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Spike-based learning with memristive devices in neuromorphic computing architectures typically uses learning circuits that require overlapping pulses from pre- and post-synaptic nodes. This imposes severe constraints on the length of the…

新兴技术 · 计算机科学 2017-11-07 Manu V Nair , Lorenz K. Muller , Giacomo Indiveri

Collective rhythmic dynamics from neurons is vital for cognitive functions such as memory formation but how neurons self-organize to produce such activity is not well understood. Attractor-based models have been successfully implemented as…

神经元与认知 · 定量生物学 2013-03-22 Mark Niedringhaus , Xin Chen , Katherine Conant , Rhonda Dzakpasu

Neurons have the capability of transforming information from a digital signal at the dendrites of the presynaptic termi- nal to an analogous wave at the synaptic cleft and back to a digital pulse when they achieve the required voltage for…

生物物理 · 物理学 2018-10-19 Alexandra Pinto Castellanos

Synaptic plasticity is a key component of neuronal dynamics, describing the process by which the connections between neurons change in response to experiences. In this study, we extend a network model of $\theta$-neuron oscillators to…

神经元与认知 · 定量生物学 2024-08-01 Niamh Fennelly , Alannah Neff , Renaud Lambiotte , Andrew Keane , Áine Byrne

The synapse is a key element of neuromorphic computing in terms of efficiency and accuracy. In this paper, an optimized current-controlled memristive synapse circuit is proposed. Our proposed synapse demonstrates reliability in the face of…

Learning is based on synaptic plasticity, which affects and is driven by neural activity. Because pre- and postsynaptic spiking activity is shaped by randomness, the synaptic weights follow a stochastic process, requiring a probabilistic…

神经元与认知 · 定量生物学 2026-01-14 Jakob Stubenrauch , Naomi Auer , Richard Kempter , Benjamin Lindner

One of the central problems in neuroscience is reconstructing synaptic connectivity in neural circuits. Synapses onto a neuron can be probed by sequentially stimulating potentially pre-synaptic neurons while monitoring the membrane voltage…

神经元与认知 · 定量生物学 2012-10-05 Tao Hu , Dmitri B. Chklovskii

Short-term synaptic plasticity (STP) is often regarded as a presynaptic filter of spikes, independent of postsynaptic activity. Recent experiments, however, indicate an associative STP that depends on pre- and postsynaptic coactivation. We…

神经元与认知 · 定量生物学 2026-05-20 Genki Shimizu , Taro Toyoizumi

The computational efficiency of the human brain is believed to stem from the parallel information processing capability of neurons with integrated storage in synaptic interconnections programmed by local spike triggered learning rules such…

新兴技术 · 计算机科学 2020-03-17 S. R. Nandakumar , Bipin Rajendran

Previous experimental work has shown high-frequency Poisson-distributed trains of combined excitatory and inhibitory conductance- and current-based synaptic inputs reduce amplitude of subthreshold oscillations of SCs. In this paper, we…

神经元与认知 · 定量生物学 2018-05-08 Dongwook Kim

In timing-based neural codes, neurons have to emit action potentials at precise moments in time. We use a supervised learning paradigm to derive a synaptic update rule that optimizes via gradient ascent the likelihood of postsynaptic firing…

神经元与认知 · 定量生物学 2007-05-23 Jean-Pascal Pfister , Taro Toyoizumi , David Barber , Wulfram Gerstner

Learning in the brain requires complementary mechanisms: potentiation and activity-dependent homeostatic scaling. We introduce synaptic scaling to a biologically-realistic spiking model of neocortex which can learn changes in oscillatory…

神经元与认知 · 定量生物学 2013-04-09 Mark Rowan , Samuel Neymotin

The interplay between excitatory and inhibitory neurons imparts rich functions of the brain. To understand the underlying synaptic mechanisms, a fundamental approach is to study the dynamics of excitatory and inhibitory conductances of each…

神经元与认知 · 定量生物学 2017-10-17 Songting Li , Nan Liu , Xiaohui Zhang , Douglas Zhou , David Cai

Membrane receptors for neuromodulators (NM) are highly regulated in their distribution and efficacy - a phenomenon which influences the individual cell's response to central signals of NM release. Even though NM receptor regulation is…

分子网络 · 定量生物学 2007-05-23 Gabriele Scheler

Using a realistic model of activity dependent dynamical synapses and a standard integrate and fire neuron model we study, both analytically and numerically, the conditions in which a postsynaptic neuron efficiently detects temporal…

神经元与认知 · 定量生物学 2007-05-23 Jorge F. Mejias , Joaquin J. Torres

This study proposes voltage-dependent-synaptic plasticity (VDSP), a novel brain-inspired unsupervised local learning rule for the online implementation of Hebb's plasticity mechanism on neuromorphic hardware. The proposed VDSP learning rule…

Short-term presynaptic plasticity designates variations of the amplitude of synaptic information transfer whereby the amount of neurotransmitter released upon presynaptic stimulation changes over seconds as a function of the neuronal firing…

神经元与认知 · 定量生物学 2011-12-06 Maurizio De Pittà , Vladislav Volman , Hugues Berry , Eshel Ben-Jacob

Synaptic communication is studied by communication engineers for two main reasons. One is to enable novel neuroengineering applications that require interfacing with neurons. The other reason is to draw inspiration for the design of…

神经元与认知 · 定量生物学 2023-01-18 Sebastian Lotter , Michael T. Barros , Robert Schober , Maximilian Schäfer

Synapses change on multiple timescales, ranging from milliseconds to minutes, due to a combination of both short- and long-term plasticity. Here we develop an extension of the common Generalized Linear Model to infer both short- and…

神经元与认知 · 定量生物学 2022-08-15 Ganchao Wei , Ian H. Stevenson

We have added a simplified neuromorphic model of Spike Time Dependent Plasticity (STDP) to the Synapto-dendritic Kernel Adapting Neuron (SKAN). The resulting neuron model is the first to show synaptic encoding of afferent signal to noise…

神经与进化计算 · 计算机科学 2014-11-12 Saeed Afshar , Libin George , Jonathan Tapson , Andre van Schaik , Philip de Chazal , Tara Julia Hamilton