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We have previously described RapidBrachyMCTPS, a brachytherapy treatment planning toolkit consisting of a graphical user interface (GUI) and a Geant4-based Monte Carlo (MC) dose calculation engine. This work describes the tools that have…

医学物理 · 物理学 2020-07-07 Harry Glickman , Majd Antaki , Christopher Deufel , Shirin A. Enger

The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…

仪器与探测器 · 物理学 2016-10-12 J. J Gomez-Cadenas , J. M. Benlloch-Rodríguez , P. Ferrario , F. Monrabal , J. Rodríguez , J. F. Toledo

Proton beam therapy has been developed to irradiate the tumor with higher precision and dose conformity compared to conventional X-ray irradiation. The dose conformity of this treatment modality may be further improved if narrower proton…

In image-guided radiotherapy (IGRT), four-dimensional cone-beam computed tomography (4D-CBCT) is critical for assessing tumor motion during a patients breathing cycle prior to beam delivery. However, generating 4D-CBCT images with…

医学物理 · 物理学 2025-01-09 Yabo Fu , Hao Zhang , Weixing Cai , Huiqiao Xie , Licheng Kuo , Laura Cervino , Jean Moran , Xiang Li , Tianfang Li

A low-complexity orthogonal multiplierless approximation for the 16-point discrete cosine transform (DCT) was introduced. The proposed method was designed to possess a very low computational cost. A fast algorithm based on matrix…

We accelerated an ab-initio molecular QMC calculation by using GPGPU. Only the bottle-neck part of the calculation is replaced by CUDA subroutine and performed on GPU. The performance on a (single core CPU + GPU) is compared with that on a…

计算物理 · 物理学 2012-04-06 Yutaka Uejima , Tomoharu Terashima , Ryo Maezono

CT perfusion imaging (CTP) plays an important role in decision making for the treatment of acute ischemic stroke with large vessel occlusion. Since the CT perfusion scan time is approximately one minute, the patient is exposed to a…

医学物理 · 物理学 2021-11-04 Vojtěch Kulvait , Philip Hoelter , Arnd Doerfler , Georg Rose

The specific absorbed fractions (SAF) for self- and cross-irradiation are effective tools for the internal dose estimation of inhalation and ingestion intakes of radionuclides. A set of SAFs of photon and electron were calculated using the…

医学物理 · 物理学 2014-10-31 Wen Wang , Meng-yun Cheng , Peng-cheng Long , Li-qin Hu

This research considers potential dose increase in target due to cisplatin (Pt) concentration and radiation type. Cisplatin concentrations from 0.003 to 120 mM were used. Monte-Carlo simulation of Linear accelerator (Elekta Synergy) and…

医学物理 · 物理学 2020-08-26 A. A. Baulin

Computer simulation plays a central role in modern day materials science. The utility of a given computational approach depends largely on the balance it provides between accuracy and computational cost. Molecular crystals are a class of…

Computed tomography (CT) is a beneficial imaging tool for diagnostic purposes. CT scans provide detailed information concerning the internal anatomic structures of a patient, but present higher radiation dose and costs compared to X-ray…

图像与视频处理 · 电气工程与系统科学 2024-03-05 Benjamin Paulson , Joshua Goldshteyn , Sydney Balboni , John Cisler , Andrew Crisler , Natalia Bukowski , Julia Kalish , Theodore Colwell

Delineating and planning with respect to regions suspected to contain microscopic tumor cells is an inherently uncertain task in radiotherapy. The recently proposed \textit{clinical target distribution} (CTD) is an alternative to the…

医学物理 · 物理学 2023-04-26 Ivar Bengtsson , Anders Forsgren , Albin Fredriksson

Treatment planning systems at proton-therapy centres generally use X-ray computed tomography (CT) as primary imaging technique to infer the proton treatment doses to tumour and healthy tissues. However, proton stopping powers in the body,…

The distribution of absorbed dose in radionuclide therapy with Lu$^{177}$ can be approximated by convolving an image of the time-integrated activity distribution with a dose voxel kernel representing different tissue types. This fast but…

机器学习 · 统计学 2026-03-25 Luciano Melodia

Obtaining accurate and reliable images from low-dose computed tomography (CT) is challenging. Regression convolutional neural network (CNN) models that are learned from training data are increasingly gaining attention in low-dose CT…

图像与视频处理 · 电气工程与系统科学 2019-08-06 Il Yong Chun , Xuehang Zheng , Yong Long , Jeffrey A. Fessler

Purpose: To apply a convolutional neural network (CNN) to develop a system that segments intensity calibration phantom regions in computed tomography (CT) images, and to test the system in a large cohort to evaluate its robustness. Methods:…

计算机视觉与模式识别 · 计算机科学 2020-12-22 Keisuke Uemura , Yoshito Otake , Masaki Takao , Mazen Soufi , Akihiro Kawasaki , Nobuhiko Sugano , Yoshinobu Sato

The Fast Dose Calculator (FDC), a track repeating algorithm Monte Carlo method was initially developed for proton therapy. The validation for proton therapy has been demonstrated in a previous work. This method can be expanded to ion…

医学物理 · 物理学 2018-09-18 Qianxia Wang , Antony Adair , Yu Deng , Hongliang Chen , M Moyers , James Lin , Pablo Yepes

Purpose: The physical properties of yttrium-90 (90Y) allow for imaging with positron emission tomography/computed tomography (PET/CT). The increased sensitivity of long axial field-of-view (LAFOV) PET/CT scanners possibly allows to overcome…

Magnetohydrodynamic (MHD) simulations based on the ideal MHD equations have become a powerful tool for modeling phenomena in a wide range of applications including laboratory, astrophysical, and space plasmas. In general, high-resolution…

计算物理 · 物理学 2010-11-23 Hon-Cheng Wong , Un-Hong Wong , Xueshang Feng , Zesheng Tang

Computed tomography (CT) to cone-beam computed tomography (CBCT) deformable image registration (DIR) is a crucial step in adaptive radiation therapy. Current intensity-based registration algorithms, such as demons, may fail in the context…

医学物理 · 物理学 2017-08-23 Xin Zhen , Xuejun Gu , Hao Yan , Linghong Zhou , Xun Jia , Steve B. Jiang
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