoury , James M. McCaw , Jennifer A. Flegg

Plasmodium vivax is one of the most geographically widespread malaria parasites in the world due to its ability to remain dormant in the human liver as hypnozoites and subsequently reactivate after the initial infection (i.e. relapse…

Malaria is an infectious disease with an immense global health burden. Plasmodium vivax is the most geographically widespread species of malaria. Relapsing infections, caused by the activation of liver-stage parasites known as hypnozoites,…

种群与进化 · 定量生物学 2021-06-25 Somya Mehra , James M. McCaw , Mark B. Flegg , Peter G. Taylor , Jennifer A. Flegg

Malaria is one of the deadliest infectious diseases globally, causing hundreds of thousands of deaths each year. It disproportionately affects young children, with two-thirds of fatalities occurring in under-fives. Individuals acquire…

种群与进化 · 定量生物学 2023-06-07 Zhuolin Qu , Denis Patterson , Lauren Childs , Christina Edholm , Joan Ponce , Olivia Prosper , Lihong Zhao

A timely immunization can be effective against certain diseases and can save thousands of lives. However, for some diseases it has been difficult, so far, to develop an efficient vaccine. Malaria, a tropical disease caused by a parasite of…

基因组学 · 定量生物学 2016-11-08 Raul Isea , Rafael Mayo-Garcia , Silvia Restrepo

Malaria is a vector-borne disease that exacts a grave toll in the Global South. The epidemiology of Plasmodium vivax, the most geographically expansive agent of human malaria, is characterised by the accrual of a reservoir of dormant…

种群与进化 · 定量生物学 2022-08-23 Somya Mehra , Peter G. Taylor , James M. McCaw , Jennifer A. Flegg

Plasmodium vivax malaria is a mosquito-borne disease of significant public health importance. A defining feature of the within-host biology of P. vivax is the accrual of a hypnozoite reservoir, comprising a bank of quiescent parasites in…

种群与进化 · 定量生物学 2025-02-26 Somya Mehra , Peter G. Taylor

Malaria is mosquito-borne blood disease caused by parasites of the genus Plasmodium. Conventional diagnostic tool for malaria is the examination of stained blood cell of patient in microscope. The blood to be tested is placed in a slide and…

图像与视频处理 · 电气工程与系统科学 2018-03-30 Suman Kunwar

Malaria and other parasites, including virus often induce an increase in host lipids which the invaders use to their own advantage. We obtained encouraging results in our investigations on bird malaria with a new approach namely the use of…

生物大分子 · 定量生物学 2007-07-19 Ayesha Rahman , Dipankar Seth , Nitai Debnath , C. Ulrichs , I. Mewis , R. L. Brahmachary , A. Goswami

According to the World Malaria Report of 2022, 247 million cases of malaria and 619,000 related deaths were reported in 2021. This highlights the predominance of the disease, especially in the tropical and sub-tropical regions of Africa,…

图像与视频处理 · 电气工程与系统科学 2023-04-07 Sanya Sinha , Nilay Gupta

Plasmodium (P.) falciparum and P. vivax are the two most common causes of malaria. While the majority of deaths and severe morbidity are due to P. falciparum, P. vivax poses a greater challenge to eliminating malaria outside of Africa due…

Malaria, a mosquito-borne disease caused by a parasite, kills over 1 million people globally each year. People, if left untreated, may develop severe complications, leading to death. Effective and accurate diagnosis is important for the…

图像与视频处理 · 电气工程与系统科学 2020-09-02 Alexander Tao , Boran Han

The epidemiological behavior of Plasmodium vivax malaria occurs across spatial scales including within-host, population, and metapopulation levels. On the within-host scale, P. vivax sporozoites inoculated in a host may form latent…

种群与进化 · 定量生物学 2023-12-12 Shoshana Elgart , Mark B. Flegg , Somya Mehra , Jennifer A. Flegg

In this paper, a co-infection of malaria and visceral helminthiasis with immune stimulation and impairment is studied. We have assumed that an individual gets malaria infection during invasion by helminths larvae. In absence of immune…

种群与进化 · 定量生物学 2011-06-06 Betty Nannyonga , J. Y. T. Mugisha , L. S. Luboobi

Malaria is a parasitic disease, transmitted by mosquito vectors. Plasmodium vivax presents particular challenges for disease control, in light of an undetectable reservoir of latent parasites (hypnozoites) within the host liver.…

种群与进化 · 定量生物学 2023-06-27 Somya Mehra , James M. McCaw , Peter G. Taylor

Malaria remains a prevalent health concern in regions with tropical and subtropical climates. The cause of malaria is the Plasmodium parasite, which is transmitted through the bites of infected female Anopheles mosquitoes. Traditional…

计算机视觉与模式识别 · 计算机科学 2025-12-30 Md. Ismiel Hossen Abir , Awolad Hossain
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