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X-ray fluorescence computed tomography based on sheet-beam can save a huge amount of time to obtain a whole set of projections using synchrotron. However, it is clearly unpractical for most biomedical research laboratories. In this paper,…

医学物理 · 物理学 2017-03-07 Shanghai Jiang , Peng He , Luzhen Deng , Mianyi Chen , Biao Wei

Purpose: To verify dose delivery and quality assurance of volumetric modulated arc therapy (VMAT) for head and neck cancer. Method: The Imaging and Radiation Oncology Core Houston (IROC-H) head and neck phantom with thermo- luminescent…

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

医学物理 · 物理学 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

SPECT imaging is one of the common modalities used to examine kidney disease. The radiopharmaceuticals such as 99mTc-MAG3, 99mTc-DTPA, and 99mTc-DMSA are commonly employed for pediatric patients. It is generally accepted that children…

Objective: To propose a CBCT dose optimization method using readily available measurement equipment in radiation oncology departments. Approach: A 0.6cc air kerma (Kair) calibrated Farmer chamber measured Kair at isocenter for five default…

医学物理 · 物理学 2025-02-04 S. Gros , J. Bian , J. Jackson , M. Delafuente , H. Kang , W. Small , M. Mahesh

In this study, the absorbed dose calculation for the cerebral region is refined using the Geant4 software, along with the ROOT and GATE programs. This approach provides a detailed statistical analysis of positron trajectories within a water…

医学物理 · 物理学 2025-05-06 Walter Sabalza-Castillejo , Miguel Martin-Landrove

Cone-beam computed tomography (CBCT) is a valuable imaging method in dental diagnostics that provides information not available in traditional 2D imaging. However, interpretation of CBCT images is a time-consuming process that requires a…

计算机视觉与模式识别 · 计算机科学 2018-10-25 Adel Zakirov , Matvey Ezhov , Maxim Gusarev , Vladimir Alexandrovsky , Evgeny Shumilov

Purpose: Scatter artifacts drastically degrade the image quality of cone-beam computed tomography (CBCT) scans. Although deep learning-based methods show promise in estimating scatter from CBCT measurements, their deployment in mobile CBCT…

信号处理 · 电气工程与系统科学 2025-09-12 Harshit Agrawal , Ari Hietanen , Simo Särkkä

Cone-beam computed tomography (CBCT) systems, with their flexibility, present a promising avenue for direct point-of-care medical imaging, particularly in critical scenarios such as acute stroke assessment. However, the integration of CBCT…

This paper provides a fast and patient-specific scatter artifact correction method for cone-beam computed tomography (CBCT) used in image-guided interventional procedures. Due to increased irradiated volume of interest in CBCT imaging,…

医学物理 · 物理学 2015-01-20 Wei Zhao , Stephen Brunner , Kai Niu , Sebastian Schafer , Kevin Royalty , Guang-Hong Chen

To enable magnetic resonance (MR)-only radiotherapy and facilitate modelling of radiation attenuation in humans, synthetic-CT (sCT) images need to be generated. Considering the application of MR-guided radiotherapy and online adaptive…

This study proposes Scout-Dose-TCM for direct, prospective estimation of organ-level doses under tube current modulation (TCM) and compares its performance to two established methods. We analyzed contrast-enhanced chest-abdomen-pelvis CT…

Objective: Research on eye lens dosimetry for radiation workers has increased after the 2012 ICRP118 update on eye lens dose limits. However, corneal dosimetry remains underexplored due to historical focus and measurement challenges. This…

医学物理 · 物理学 2025-09-26 Zahra Akbari Khanaposhtani , Hossein Rajabi

Purpose: To obtain individualized internal doses with a Monte Carlo method in patients undergoing diagnostic FCH-PET studies and to compare such doses with the MIRD method calculations. Methods: A patient cohort of 17 males were imaged…

Space radiation remains one of the primary hazards to spaceflight crews. The unique nature of the intravehicular radiation spectrum makes prediction of biological outcomes difficult, with computational simulation-based efforts stymied by…

医学物理 · 物理学 2023-08-24 Chesal MA , Blue RS , Aunon-Chancellor SA , Chancellor JC

Computed Tomography (CT) imaging, while essential for diagnostics, exposes patients to ionizing radiation. To accurately quantify radiation dosage, this study introduces MIDSX, a specialized open-source Monte Carlo (MC) photon transport…

医学物理 · 物理学 2023-11-29 John Meneghini

Fast dose calculation is critical for online and real time adaptive therapy workflows. While modern physics-based dose algorithms must compromise accuracy to achieve low computation times, deep learning models can potentially perform dose…

医学物理 · 物理学 2023-07-19 Oscar Pastor-Serrano , Peng Dong , Charles Huang , Lei Xing , Zoltán Perkó

In radiation therapy (RT), the reliance on pre-treatment computed tomography (CT) images encounter challenges due to anatomical changes, necessitating adaptive planning. Daily cone-beam CT (CBCT) imaging, pivotal for therapy adjustment,…

计算机视觉与模式识别 · 计算机科学 2024-09-20 Joonil Hwang , Sangjoon Park , NaHyeon Park , Seungryong Cho , Jin Sung Kim

Significance: Monte Carlo (MC) methods are the gold-standard for modeling light-tissue interactions due to their accuracy. Mesh-based MC (MMC) offers enhanced precision for complex tissue structures using tetrahedral mesh models. Despite…

分布式、并行与集群计算 · 计算机科学 2025-12-01 Shijie Yan , Douglas Dwyer , David R. Kaeli , Qianqian Fang

BACKGROUND: Targeted Radionuclide Therapy (TRT) is a fast-growing field garnering much interest, however, dosimetry calculation techniques remain relatively simple. PURPOSE: To introduce egs_mird, a new Monte Carlo application built in…

医学物理 · 物理学 2022-04-06 Martin P. Martinov , Chidera Opera , Rowan M. Thomson , Ting-Yim Lee