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In Diffusive Molecular Communication (DMC), information is transmitted by diffusing molecules. Synaptic signaling, as a natural implementation of this paradigm, encompasses functional components that, once understood, can facilitate the…

亚细胞过程 · 定量生物学 2020-11-26 Sebastian Lotter , Arman Ahmadzadeh , Robert Schober

Spiking neural networks (SNNs) receive widespread attention because of their low-power hardware characteristic and brain-like signal response mechanism, but currently, the performance of SNNs is still behind Artificial Neural Networks…

神经与进化计算 · 计算机科学 2021-05-07 Xingyu Yang , Mingyuan Meng , Shanlin Xiao , Zhiyi Yu

Synaptic plasticity, the dynamic tuning of signal transmission strength between neurons, serves as a fundamental basis for memory and learning in biological organisms. This adaptive nature of synapses is considered one of the key features…

介观与纳米尺度物理 · 物理学 2024-11-11 Yechan Noh , Alex Smolyanitsky

We present an effective model for timing-dependent synaptic plasticity (STDP) in terms of two interacting traces, corresponding to the fraction of activated NMDA receptors and the Ca2+ concentration in the dendritic spine of the…

神经元与认知 · 定量生物学 2015-02-26 Rodrigo Echeveste , Claudius Gros

The lateral diffusion and trapping of neurotransmitter receptors within the postsynaptic membrane of a neuron plays a key role in determining synaptic strength and plasticity. Trapping is mediated by the reversible binding of receptors to…

定量方法 · 定量生物学 2022-03-25 Ryan D. Schumm , Paul C. Bressloff

Spiking neural networks (SNNs) employing unsupervised learning methods inspired by neural plasticity are expected to be a new framework for artificial intelligence. In this study, we investigated the effect of multiple types of neural…

神经与进化计算 · 计算机科学 2026-01-19 Shinnosuke Touda , Hirotsugu Okuno

Brain-inspired spiking neural networks (SNNs) are recognized as a promising avenue for achieving efficient, low-energy neuromorphic computing. Recent advancements have focused on directly training high-performance SNNs by estimating the…

神经与进化计算 · 计算机科学 2025-05-20 Jiaqiang Jiang , Lei Wang , Runhao Jiang , Jing Fan , Rui Yan

Spiking neurons can perform spatiotemporal feature detection by nonlinear synaptic and dendritic integration of presynaptic spike patterns. Multicompartment models of non-linear dendrites and related neuromorphic circuit designs enable…

神经与进化计算 · 计算机科学 2021-06-02 Mattias Nilsson , Foteini Liwicki , Fredrik Sandin

We investigate the efficient transmission and processing of weak, subthreshold signals in a realistic neural medium in the presence of different levels of the underlying noise. Assuming Hebbian weights for maximal synaptic conductances --…

生物物理 · 物理学 2015-08-19 Joaquin J. Torres , Irene Elices , J. Marro

The functional significance of correlations between action potentials of neurons is still a matter of vivid debates. In particular it is presently unclear how much synchrony is caused by afferent synchronized events and how much is…

神经元与认知 · 定量生物学 2013-04-09 Matthias Schultze-Kraft , Markus Diesmann , Sonja Grün , Moritz Helias

Neural oscillations can enhance feature recognition, modulate interactions between neurons, and improve learning and memory. Simulational studies have shown that coherent oscillations give rise to windows in time during which information…

神经元与认知 · 定量生物学 2014-10-07 Andrew T. Sornborger , Louis Tao

Synaptic memory is considered to be the main element responsible for learning and cognition in humans. Although traditionally non-volatile long-term plasticity changes have been implemented in nanoelectronic synapses for neuromorphic…

新兴技术 · 计算机科学 2017-12-20 Abhronil Sengupta , Kaushik Roy

Neuronal networking supports complex brain functions, with neurotransmitters facilitating communication through chemical synapses. The release probability of neurotransmitters varies and is influenced by pre-synaptic neuronal activity.…

神经元与认知 · 定量生物学 2024-06-12 Zihan Liu , Flavia Nathaline Chanentia , Patteera Supvithayanong , Chi Chung Alan Fung

In this paper we present a biologically detailed mathematical model of tripartite synapses, where astrocytes modulate short-term synaptic plasticity. The model consists of a pre-synaptic bouton, a post-synaptic dendritic spine-head, a…

神经元与认知 · 定量生物学 2012-06-05 Shivendra Tewari , Kaushik Majumdar

In the mammalian nervous system, various synaptic plasticity rules act, either individually or synergistically, and over wide-ranging timescales to dictate the processes that enable learning and memory formation. To mimic biological…

无序系统与神经网络 · 物理学 2021-06-11 Syed Ghazi Sarwat , Benedikt Kersting , Timoleon Moraitis , Vara Prasad Jonnalagadda , Abu Sebastian

Synaptic connections are known to change dynamically. High-frequency presynaptic inputs induce decrease of synaptic weights. This process is known as short-term synaptic depression. The synaptic depression controls a gain for presynaptic…

无序系统与神经网络 · 物理学 2007-05-23 Narihisa Matsumoto , Daisuke Ide , Masataka Watanabe , Masato Okada

As a means of dynamically reconfiguring the synaptic weight of a superconducting optoelectronic loop neuron, a superconducting flux storage loop is inductively coupled to the synaptic current bias of the neuron. A standard flux memory cell…

Due to the point-like nature of neuronal spiking, efficient neural network simulators often employ event-based simulation schemes for synapses. Yet many types of synaptic plasticity rely on the membrane potential of the postsynaptic cell as…

神经元与认知 · 定量生物学 2022-04-05 Jonas Stapmanns , Jan Hahne , Moritz Helias , Matthias Bolten , Markus Diesmann , David Dahmen

Due to many limitations of Von Neumann architecture such as speed, memory bandwidth, efficiency of global interconnects and increase in the application of artificial neural network, researchers have been pushed to look into alternative…

新兴技术 · 计算机科学 2019-05-15 Harshit Roy , Mrigank Sharad

Sensory information propagates through successive processing stages in the brain, where synaptic weight patterns between stations determine how downstream neurons decode information from upstream populations. Although optimized synaptic…

神经元与认知 · 定量生物学 2026-02-26 Ori Hendler , Ronen Segev , Maoz Shamir