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Magnetic Resonance Spectroscopy (MRS) is a noninvasive tool to reveal metabolic information. One challenge of 1H-MRS is the low Signal-Noise Ratio (SNR). To improve the SNR, a typical approach is to perform Signal Averaging (SA) with M…

Carbohydrates, vital components of biological systems, are well-known for their structural diversity. Nuclear Magnetic Resonance (NMR) spectroscopy plays a crucial role in understanding their intricate molecular arrangements and is…

机器学习 · 计算机科学 2023-11-22 Maria Bånkestad , Keven M. Dorst , Göran Widmalm , Jerk Rönnols

Nuclear Magnetic Resonance (NMR) spectroscopy is an important analytical tool in chemistry, biology, and life science, but it suffers from relatively low sensitivity and long acquisition time. Thus, improving the apparent signal-to-noise…

化学物理 · 物理学 2020-07-27 Tianyu Qiu , Zi Wang , Huiting Liu , Di Guo , Xiaobo Qu

The rich chemical information from tissue metabolomics provides a powerful means to elaborate tissue physiology or tumor characteristics at cellular and tumor microenvironment levels. However, the process of obtaining such information…

Alterations in nuclear morphology are useful adjuncts and even diagnostic tools used by pathologists in the diagnosis and grading of many tumors, particularly malignant tumors. Large datasets such as TCGA and the Human Protein Atlas, in…

Nuclear Magnetic Resonance (NMR) spectroscopy is an important bio-engineering tool to determine the metabolic concentrations, molecule structures and so on. The data acquisition time, however, is very long in multi-dimensional NMR. To…

Nuclear Magnetic Resonance (NMR) spectroscopy is one of the most powerful and widely used tools for molecular structure elucidation in organic chemistry. However, the interpretation of NMR spectra to determine unknown molecular structures…

化学物理 · 物理学 2025-09-03 Yongqi Jin , Jun-Jie Wang , Fanjie Xu , Xiaohong Ji , Zhifeng Gao , Linfeng Zhang , Guolin Ke , Rong Zhu , Weinan E

Nuclear Magnetic Resonance (NMR) spectrometry uses electro-frequency pulses to probe the resonance of a compound's nucleus, which is then analyzed to determine its structure. The acquisition time of high-resolution NMR spectra remains a…

Automation of brain tumor segmentation in 3D magnetic resonance images (MRIs) is key to assess the diagnostic and treatment of the disease. In recent years, convolutional neural networks (CNNs) have shown improved results in the task.…

图像与视频处理 · 电气工程与系统科学 2021-01-01 Laura Mora Ballestar , Veronica Vilaplana

Nuclear Magnetic Resonance (NMR) spectroscopy is the cornerstone of small-molecule structure elucidation. While deep learning has demonstrated significant potential in automating structure elucidation and spectral simulation, current…

计算工程、金融与科学 · 计算机科学 2026-01-23 Zheng Fang , Chen Yang , Hai-tao Yu , Haoming Luo , Haitao He , Jiaqing Xie , Zhuo Yang , Jun Xia

Concerning NMR-based metabolomics, 1D spectra processing often requires an expert eye for disentangling the intertwined peaks, and so far the best way is to proceed interactively with a spectra viewer. NMRProcFlow is a graphical and…

定量方法 · 定量生物学 2016-11-24 Daniel Jacob , Catherine Deborde , Marie Lefebvre , Mickael Maucourt , Anick Moing

The metabolism of an organism is regulated at the cellular level, yet is strongly influenced by its environment. The precise metabolomic study of living organisms is currently hampered by measurement sensitivity: most metabolomic…

定量方法 · 定量生物学 2017-07-28 Jan G. Korvink , Vlad Badilita , Lorenzo Bordonali , Mazin Jouda , Dario Mager , Neil MacKinnon

Medical image analysis using deep neural networks has been actively studied. Deep neural networks are trained by learning data. For accurate training of deep neural networks, the learning data should be sufficient, of good quality, and…

图像与视频处理 · 电气工程与系统科学 2021-01-05 Sunho Kim , Byungjai Kim , HyunWook Park

The complex heterogeneity of brain tumours is increasingly recognized to demand data of magnitudes and richness only fully-inclusive, large-scale collections drawn from routine clinical care could plausibly offer. This is a task…

计算机视觉与模式识别 · 计算机科学 2023-05-01 James K Ruffle , Samia Mohinta , Robert J Gray , Harpreet Hyare , Parashkev Nachev

Nuclear Magnetic Resonance (NMR) spectroscopy is a widely-used technique in the fields of bio-medicine, chemistry, and biology for the analysis of chemicals and proteins. The signals from NMR spectroscopy often have low signal-to-noise…

信号处理 · 电气工程与系统科学 2024-05-21 Zihao Zou , Shirin Shoushtari , Jiaming Liu , Jialiang Zhang , Patrick Judge , Emilia Santana , Alison Lim , Marcus Foston , Ulugbek S. Kamilov

Brain is an organ that controls activities of all the parts of the body. Recognition of automated brain tumor in Magnetic resonance imaging (MRI) is a difficult task due to complexity of size and location variability. This automatic method…

医学物理 · 物理学 2017-06-21 Neha Rani , Sharda Vashisth

Understanding the dynamics of brain tumor progression is essential for optimal treatment planning. Cast in a mathematical formulation, it is typically viewed as evaluation of a system of partial differential equations, wherein the…

Magnetic resonance spectroscopy (MRS) is a non-invasive technique to measure the metabolic composition of tissues, offering valuable insights into neurological disorders, tumor detection, and other metabolic dysfunctions. However, accurate…

The diagnosis and segmentation of tumors using any medical diagnostic tool can be challenging due to the varying nature of this pathology. Magnetic Reso- nance Imaging (MRI) is an established diagnostic tool for various diseases and…

计算机视觉与模式识别 · 计算机科学 2017-11-01 Tanvi Gupta , Pranay Manocha , Tapan K. Gandhi , RK Gupta , BK Panigrahi

The brain tumor is the most aggressive kind of tumor and can cause low life expectancy if diagnosed at the later stages. Manual identification of brain tumors is tedious and prone to errors. Misdiagnosis can lead to false treatment and thus…

图像与视频处理 · 电气工程与系统科学 2022-08-02 Dmytro Filatov , Ghulam Nabi Ahmad Hassan Yar