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A framework for online robust adaptive radiation therapy (ART) is presented. This framework is designed to (i) handle interfractional geometric variations following a probability distribution different from the a priori hypothesis, (ii)…

医学物理 · 物理学 2020-09-09 Michelle Böck

In the treatment plan optimization for intensity modulated radiation therapy (IMRT), dose-deposition coefficient (DDC) matrix is often pre-computed to parameterize the dose contribution to each voxel in the volume of interest from each…

医学物理 · 物理学 2013-03-15 Zhen Tian , Masoud Zarepisheh , Xun Jia , Steve B. Jiang

Conventional planning objectives in optimization of intensity-modulated radiotherapy treatment (IMRT) plans are designed to minimize the violation of dose-volume histogram (DVH) thresholds using penalty functions. Although successful in…

医学物理 · 物理学 2023-07-19 Lovisa Engberg , Kjell Eriksson , Anders Forsgren , Björn Hårdemark

Objective: Radiation therapy treatment planning is a time-consuming process involving iterative adjustments of hyperparameters. To automate the treatment planning process, we propose a meta-optimization framework, called MetaPlanner (MP).…

医学物理 · 物理学 2022-02-22 Charles Huang , Yusuke Nomura , Yong Yang , Lei Xing

The field of portfolio selection is an active research topic, which combines elements and methodologies from various fields, such as optimization, decision analysis, risk management, data science, forecasting, etc. The modeling and…

投资组合管理 · 定量金融 2020-10-28 A. Georgantas

In robust optimization one seeks to make a decision under uncertainty, where the goal is to find the solution with the best worst-case performance. The set of possible realizations of the uncertain data is described by a so-called…

最优化与控制 · 数学 2022-01-25 Immanuel Bomze , Markus Gabl

A robust adaptive model predictive control (MPC) algorithm is presented for linear, time invariant systems with unknown dynamics and subject to bounded measurement noise. The system is characterized by an impulse response model, which is…

系统与控制 · 电气工程与系统科学 2019-11-21 Anilkumar Parsi , Andrea Iannelli , Mingzhou Yin , Mohammad Khosravi , Roy S. Smith

Bayesian optimization is a popular tool for data-efficient optimization of expensive objective functions. In real-life applications like engineering design, the designer often wants to take multiple objectives as well as input uncertainty…

人工智能 · 计算机科学 2022-02-28 J. Qing , I. Couckuyt , T. Dhaene

Geometric uncertainty can degrade treatment quality in radiation therapy. While margins and robust optimization mitigate these effects, they provide only implicit control over clinical goal fulfillment probability. We therefore develop a…

医学物理 · 物理学 2026-01-14 Albin Fredriksson , Erik Engwall , Jenneke de Jong , Johan Sundström

In neural combinatorial optimization (CO), reinforcement learning (RL) can turn a deep neural net into a fast, powerful heuristic solver of NP-hard problems. This approach has a great potential in practical applications because it allows…

机器学习 · 计算机科学 2021-07-14 Yeong-Dae Kwon , Jinho Choo , Byoungjip Kim , Iljoo Yoon , Youngjune Gwon , Seungjai Min

Automated experimentation has the potential to revolutionize scientific discovery, but its effectiveness depends on well-defined optimization targets, which are often uncertain or probabilistic in real-world settings. In this work, we…

机器学习 · 计算机科学 2025-04-10 Yu Liu , Sergei V. Kalinin

Recently, Masked Diffusion Models (MDMs) have shown promising potential across vision, language, and cross-modal generation. However, a notable discrepancy exists between their training and inference procedures. In particular, MDM inference…

机器学习 · 计算机科学 2025-12-30 Renping Zhou , Zanlin Ni , Tianyi Chen , Zeyu Liu , Yang Yue , Yulin Wang , Yuxuan Wang , Jingshu Liu , Gao Huang

In this study, we propose a novel multi-objective Bayesian optimization (MOBO) method to efficiently identify the Pareto front (PF) defined by risk measures for black-box functions under the presence of input uncertainty (IU). Existing BO…

机器学习 · 统计学 2023-11-27 Yu Inatsu , Shion Takeno , Hiroyuki Hanada , Kazuki Iwata , Ichiro Takeuchi

Reliability-based design optimization (RBDO) approaches aim to identify the best design of an engineering problem, whilst the probability of failure (PoF) remains below an acceptable value. Thus, the incorporation of the sharpest bounds on…

计算工程、金融与科学 · 计算机科学 2025-03-18 Niklas Miska , Daniel Balzani

Multiple-objective optimization (MOO) aims to simultaneously optimize multiple conflicting objectives and has found important applications in machine learning, such as minimizing classification loss and discrepancy in treating different…

机器学习 · 计算机科学 2022-09-16 Eric Enouen , Katja Mathesius , Sean Wang , Arielle Carr , Sihong Xie

A novel distributed algorithm is proposed for finite-time converging to a feasible consensus solution satisfying global optimality to a certain accuracy of the distributed robust convex optimization problem (DRCO) subject to bounded…

最优化与控制 · 数学 2023-09-06 Xunhao Wu , Jun Fu

Robust PCA has drawn significant attention in the last decade due to its success in numerous application domains, ranging from bio-informatics, statistics, and machine learning to image and video processing in computer vision. Robust PCA…

最优化与控制 · 数学 2018-06-12 Shiqian Ma , Necdet Serhat Aybat

The problem of rate control in multi-user multiple-input multiple-output (MIMO) interference systems is formulated as a multicriteria optimization (MCO) problem. The Pareto rate region of the MCO problem is characterized. It is shown that…

计算机科学与博弈论 · 计算机科学 2013-02-20 Zengmao Chen , Sergiy A. Vorobyov , Cheng-Xiang Wang , John Thompson

This chapter assesses the sensitivity of multi-criteria decision-making (MCDM) methods to modifications within the decision or objective matrix (DOM) in the context of chemical engineering optimization applications. Employing eight common…

化学物理 · 物理学 2025-07-11 Seyed Reza Nabavi , Zhiyuan Wang , Gade Pandu Rangaiah

We consider linear programs involving uncertain parameters and propose a new tractable robust counterpart which contains and generalizes several other models including the existing Affinely Adjustable Robust Counterpart and the Fully…

最优化与控制 · 数学 2016-04-12 Walid Ben-Ameur , Adam Ouorou , Guanglei Wang , Mateusz Żotkiewicz