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相关论文: Performance guarantees for individualized treatmen…

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Estimating treatment effects from observational data is of central interest across numerous application domains. Individual treatment effect offers the most granular measure of treatment effect on an individual level, and is the most useful…

机器学习 · 统计学 2024-08-06 Hengrui Cai , Huaqing Jin , Lexin Li

In personalised decision making, evidence is required to determine whether an action (treatment) is suitable for an individual. Such evidence can be obtained by modelling treatment effect heterogeneity in subgroups. The existing…

统计方法学 · 统计学 2022-06-24 Jiuyong Li , Lin Liu , Shisheng Zhang , Saisai Ma , Thuc Duy Le , Jixue Liu

Practitioners in medicine, business, political science, and other fields are increasingly aware that decisions should be personalized to each patient, customer, or voter. A given treatment (e.g. a drug or advertisement) should be…

机器学习 · 统计学 2018-06-15 Alejandro Schuler , Michael Baiocchi , Robert Tibshirani , Nigam Shah

Learning individualized treatment rules (ITRs) is an important topic in precision medicine. Current literature mainly focuses on deriving ITRs from a single source population. We consider the observational data setting when the source…

机器学习 · 统计学 2023-07-04 Rui Chen , Jared D. Huling , Guanhua Chen , Menggang Yu

The individualized treatment rule (ITR), which recommends an optimal treatment based on individual characteristics, has drawn considerable interest from many areas such as precision medicine, personalized education, and personalized…

统计方法学 · 统计学 2023-09-28 Qi Xu , Haoda Fu , Annie Qu

A dynamic treatment regime is a sequence of treatment decision rules tailored to an individual's evolving status over time. In precision medicine, much focus has been placed on finding an optimal dynamic treatment regime which, if followed…

其他统计学 · 统计学 2025-10-13 Chunyu Wang , Brian DM Tom

Variable selection for optimal treatment regime in a clinical trial or an observational study is getting more attention. Most existing variable selection techniques focused on selecting variables that are important for prediction, therefore…

统计方法学 · 统计学 2014-05-22 Ailin Fan , Wenbin Lu , Rui Song

Conditional independence of treatment assignment from potential outcomes is a commonly used but nonrefutable assumption. We derive identified sets for various treatment effect parameters under nonparametric deviations from this conditional…

统计方法学 · 统计学 2017-10-25 Matthew A. Masten , Alexandre Poirier

One primary goal of precision medicine is to estimate the individualized treatment rules (ITRs) that optimize patients' health outcomes based on individual characteristics. Health studies with multiple treatments are commonly seen in…

统计方法学 · 统计学 2025-05-07 Xuqiao Li , Qiuyan Zhou , Ying Wu , Ying Yan

We present methodological advances in understanding the effectiveness of personalized medicine models and supply easy-to-use open-source software. Personalized medicine involves the systematic use of individual patient characteristics to…

统计方法学 · 统计学 2021-06-01 Adam Kapelner , Justin Bleich , Alina Levine , Zachary D. Cohen , Robert J. DeRubeis , Richard Berk

Estimating individualized treatment rules is a central task for personalized medicine. [zhao2012estimating] and [zhang2012robust] proposed outcome weighted learning to estimate individualized treatment rules directly through maximizing the…

统计方法学 · 统计学 2017-10-02 Yifan Cui , Ruoqing Zhu , Michael Kosorok

Dynamic treatment regimes have been proposed to personalize treatment decisions by utilizing historical patient data, but they may not always improve on the current standard of care. It is thus meaningful to integrate the standard of care…

应用统计 · 统计学 2025-12-11 Johannes Hruza , Arvid Sjölander , Erin Gabriel , Samir Bhatt , Michael Sachs

Suppose we have a binary treatment used to influence an outcome. Given data from an observational or controlled study, we wish to determine whether or not there exists some subset of observed covariates in which the treatment is more…

统计方法学 · 统计学 2016-03-22 Alexander R. Luedtke , Mark J. van der Laan

A central goal of modern causal inference is estimating heterogeneous treatment effects to answer questions like "how does an intervention affect each unit," rather than only on average. We study this problem with panel-data where we…

机器学习 · 统计学 2026-05-29 Anay Mehrotra , Phuc Tran , Van H. Vu , Manolis Zampetakis

Dynamic treatment regimes are sequential decision rules that adapt treatment according to individual time-varying characteristics and outcomes to achieve optimal effects, with applications in precision medicine, personalized…

统计方法学 · 统计学 2025-10-24 Yuanshan Gao , Yang Bai , Yifan Cui

In many decision-making problems, the primary outcome is expensive, time-consuming, or difficult to observe, so individualized treatment rules (ITRs) may be instead learned from surrogate endpoints. However, a surrogate that is highly…

统计方法学 · 统计学 2026-04-13 Zeyu Xu , Xiaojie Mao , Hao Mei , Yue Liu

Estimating individualized treatment rules - particularly in the context of right-censored outcomes - is challenging because the treatment effect heterogeneity of interest is often small, thus difficult to detect. While this motivates the…

We consider estimation of an optimal individualized treatment rule from observational and randomized studies when a high-dimensional vector of baseline variables is available. Our optimality criterion is with respect to delaying expected…

统计方法学 · 统计学 2017-11-09 Iván Díaz , Oleksandr Savenkov , Karla Ballman

Estimating heterogeneous treatment effects is central to data-driven decision-making, yet industrial applications often face a fundamental tension between limited randomized controlled trial (RCT) budgets and abundant but biased…

统计方法学 · 统计学 2026-02-26 Jiacan Gao , Xinyan Su , Mingyuan Ma , Yiyan Huang , Xiao Xu , Xinrui Wan , Tianqi Gu , Enyun Yu , Jiecheng Guo , Zhiheng Zhang

We seek to understand the probability an individual benefits from treatment (PIBT), an inestimable quantity that must be bounded in practice. Given the innate uncertainty in the population-level bounds on PIBT, we seek to better understand…

统计方法学 · 统计学 2024-04-04 Gabriel Ruiz , Oscar Hernan Madrid Padilla