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We introduce a general class of branching Markov processes for the modelling of a parasite infection in a cell population. Each cell contains a quantity of parasites which evolves as a diffusion with positive jumps. The drift, diffusive…

概率论 · 数学 2023-08-31 Aline Marguet , Charline Smadi

We introduce a general class of branching Markov processes for the modelling of a parasite infection in a cell population. Each cell contains a quantity of parasites which evolves as a diffusion with positive jumps. The growth rate,…

概率论 · 数学 2020-11-02 Aline Marguet , Charline Smadi

To investigate interactions between parasite species in a host, a population of field voles was studied longitudinally, with presence or absence of six different parasites measured repeatedly. Although trapping sessions were regular, a…

应用统计 · 统计学 2013-01-29 Chris Sherlock , Tatiana Xifara , Sandra Telfer , Mike Begon

The emergence or adaptation of pathogens may lead to epidemics, highlighting the need for a thorough understanding of pathogen evolution. The tradeoff hypothesis suggests that virulence evolves to reach an optimal transmission intensity…

种群与进化 · 定量生物学 2024-12-09 Daniel A. M. Villela

We are interested in modeling some two-level population dynamics, resulting from the interplay of ecological interactions and phenotypic variation of individuals (or hosts) and the evolution of cells (or parasites) of two types living in…

概率论 · 数学 2011-01-21 Sylvie Méléard , Sylvie Roelly

A stochastic model for the growth of a virus in a cell population is introduced. The virus has two ways of spreading: either by allowing its host cell to live on and duplicate, or else by multiplying in large numbers within the host cell…

细胞行为 · 定量生物学 2012-10-30 Jakob E. Björnberg , Tom Britton , Erik I. Broman , Eviatar Natan

We present a model for host-parasite dynamics which incorporates both vertical and horizontal transmission as well as spatial structure. Our model consists of stacked contact processes (CP), where the dynamics of the host is a simple CP on…

生物物理 · 物理学 2015-05-26 Steven J. Court , Richard A. Blythe , Rosalind J. Allen

A host-parasite model is considered for a population of cells that can be of two types, A or B, and exhibits unilateral reproduction: while a B-cell always splits into two cells of the same type, the two daughter cells of an A-cell can be…

概率论 · 数学 2013-02-06 Gerold Alsmeyer , Sören Gröttrup

Inspired by DNA data of the human cytomegalovirus we propose a model of a two-type parasite population distributed over its hosts. The parasite is capable to persist in its host till the host dies, and to reinfect other hosts. To maintain…

概率论 · 数学 2019-01-15 Cornelia Pokalyuk , Anton Wakolbinger

Motivated by the study of a parasite infection in a cell line, we introduce a general class of Markov processes for the modelling of population dynamics. The population process evolves as a diffusion with positive jumps whose rate is a…

概率论 · 数学 2021-06-01 Aline Marguet , Charline Smadi

We analyse a model that describes the propagation of many pathogens within and between many species. A branching process approximation is used to compute the probability of disease outbreaks. Special cases of aquatic environments with two…

种群与进化 · 定量生物学 2026-05-21 Clotilde Djuikem , Julien Arino

We consider a discrete-time host-parasite model for a population of cells which are colonized by proliferating parasites. The cell population grows like an ordinary Galton-Watson process, but in reflection of real biological settings the…

概率论 · 数学 2015-05-18 Gerold Alsmeyer , Sören Gröttrup

Interactions among multiple infectious agents are increasingly recognized as a fundamental issue in the understanding of key questions in public health, regarding pathogen emergence, maintenance, and evolution. The full description of…

种群与进化 · 定量生物学 2013-08-21 Chiara Poletto , Sandro Meloni , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

种群与进化 · 定量生物学 2023-12-20 Cameron A. Smith , Ben Ashby

Spatial patterning can be crucially important for understanding the behavior of interacting populations. Here we investigate a simple model of parasite and host populations in which parasites are random walkers that must come into contact…

种群与进化 · 定量生物学 2015-09-07 J. J. Dong , B. Skinner , N. Breecher , B. Schmittmann , R. K. P. Zia

Different pathogens spreading in the same host population often generate complex co-circulation dynamics because of the many possible interactions between the pathogens and the host immune system, the host life cycle, and the space…

种群与进化 · 定量生物学 2014-12-18 Chiara Poletto , Sandro Meloni , Ashleigh Van Metre , Vittoria Colizza , Yamir Moreno , Alessandro Vespignani

Density dependent Markov population processes with countably many types can often be well approximated over finite time intervals by the solution of the differential equations that describe their average drift, provided that the total…

概率论 · 数学 2014-06-05 A. D. Barbour , Malwina Luczak

Rapidly mutating pathogens may be able to persist in the population and reach an endemic equilibrium by escaping hosts' acquired immunity. For such diseases, multiple biological, environmental and population-level mechanisms determine the…

We consider a branching model for a population of dividing cells infected by parasites. Each cell receives parasites by inheritance from its mother cell and independent contamination from outside the population. Parasites multiply randomly…

概率论 · 数学 2009-08-05 Vincent Bansaye

This paper presents a stochastic model motivated by the study of a virus-like evolving population with different mutation rates. This is a continuous time birth-death model: the birth processes are mutually-exciting Hawkes processes and the…

概率论 · 数学 2026-03-10 Rahul Roy , Dharmaraja Selvamuthu , Paola Tardelli
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