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相关论文: Transport Characteristics of Molecular Motors

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The mathematical formulation of the model for molecular movement of single motor proteins driven by cyclic biochemical reactions in an aqueous environment leads to a drifted Brownian motion characterized by coupled diffusion equations. In…

统计力学 · 物理学 2007-05-23 Hong Qian

Transport phenomena in spatially periodic systems far from thermal equilibrium are considered. The main emphasize is put on directed transport in so-called Brownian motors (ratchets), i.e. a dissipative dynamics in the presence of thermal…

统计力学 · 物理学 2009-10-31 Peter Reimann

In recent literature there has been a lot of interest in the phenomena of noise induced transport in the absence of an average bias occurring in spatially periodic systems far from equilibrium. One of the main motivations in this area is to…

生物物理 · 物理学 2007-05-23 Raishma Krishnan , A. M. Jayannavar

Dynamic properties of molecular motors that fuel their motion by actively interacting with underlying molecular tracks are studied theoretically via discrete-state stochastic ``burnt-bridge'' models. The transport of the particles is viewed…

软凝聚态物质 · 物理学 2009-11-13 Maxim N. Artyomov , Alexander Yu. Morozov , Ekaterina Pronina , Anatoly B. Kolomeisky

We analyze the performance of a Brownian ratchet in the presence of geometrical constraints. A two-state model that describes the kinetics of molecular motors is used to characterize the energetic cost when the motor proceeds under…

生物物理 · 物理学 2015-06-23 Paolo Malgaretti , Ignacio Pagonabarraga , J. Miguel Rubi

A molecular motor is made of either a single macromolecule or a macromolecular complex. Just like their macroscopic counterparts, molecular motors "transduce" input energy into mechanical work. All the nano-motors considered here operate…

生物物理 · 物理学 2013-07-18 Debashish Chowdhury

We consider in this paper a solvable model for the motion of molecular motors. Based on the averaging principle, we reduce the problem to a diffusion process on a graph. We then calculate the effective speed of transportation of these…

概率论 · 数学 2013-06-11 Mark Freidlin , Wenqing Hu

Molecules with complex internal structure in time-dependent periodic potentials are studied by using short Rubinstein-Duke model polymers as an example. We extend our earlier work on transport in stochastically varying potentials to cover…

统计力学 · 物理学 2015-05-18 Janne Kauttonen , Juha Merikoski

The muscle contraction, operation of ATP synthase, maintaining the shape of a cell are believed to be secured by motor proteins, which can be modelled using the Brownian ratchet mechanism. We consider the randomly flashing ratchet model of…

经典分析与常微分方程 · 数学 2013-05-09 Dmitry Vorotnikov

Processive molecular motors which drive the traffic of organelles in cells move in a directed way along cytoskeletal filaments. On large time scales, they perform motor walks, i.e., peculiar random walks which arise from the repeated…

统计力学 · 物理学 2007-05-23 Stefan Klumpp , Theo M. Nieuwenhuizen , Reinhard Lipowsky

We examine the dependence of the physical quantities of the rotatory molecular motor, such as the rotation velocity and the proton translocation rate, on the chemical reaction rate using the model based only on diffusion process. A peculiar…

生物物理 · 物理学 2009-11-10 Hiroshi Miki , Masatoshi Sato , Mahito Kohmoto

Motor-driven intracellular transport of organelles, vesicles, and other molecular cargo is a highly collective process. An individual cargo is often pulled by a team of transport motors, with numbers ranging from only a few to several…

统计力学 · 物理学 2022-01-06 Matthew P. Leighton , David A. Sivak

Biological transport is supported by collective dynamics of enzymatic molecules that are called motor proteins or molecular motors. Experiments suggest that motor proteins interact locally via short-range potentials. We investigate the…

统计力学 · 物理学 2015-06-18 Hamid Teimouri , Anatoly B. Kolomeisky , Kareem Mehrabiani

We study the flashing ratchet model of a Brownian motor, which consists in cyclical switching between the Fokker-Planck equation with an asymmetric ratchet-like potential and the pure diffusion equation. We show that the motor really…

偏微分方程分析 · 数学 2012-01-13 Dmitry Vorotnikov

A light-driven molecular motor system is investigated using a multi-state Brownian ratchet model described by a single effective coordinate with multiple electronic states in a dissipative environment. The rotational motion of the motor…

化学物理 · 物理学 2019-03-22 Tatsushi Ikeda , Arend G. Dijkstra , Yoshitaka Tanimura

We propose a stochastic process wherein molecular transport is mediated by asymmetric nucleation of domains on a one-dimensional substrate. Track-driven mechanisms of molecular transport arise in biophysical applications such as Holliday…

统计力学 · 物理学 2009-11-13 Amit Lakhanpal , Tom Chou

The directed transport of an overdamped Brownian motor moving in a spatially periodic potential that lacks reflection symmetry (i.e. a ratchet potential) is studied when driven by thermal and dichotomic nonequilibrium noise in the presence…

软凝聚态物质 · 物理学 2008-08-05 Lukasz Machura , Jerzy Luczka , Peter Talkner , Peter Hänggi

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

生物物理 · 物理学 2017-03-30 Isabella R. Graf , Erwin Frey

The stochastic driving force exerted by a single molecular motor (e.g., a kinesin, or myosin) moving on a periodic molecular track (microtubule, actin filament, etc.) is discussed from a general viewpoint open to experimental test. An…

统计力学 · 物理学 2009-10-31 Michael E. Fisher , Anatoly B. Kolomeisky

Routinely navigating through an ever-changing and unsteady environment, and utilizing chemical energy, molecular motors transport the cell's crucial components, such as neurotransmitters and organelles. They generate force and pull cargo,…

生物物理 · 物理学 2012-09-28 Bartosz Lisowski , Michał Żabicki
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