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Bidirectional variants of stochastic many particle models for transport by molecular motors show a strong tendency to form macroscopic clusters on static lattices. Inspired by the fact that the microscopic tracks for molecular motors are…

生物物理 · 物理学 2013-05-29 M. Ebbinghaus , C. Appert-Rolland , L. Santen

We introduce a stochastic lattice gas model including two particle species and two parallel lanes. One lane with exclusion interaction and directed motion and the other lane without exclusion and unbiased diffusion, mimicking a micotubule…

统计力学 · 物理学 2009-11-13 M. Ebbinghaus , L. Santen

Within cells, vesicles and proteins are actively transported several micrometers along the cytoskeletal filaments. The transport along microtubules is propelled by dynein and kinesin motors, which carry the cargo in opposite directions.…

生物物理 · 物理学 2020-05-20 Robin Jose , Ludger Santen

Many biological processes are supported by special molecules, called motor proteins or molecular motors, that transport cellular cargoes along linear protein filaments and can reversibly associate to their tracks. Stimulated by these…

统计力学 · 物理学 2021-11-17 Akriti Jindal , Anatoly B. Kolomeisky , Arvind Kumar Gupta

We present a two channel driven lattice gas model with oppositely directed species moving on two parallel lanes with lane switching processes. We study correlated lane switching mechanism for particles so that switching may occur with…

统计力学 · 物理学 2015-05-28 Sudipto Muhuri , Ignacio Pagonabarraga

The transport of motile entities across modulated energy landscapes plays an important role in a range of phenomena in biology, colloidal science and solid-state physics. Here, an easily implementable strategy that allows for the collective…

软凝聚态物质 · 物理学 2020-03-11 Fernando Martínez-Pedrero , Francisco Ortega , Ramón G. Rubio , Carles Calero

Several theoretical models based on totally asymmetric simple exclusion process (TASEP) have been extensively utilized to study various non-equilibrium transport phenomena. Inspired by the the role of microtubule-transported vesicles in…

统计力学 · 物理学 2021-02-03 Akriti Jindal , Atul Kumar Verma , Arvind Kumar Gupta

We investigate a driven two-channel system where particles on different lanes mutually obstruct each others motion extending an earlier model by Popkov and Peschel [1]. This obstruction may occur in biological contexts due to steric…

生物物理 · 物理学 2015-03-13 Anna Melbinger , Tobias Reichenbach , Thomas Franosch , Erwin Frey

In this paper, we introduce an ASEP-like transport model for bidirectional motion of particles on a multi-lane lattice. The model is motivated by {\em in vivo} experiments on organelle motility along a microtubule (MT), consisting of…

元胞自动机与格子气 · 物理学 2015-05-28 Congping Lin , Gero Steinberg , Peter Ashwin

The flow of motor proteins on a filamental track is modelled within the the framework of lattice driven diffusive systems. Motors, considered as hopping particles, perform a highly biased asymmetric exclusion process when bound to the…

统计力学 · 物理学 2007-05-23 M. Ebrahim Fouladvand , Modjtaba Salehi , Mostafa Yadegari

We introduce a multi-species lattice gas model for motor protein driven collective cargo transport on cellular filaments. We use this model to describe and analyze the collective motion of interacting vesicle cargoes being carried by…

统计力学 · 物理学 2010-09-10 Sudipto Muhuri , Ignacio Pagonabarraga

The motion of molecules across channels is critically important for understanding mechanisms of cellular processes. Here we investigate the mechanism of interactions in the molecular transport by analyzing exactly solvable discrete…

软凝聚态物质 · 物理学 2015-05-18 Anatoly B. Kolomeisky , Karthik Uppulury

Transport of molecular motors along protein filaments in a half-closed geometry is a common feature of biologically relevant processes in cellular protrusions. Using a lattice gas model we study how the interplay between active and…

生物物理 · 物理学 2017-03-30 Isabella R. Graf , Erwin Frey

Here we study a driven lattice gas model for microtubule depolymerizing molecular motors, where traffic jams of motors induce stochastic switching between microtubule growth and shrinkage. We term this phenomenon \enquote{traffic dynamic…

统计力学 · 物理学 2015-05-07 Louis Reese , Anna Melbinger , Erwin Frey

With the recent production of polar molecules in the quantum regime, long-range dipolar interactions are expected to facilitate the understanding of strongly interacting many-body quantum systems and to realize lattice spin models for…

Biological transport is supported by collective dynamics of enzymatic molecules that are called motor proteins or molecular motors. Experiments suggest that motor proteins interact locally via short-range potentials. We investigate the…

统计力学 · 物理学 2015-06-18 Hamid Teimouri , Anatoly B. Kolomeisky , Kareem Mehrabiani

Many transport processes in nature take place on substrates, often considered as unidimensional lanes. These unidimensional substrates are typically non-static: affected by a fluctuating environment, they can undergo conformational changes.…

Motivated by experimental results on the interplay between molecular motors and tau proteins, we extend lattice-based models of intracellular transport to include a second species of particle which locally influences the motor-filament…

亚细胞过程 · 定量生物学 2010-04-27 H. Grzeschik , R. J. Harris , L. Santen

Driven non-equilibrium lattice models have wide-ranging applications in contexts such as mass transport, traffic flow, and transport in biological systems. In this work, we investigate the steady-state properties of a one-dimensional…

统计力学 · 物理学 2026-01-16 Swastik Majumder , Mustansir Barma

Natural phenomena frequently involve a very large number of interacting molecules moving in confined regions of space. Cellular transport by motor proteins is an example of such collective behavior. We derive a deterministic compartmental…

亚细胞过程 · 定量生物学 2017-11-01 Yoram Zarai , Michael Margaliot , Anatoly B. Kolomeisky
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