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相关论文: Length-dependent translocation of polymers through…

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We consider the dynamics of a translocation process of a flexible linear polymer through a nanopore into an environment of active rods in the {\it trans} side. Using Langevin dynamics simulations we find that the rods facilitate…

软凝聚态物质 · 物理学 2022-11-15 Hamidreza Khalilian , Jalal Sarabadani , Tapio Ala-Nissila

We perform two-dimensional Langevin dynamics simulations of electric-field driven polymer translocation through an attractive nanopore. We investigate the effect of the location of the attractive region using different pore patterns. This…

软凝聚态物质 · 物理学 2015-06-15 F Piguet , D P Foster

We report a numerical study of the diffusiophoresis of short polymers using non-equilibrium molecular dynamics simulations. More precisely, we consider polymer chains in a fluid containing a solute which has a concentration gradient, and…

软凝聚态物质 · 物理学 2020-05-20 Simón Ramírez-Hinestrosa , Hiroaki Yoshida , Lydéric Bocquet , Daan Frenkel

The diffusion of molecules (penetrants) of variable size, shape, and chemistry through dense crosslinked polymer networks is a fundamental scientific problem that is broadly relevant in materials, polymer, physical and biological chemistry.…

We present results from our simulations of biopolymer translocation in a solvent which explain the main experimental findings. The forced translocation can be described by simple force balance arguments for the relevant range of pore…

生物物理 · 物理学 2009-05-08 V. V. Lehtola , R. P. Linna , K. Kaski

In recent years polymer translocation, i.e., transport of polymeric molecules through nanometer-sized pores and channels embedded in membranes, has witnessed strong advances. It is now possible to observe single-molecule polymer dynamics…

软凝聚态物质 · 物理学 2013-09-13 Debabrata Panja , Gerard T. Barkema , Anatoly B. Kolomeisky

The translocation of a macromolecule through a nanometer-sized pore is an interesting process with important applications in the development of biosensors for single--molecule analysis and in drug delivery and gene therapy. We have carried…

统计力学 · 物理学 2009-09-29 Yves Lansac , Prabal K. Maiti , Matthew A. Glaser

We consider the translocation of a one-dimensional polymer through a pore channel helped by a motor driven by a dichotomous noise with time exponential correlation. We are interested in the study of the translocation time, mean velocity and…

软凝聚态物质 · 物理学 2012-03-01 Alessandro Fiasconaro , Juan José Mazo , Fernando Falo

We employ a multiscale approach to model the translocation of biopolymers through nanometer size pores. Our computational scheme combines microscopic Langevin molecular dynamics (MD) with a mesoscopic lattice Boltzmann (LB) method for the…

生物物理 · 物理学 2011-11-10 Maria Fyta , Simone Melchionna , Efthimios Kaxiras , Sauro Succi

In biology, there are several processes in which unfolded protein chains are transported along narrow-tube channels. Normally, without such a severe configurational constraint, unfolded polypeptides would not bind to each other. However,…

软凝聚态物质 · 物理学 2019-09-19 Gillian M. Fraser , Eugene M. Terentjev

We investigate the dynamics of polymer translocation through nanopores under external driving by 3D Langevin Dynamics simulations, focusing on the scaling of the average translocation time $\tau$ versus the length of the polymer, $\tau\sim…

软凝聚态物质 · 物理学 2010-01-04 Kaifu Luo , Tapio Ala-Nissila , See-Chen Ying , Ralf Metzler

We investigate the translocation dynamics of a folded linear polymer which is pulled through a nanopore by an external force. To this end, we generalize the iso-flux tension propagation (IFTP) theory for end-pulled polymer translocation to…

软凝聚态物质 · 物理学 2019-12-18 Bappa Ghosh , Jalal Sarabadani , Srabanti Chaudhury , Tapio Ala-Nissila

Polymer translocation through a nano-pore in a thin membrane is studied using a coarse-grained bead-spring model and Langevin dynamics simulation with a particular emphasis to explore out of equilibrium characteristics of the translocating…

软凝聚态物质 · 物理学 2015-05-14 Aniket Bhattacharya , Kurt Binder

Chaperone-assisted translocation through a nanopore embedded in membrane holds a prominent role in the transport of biopolymers. Inspired by classical Brownian ratchet, we develop a theoretical framework characterizing such translocation…

生物物理 · 物理学 2020-02-17 Xining Xu , Yunxin Zhang

We investigate a model of chaperone-assisted polymer translocation through a nanopore in a membrane. Translocation is driven by irreversible random sequential absorption of chaperone proteins that bind to the polymer on one side of the…

统计力学 · 物理学 2015-05-19 Paul Krapivsky , Kirone Mallick

We investigate the translocation of stiff polymers in the presence of binding particles through a nanopore by two-dimensional Langevin dynamics simulations. We find that the mean translocation time shows a minimum as a function of the…

软凝聚态物质 · 物理学 2015-06-12 Wancheng Yu , Yiding Ma , Kaifu Luo

Theoretical results for the extension of a polymer confined to a channel are usually derived in the limit of infinite contour length. But experimental studies and simulations of DNA molecules confined to nanochannels are not necessarily in…

软凝聚态物质 · 物理学 2015-12-23 T. St Clere Smithe , V. Iarko , A. Muralidhar , E. Werner , K. D. Dorfman , B. Mehlig

Polymer chains undergoing a continuous adsorption-desorption transition are studied through extensive computer simulations. A three-dimensional self-avoiding walk lattice model of a polymer chain grafted onto a surface has been treated for…

统计力学 · 物理学 2018-05-30 P. H. L. Martins , J. A. Plascak , M. Bachmann

We investigate the chain conformation of ring polymers confined to a cylindrical nanochannel using both theoretical analysis and three dimensional Langevin dynamics simulations. We predict that the longitudinal size of a ring polymer scales…

软凝聚态物质 · 物理学 2012-12-06 Junfang Sheng , Kaifu Luo

Nano-scale confinement of polymer in cone-shaped geometries occurs in many experimental situations. A flexible polymer confined in a cone-shaped nano-channel is studied theoretically and using molecular dynamics simulations. Distribution of…

软凝聚态物质 · 物理学 2016-02-24 Narges Nikoofard , Hossein Fazli