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This workshop explores the interface between cognitive neuroscience and recent advances in AI fields that aim to reproduce human performance such as natural language processing and computer vision, and specifically deep learning approaches…

Although non-canonical residues, caps, crosslinks, and nicks play an important role in the function of many DNA, RNA, proteins, and complexes, we do not fully understand how networks of non-canonical macromolecules generate behavior. One…

This volume contains the post-proceedings of the Thirteenth International Workshop on Graph Computation Models (GCM 2022). The workshop took place in Nantes, France on 6th July 2022 as part of STAF 2022 (Software Technologies: Applications…

计算机科学中的逻辑 · 计算机科学 2022-12-22 Reiko Heckel , Christopher M. Poskitt

In many cellular signaling pathways, key components form clusters at the cell membrane. Although much work has focused on the mechanisms behind such cluster formation, the implications for downstream signaling remain poorly understood.…

分子网络 · 定量生物学 2012-03-14 Andrew Mugler , Aimee Gotway Bailey , Koichi Takahashi , Pieter Rein ten Wolde

In this paper a novel biclustering algorithm based on artificial intelligence (AI) is introduced. The method called EBIC aims to detect biologically meaningful, order-preserving patterns in complex data. The proposed algorithm is probably…

机器学习 · 计算机科学 2018-07-27 Patryk Orzechowski , Moshe Sipper , Xiuzhen Huang , Jason H. Moore

Modeling membrane interactions with arbitrarily shaped colloidal particles, such as environmental micro- and nanoplastics, at the cell scale remains particularly challenging, owing to the complexity of particle geometries and the need to…

软凝聚态物质 · 物理学 2025-09-15 Didarul Ahasan Redwan , Justin Reicher , Xin Yong

Driven by the critical needs of biomanufacturing 4.0, we introduce a probabilistic knowledge graph hybrid model characterizing the risk- and science-based understanding of bioprocess mechanisms. It can faithfully capture the important…

机器学习 · 统计学 2022-10-03 Wei Xie , Keqi Wang , Hua Zheng , Ben Feng

Many biological, physical, and social interactions have a particular dependence on where they take place. In living cells, protein movement between the nucleus and cytoplasm affects cellular response (i.e., proteins must be present in the…

分子网络 · 定量生物学 2012-10-11 Heather A. Harrington , Elisenda Feliu , Carsten Wiuf , Michael M. P. Stumpf

Recent years have witnessed the growing scholarly interest in the next-generation general-purpose computers. Various innovative computing modes have been proposed, such as optical, quantum phenomena, and DNA-based modes. Sequential logic…

新兴技术 · 计算机科学 2026-01-01 Han Huang , Chengzhi Ma , Yuxin Zhao , Qingyao Wang , Xinglong Xiao , Xiulin Shu , Zhifeng Hao

We develop a (co)algebraic framework to study a family of process calculi with monadic branching structures and recursion operators. Our framework features a uniform semantics of process terms and a complete axiomatisation of semantic…

计算机科学中的逻辑 · 计算机科学 2022-07-26 Todd Schmid , Wojciech Rozowski , Alexandra Silva , Jurriaan Rot

Computational models have become one of the prevalent methods to model complex phenomena. To accurately model complex interactions, such as detailed biomolecular interactions, scientists often rely on multiscale models comprised of several…

The nature of distributed computation has often been described in terms of the component operations of universal computation: information storage, transfer and modification. We review the first complete framework that quantifies each of…

元胞自动机与格子气 · 物理学 2014-01-23 Joseph T. Lizier , Mikhail Prokopenko , Albert Y. Zomaya

Action languages have emerged as an important field of Knowledge Representation for reasoning about change and causality in dynamic domains. This article presents Cerbere, a production system designed to perform online causal, temporal and…

人工智能 · 计算机科学 2020-02-19 Theodore Patkos , Dimitris Plexousakis , Abdelghani Chibani , Yacine Amirat

This series presents an approach to mathematical biology which makes precise the function of biological molecules. Because biological systems compute, the theory is a general purpose computer language. I build a language for efficiently…

分子网络 · 定量生物学 2007-05-23 Ron Maimon

Biological systems, from a cell to the human brain, are inherently complex. A powerful representation of such systems, described by an intricate web of relationships across multiple scales, is provided by complex networks. Recently, several…

定量方法 · 定量生物学 2018-02-06 M. De Domenico

While experiments and computer simulations to study biological phenomena are usually performed in diluted in vitro conditions, such phenomena happen inside the cell, an environment densely packed with diverse macromolecules. Here, we revise…

生物大分子 · 定量生物学 2026-05-22 Apoorva Mathur , Vanessa Regina Miranda , Ariane Nunes-Alves

This is the proceedings of PLACES'10, the 3rd Workshop on Programming Language Approaches to Concurrency and Communication-cEntric Software, held in Pathos, Cyprus, on 21st Mach, 2010, co-located with the ETAPS federated conferences. PLACES…

编程语言 · 计算机科学 2011-10-19 Kohei Honda , Alan Mycroft

In this work, we review previously developed coarse-grained (CG) particle models for biological membrane and red blood cells (RBCs) and discuss the advantages of the CG particle method over the continuum and atomic simulations on modeling…

软凝聚态物质 · 物理学 2017-07-18 He Li , Hung-yu Chang , Jun Yang , Lu Lu , George Lykotrafitis

This chapter summarizes several approaches combining theory, simulation and experiment that aim for a better understanding of phenomena in lipid bilayers and membrane protein systems, covering topics such as lipid rafts, membrane mediated…

生物物理 · 物理学 2014-12-17 Markus Deserno , Kurt Kremer , Harald Paulsen , Christine Peter , Friederike Schmid

Deciphering the control principles of metabolism and its interaction with other cellular functions is central to biomedicine and biotechnology. Yet, understanding the efficient control of metabolic fluxes remains elusive for large-scale…

分子网络 · 定量生物学 2015-09-04 Georg Basler , Zoran Nikoloski , Abdelhalim Larhlimi , Albert-László Barabási , Yang-Yu Liu
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