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Sorted L-One Penalized Estimation (SLOPE) has shown the nice theoretical property as well as empirical behavior recently on the false discovery rate (FDR) control of high-dimensional feature selection by adaptively imposing the…

统计理论 · 数学 2023-02-22 Jingxuan Liang , Hong Chen , Xuelin Zhang , Weifu Li , Xin Tang

The traditional approaches to false discovery rate (FDR) control in multiple hypothesis testing are usually based on the null distribution of a test statistic. However, all types of null distributions, including the theoretical,…

统计方法学 · 统计学 2021-04-13 Kun He , Mengjie Li , Yan Fu , Fuzhou Gong , Xiaoming Sun

We attempt to recover an $n$-dimensional vector observed in white noise, where $n$ is large and the vector is known to be sparse, but the degree of sparsity is unknown. We consider three different ways of defining sparsity of a vector:…

统计理论 · 数学 2007-06-13 Felix Abramovich , Yoav Benjamini , David L. Donoho , Iain M. Johnstone

Despite the popularity of the false discovery rate (FDR) as an error control metric for large-scale multiple testing, its close Bayesian counterpart the local false discovery rate (lfdr), defined as the posterior probability that a…

统计方法学 · 统计学 2023-09-22 Jake A. Soloff , Daniel Xiang , William Fithian

We propose a general and flexible procedure for testing multiple hypotheses about sequential (or streaming) data that simultaneously controls both the false discovery rate (FDR) and false nondiscovery rate (FNR) under minimal assumptions…

统计方法学 · 统计学 2019-01-14 Jay Bartroff , Jinlin Song

Controlling False Discovery Rate (FDR) while leveraging the side information of multiple hypothesis testing is an emerging research topic in modern data science. Existing methods rely on the test-level covariates while ignoring metrics…

机器学习 · 统计学 2022-10-10 Lin Qiu , Nils Murrugarra-Llerena , Vítor Silva , Lin Lin , Vernon M. Chinchilli

We propose a unified theoretical framework for studying the robustness of the model-X knockoffs framework by investigating the asymptotic false discovery rate (FDR) control of the practically implemented approximate knockoffs procedure.…

机器学习 · 统计学 2025-02-11 Yingying Fan , Lan Gao , Jinchi Lv , Xiaocong Xu

Multiple hypothesis testing is a fundamental problem in high dimensional inference, with wide applications in many scientific fields. In genome-wide association studies, tens of thousands of tests are performed simultaneously to find if any…

统计方法学 · 统计学 2011-11-16 Jianqing Fan , Xu Han , Weijie Gu

The large bulk of work in multiple testing has focused on specifying procedures that control the false discovery rate (FDR), with relatively less attention being paid to the corresponding Type II error known as the false non-discovery rate…

统计理论 · 数学 2020-05-11 Max Rabinovich , Michael I. Jordan , Martin J. Wainwright

Complex large-scale studies, such as those related to microarray data and fMRI studies, often involve testing multiple hierarchically ordered hypotheses. However, most existing false discovery rate (FDR) controlling procedures do not…

统计方法学 · 统计学 2016-12-15 Gavin Lynch , Wenge Guo

We develop a flexible feature selection framework based on deep neural networks that approximately controls the false discovery rate (FDR), a measure of Type-I error. The method applies to architectures whose first layer is fully connected.…

机器学习 · 统计学 2026-02-10 Kazuma Sawaya

When testing many hypotheses, often we do not have strong expectations about the directions of the effects. In some situations however, the alternative hypotheses are that the parameters lie in a certain direction or interval, and it is in…

统计方法学 · 统计学 2026-03-02 Jesse Hemerik

The Model-X knockoff procedure has recently emerged as a powerful approach for feature selection with statistical guarantees. The advantage of knockoff is that if we have a good model of the features X, then we can identify salient features…

机器学习 · 统计学 2019-05-30 Jaime Roquero Gimenez , James Zou

In many scenarios such as genome-wide association studies where dependences between variables commonly exist, it is often of interest to infer the interaction effects in the model. However, testing pairwise interactions among millions of…

统计方法学 · 统计学 2022-09-02 Jingyi Duan , Yang Ning , Xi Chen , Yong Chen

In a one-way analysis-of-variance (ANOVA) model, the number of all pairwise comparisons can be large even when there are only a moderate number of groups. Motivated by this, we consider a regime with a growing number of groups, and prove…

统计理论 · 数学 2023-12-12 Weidong Liu , Dennis Leung , Qiman Shao

Multiple hypothesis testing often involves composite nulls, i.e., nulls that are associated with two or more distributions. In many cases, it is reasonable to assume that there is a prior distribution on the distributions despite it is…

统计理论 · 数学 2008-07-31 Zhiyi Chi

We study asymptotic properties of Bayesian multiple testing procedures and provide sufficient conditions for strong consistency under general dependence structure. We also consider a novel Bayesian multiple testing procedure and associated…

统计理论 · 数学 2020-05-15 Noirrit K. Chandra , Sourabh Bhattacharya

The problem of selecting a handful of truly relevant variables in supervised machine learning algorithms is a challenging problem in terms of untestable assumptions that must hold and unavailability of theoretical assurances that selection…

统计方法学 · 统计学 2023-11-10 Mehdi Rostami , Olli Saarela

False discovery rate (FDR) procedures provide misleading inference when testing multiple null hypotheses with heterogeneous multinomial data. For example, in the motivating study the goal is to identify species of bacteria near the roots of…

统计方法学 · 统计学 2015-11-05 Joshua Habiger , David Watts , Michael Anderson

Consider the problem of testing multiple null hypotheses. A classical approach to dealing with the multiplicity problem is to restrict attention to procedures that control the familywise error rate ($FWER$), the probability of even one…

统计理论 · 数学 2007-06-13 Joseph P. Romano , Azeem M. Shaikh