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We study the problem of subgroup discovery for survival analysis, where the goal is to find an interpretable subset of the data on which a Cox model is highly accurate. Our work is the first to study this particular subgroup problem, for…

机器学习 · 计算机科学 2026-01-06 Zachary Izzo , Iain Melvin

For sparse high-dimensional regression problems, Cox and Battey [1, 9] emphasised the need for confidence sets of models: an enumeration of those small sets of variables that fit the data equivalently well in a suitable statistical sense.…

统计方法学 · 统计学 2025-06-10 R. M. Lewis , H. S. Battey

Covariance regression analysis is an approach to linking the covariance of responses to a set of explanatory variables $X$, where $X$ can be a vector, matrix, or tensor. Most of the literature on this topic focuses on the "Fixed-$X$"…

统计理论 · 数学 2025-01-08 Tao Zou , Wei Lan , Runze Li , Chih-Ling Tsai

We extend the work of Hahn and Carvalho (2015) and develop a doubly-regularized sparse regression estimator by synthesizing Bayesian regularization with penalized least squares within a decision-theoretic framework. In contrast to existing…

统计方法学 · 统计学 2025-02-04 Aihua Li , Surya T. Tokdar , Jason Xu

Practical optimization problems may contain different kinds of difficulties that are often not tractable if one relies on a particular optimization method. Different optimization approaches offer different strengths that are good at…

神经与进化计算 · 计算机科学 2024-07-08 Ankur Sinha , Dhaval Pujara , Hemant Kumar Singh

Survival Analysis (SA) constitutes the default method for time-to-event modeling due to its ability to estimate event probabilities of sparsely occurring events over time. In this work, we show how to improve the training and inference of…

机器学习 · 计算机科学 2023-12-12 Chris Solomou

Cox proportional hazards model is one of the most popular models in biomedical data analysis. There have been continuing efforts to improve the flexibility of such models for complex signal detection, for example, via additive functions.…

统计方法学 · 统计学 2022-05-25 Boyi Guo , Nengjun Yi

The purpose of this article is to provide an adaptive estimator of the baseline function in the Cox model with high-dimensional covariates. We consider a two-step procedure : first, we estimate the regression parameter of the Cox model via…

统计理论 · 数学 2015-03-04 Agathe Guilloux , Sarah Lemler , Marie-Luce Taupin

Analysis of survival data with biased samples caused by left-truncation or length-biased sampling has received extensive interest. Many inference methods have been developed for various survival models. These methods, however, break down…

统计理论 · 数学 2018-12-31 Li-Pang Chen

In this paper we utilize a survival analysis methodology incorporating Bayesian additive regression trees to account for nonlinear and additive covariate effects. We compare the performance of Bayesian additive regression trees, Cox…

应用统计 · 统计学 2019-11-05 Satabdi Saha , Duchwan Ryu , Nader Ebrahimi

Background: The development of classification methods for personalized medicine is highly dependent on the identification of predictive genetic markers. In survival analysis it is often necessary to discriminate between influential and…

统计方法学 · 统计学 2018-02-27 Thomas Welchowski , Verena Zuber , Matthias Schmid

Covariate adjustment aims to improve the statistical efficiency of randomized trials by incorporating information from baseline covariates. Popular methods for covariate adjustment include analysis of covariance for continuous endpoints and…

统计方法学 · 统计学 2025-05-09 Zhiwei Zhang , Ya Wang , Dong Xi

We extend the decomposition approach for learning Bayesian networks (BNs) proposed by (Xie et. al.) to learning multivariate regression chain graphs (MVR CGs), which include BNs as a special case. The same advantages of this decomposition…

人工智能 · 计算机科学 2020-02-26 Mohammad Ali Javidian , Marco Valtorta

A central problem in data science is to use potentially noisy samples of an unknown function to predict values for unseen inputs. In classical statistics, predictive error is understood as a trade-off between the bias and the variance that…

统计理论 · 数学 2025-06-04 Mark K. Transtrum , Gus L. W. Hart , Tyler J. Jarvis , Jared P. Whitehead

We tackle the problem of computing counterfactual explanations -- minimal changes to the features that flip an undesirable model prediction. We propose a solution to this question for linear Support Vector Machine (SVMs) models. Moreover,…

机器学习 · 计算机科学 2022-12-16 Sebastian Salazar , Samuel Denton , Ansaf Salleb-Aouissi

In survival analysis, the lifetime under study is not always observed. In certain applications, for some individuals, the value of the lifetime is only known to be smaller or larger than some random duration. This framework represent an…

统计理论 · 数学 2020-02-25 Laurent Bordes , Maria Carmen Pardo , Christian Paroissin , Valentin Patilea

In observational studies with survival or time-to-event outcomes, a propensity score weighted marginal Cox proportional hazard model with the treatment variable as the only predictor is commonly used to estimate the causal marginal hazard…

统计方法学 · 统计学 2026-02-02 Zixian Zhao , Chengxin Yang , Fan Li

Discrimination and calibration represent two important properties of survival analysis, with the former assessing the model's ability to accurately rank subjects and the latter evaluating the alignment of predicted outcomes with actual…

机器学习 · 计算机科学 2024-06-04 Shi-ang Qi , Yakun Yu , Russell Greiner

Motivated by graphical models, we consider the "Sparse Plus Low-rank" decomposition of a positive definite concentration matrix -- the inverse of the covariance matrix. This is a classical problem for which a rich theory and numerical…

最优化与控制 · 数学 2019-01-31 Valentina Ciccone , Augusto Ferrante , Mattia Zorzi

We introduce a semi-parametric Bayesian model for survival analysis. The model is centred on a parametric baseline hazard, and uses a Gaussian process to model variations away from it nonparametrically, as well as dependence on covariates.…

机器学习 · 统计学 2016-11-04 Tamara Fernández , Nicolás Rivera , Yee Whye Teh