相关论文: Human ovarian reserve from conception to the menop…

Background: Anti-Mullerian hormone (AMH) is a product of growing ovarian follicles. The concentration of AMH in blood may also reflect the non-growing follicle (NGF) population, i.e. the ovarian reserve, and be of value in predicting…

The measurement of ovarian volume has been shown to be a useful indirect indicator of the ovarian reserve in women of reproductive age, in the diagnosis and management of a number of disorders of puberty and adult reproductive function, and…

Human ovarian reserve is defined by the population of nongrowing follicles (NGFs) in the ovary. Direct estimation of ovarian reserve involves the identification of NGFs in prepared ovarian tissue. Previous studies involving human tissue…

Great apes, the other living members of our hominid family, become decrepit before the age of forty and rarely outlive their fertile years. In contrast, women - even in high mortality hunter-gatherer populations - usually remain healthy and…

During each ovarian cycle, only a definite number of follicles ovulate, while the others undergo a degeneration process called atresia. We have designed a multi-scale mathematical model where ovulation and atresia result from a hormonal…

In this paper, we study a vector conservation law that models the growth and selection of ovarian follicles. During each ovarian cycle, only a definite number of follicles ovulate, while the others undergo a degeneration process called…

Background:Adverse reproductive history is a multisystemic risk factor, but evidence is constrained by isolated outcome studies, limited adjustment, and non-interpretable algorithmic models. We re-frame the estimand from prediction to…

Large samples of globular clusters (GC) with precise multi-wavelength photometry are becoming increasingly available and can be used to constrain the formation history of galaxies. We present the results of an analysis of Milky Way (MW) and…

Abortion is one of the biggest causes of maternal deaths, accounting for 15% of maternal deaths in Southeast Asia. The increase in and effectiveness of using contraception are still considered to be the effective method to reduce abortion…

Fertility differentials by urban-rural residence and nativity of women in Australia significantly impact population composition at sub-national levels. We aim to provide consistent fertility forecasts for Australian women characterized by…

Age-specific fertility rates (ASFRs) provide the most extensive record of reproductive change, but their aggregate nature obscures the individual-level behavioral mechanisms that drive fertility trends. To bridge this micro-macro divide, we…

The size of mature oocytes is similar across mammalian species, yet the size of ovarian follicles increases with species size, with some ovarian follicles reaching diameters more than 1000-fold the size of the enclosed oocyte. Here we show…

In previous contributions, we have presented an analytical model describing the evolution of molecular clouds (MCs) undergoing hierarchical gravitational contraction. The cloud's evolution is characterized by an initial increase in its…

In mammals, female germ cells are sheltered within somatic structures called ovarian follicles, which remain in a quiescent state until they get activated, all along reproductive life. We investigate the sequence of somatic cell events…

The grandmother hypothesis is the most influential account of the evolution of menopause in humans, but other theories warrant investigation. Here I use simulations to investigate two theories that ground the evolution of menopause in…

Nitrogen isotope analysis of bone collagen has been used to reconstruct the breastfeeding practices of archaeological human populations. However, weaning ages have been estimated subjectively because of a lack of both information on…

Breast cancer incidence rises with age and peaks across the menopausal transition, yet why some postmenopausal lobules persist, and why that persistence predicts cancer risk, remains unresolved. Incomplete age-related lobular involution is…

The face is a rich source of information that can be utilized to infer a person's biological age, sex, phenotype, genetic defects, and health status. All of these factors are relevant for predicting an individual's remaining lifespan. In…

Aims. We aim to investigate the stellar population properties, ages, and metal content of the globular clusters (GCs) in NGC 3311, the central galaxy of the Hydra I cluster, to better constrain its evolution history. Methods. We used…

Extensive post reproductive lifespan (PRLS) is observed only in a few species, such as humans or resident killer whales, and its origin is under debate. Hypotheses like mother-care and grandmother-care invoke strategies of…