相关论文: Domain formation in membranes with quenched protei…
In experiments on model membranes, a formation of large domains of different lipid composition is readily observed. However, no such phase separation is observed in the membranes of intact cells. Instead, a structure of small transient…
With Monte Carlo methods, we investigate the universality class of the depinning transition in the two-dimensional Ising model with quenched random fields. Based on the short-time dynamic approach, we accurately determine the depinning…
Lipid rafts are heterogeneous dynamic lipid domains of the cell membranes that are involved in several biological processes, like protein and lipids specific transport and signaling. Our understanding of lipid raft formation is still…
In the context of Monte Carlo simulations, the analysis of the probability distribution $P_L(m)$ of the order parameter $m$, as obtained in simulation boxes of finite linear extension $L$, allows for an easy estimation of the location of…
The domain formation of curvature-inducing molecules, such as peripheral or transmembrane proteins and conical surfactants, is studied in thermal equilibrium and nonequilibrium steady states using meshless membrane simulations. These…
Lipid phase heterogeneity in the plasma membrane is thought to be crucial for many aspects of cell signaling, but the physical basis of participating membrane domains such as "lipid rafts" remains controversial. Here we consider a lattice…
Multi-component membranes such as ternary mixtures of lipids and cholesterol can exhibit coexistence regions between two liquid phases. When such membranes adhere to a corrugated substrate, the phase separation process strongly depends on…
Many of the processes that underly neural computation are carried out by ion channels embedded in the plasma membrane, a two-dimensional liquid that surrounds all cells. Recent experiments have demonstrated that this membrane is poised…
We discuss a realistic scenario, accounting for the existence of sub-micrometric protein domains in cell membranes. At the biological level, such membrane domains have been shown to be specialized, in order to perform a determined…
Using high-precision Monte-Carlo simulations based on a parallel version of the Wang-Landau algorithm and finite-size scaling techniques we study the effect of quenched disorder in the crystal-field coupling of the Blume-Capel model on the…
We investigate how an externally imposed curvature influences lipid segregation on two-phase-coexistent membranes. We show that the bending-modulus contrast of the two phases and the curvature act together to yield a reduced effective line…
We propose a model that accounts for the budding transition of asymmetric two-component lipid domains, where the two monolayers (leaflets) have different average compositions controlled by independent chemical potentials. Assuming a…
With large-scale Monte Carlo simulations, we investigate the nonsteady relaxation at the dynamic depinning transition in the two-dimensional Gaussian random-field Ising model. The dynamic scaling behavior is carefully analyzed, and the…
We introduce an approach to derive an effective scalar field theory for the glass transition; the fluctuating field is the overlap between equilibrium configurations. We apply it to the case of constrained liquids for which the introduction…
We analyze critical points that can be induced in glassy systems by the presence of constraints. These critical points are predicted by the Mean Field Thermodynamic approach and they are precursors of the standard glass transition in…
We study the two-dimensional Ising model on a network with a novel type of quenched topological (connectivity) disorder. We construct random lattices of constant coordination number and perform large scale Monte Carlo simulations in order…
Theoretical models describing specific adhesion of membranes predict (for certain parameters) a macroscopic phase separation of bonds into adhesion domains. We show that this behavior is fundamentally altered if the membrane is pinned…
Usually, the impact of structural disorder on the magnetic phase transition in the 3D Ising model is analyzed within the framework of quenched dilution by a non-magnetic component, where some lattice sites are occupied by Ising spins, while…
Specific lipid environments are necessary for the establishment of protein signalling platforms in membranes, yet their origin has been highly debated. We present a continuum, exactly solvable model of protein induced local demixing of…
Quenched or frozen-in structural disorder is ubiquitous in real experimental systems. Much of the progress is achieved in understanding the phase separation of such systems using the diffusion-driven coarsening in Ising model with quenched…