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Gross chromosomal rearrangements have the potential to be evolutionarily advantageous to an adapting organism. The generation of a hybrid species increases opportunity for recombination by bringing together two homologous genomes. We sought…

基因组学 · 定量生物学 2015-06-17 Sarah K. Hewitt , Ian Donaldson , Simon C. Lovell , Daniela Delneri

In 8 years of operation, the Large Area Telescope (LAT) on the Fermi satellite has impacted our understanding of gamma-ray pulsars dramatically. The LAT now sees over two hundred pulsars: the largest class of GeV sources in the Milky Way.…

高能天体物理现象 · 物理学 2017-06-13 David A. Smith , Lucas Guillemot , Matthew Kerr , Cherry Ng , Ewan Barr

Next-generation sequencing technologies provide a revolutionary tool for generating gene expression data. Starting with a fixed RNA sample, they construct a library of millions of differentially abundant short sequence tags or "reads",…

定量方法 · 定量生物学 2014-05-13 Dimitrios V. Vavoulis , Julian Gough

A host-parasite model is considered for a population of cells that can be of two types, A or B, and exhibits unilateral reproduction: while a B-cell always splits into two cells of the same type, the two daughter cells of an A-cell can be…

概率论 · 数学 2013-02-06 Gerold Alsmeyer , Sören Gröttrup

Details of how the primordial plasma recombined and how the universe later reionized are currently somewhat uncertain. This uncertainty can restrict the accuracy of cosmological parameter measurements from the Cosmic Microwave Background…

天体物理学 · 物理学 2008-11-26 Antony Lewis , Jochen Weller , Richard Battye

Background: Duplication of genes is important for evolution of molecular networks. Many authors have therefore considered gene duplication as a driving force in shaping the topology of molecular networks. In particular it has been noted…

种群与进化 · 定量生物学 2009-11-13 Jakob Enemark , Kim Sneppen

The formation of DNA loops by proteins and protein complexes that bind at distal DNA sites plays a central role in many cellular processes, such as transcription, recombination, and replication. Here we review the basic thermodynamic…

分子网络 · 定量生物学 2007-05-23 Jose M. G. Vilar , Leonor Saiz

We study the evolution of stars that may be the progenitors of long-soft gamma-ray burst (GRBs) -- rotating naked helium stars presumed to have lost their envelopes to winds or companions. Our aim is to investigate the formation and…

天体物理学 · 物理学 2009-12-30 Robert G. Izzard , Enrico Ramirez-Ruiz , Christopher A. Tout

Inference of the reproduction number through time is of vital importance during an epidemic outbreak. Typically, epidemiologists tackle this using observed prevalence or incidence data. However, prevalence and incidence data alone is often…

统计方法学 · 统计学 2026-03-16 Alicia Gill , Jere Koskela , Xavier Didelot , Richard G. Everitt

Inconsistencies regarding the nature of globular cluster multiple population radial distributions is a matter for concern given their role in testing or validating cluster dynamical evolution modeling. In this study, we present a…

星系天体物理 · 物理学 2021-05-12 Willem B. Hoogendam , Jason P. Smolinski

DNA renaturation is the recombination of two complementary single strands to form a double helix. It is experimentally known that renaturation proceeds through the formation of a double stranded nucleus of several base pairs (the rate…

软凝聚态物质 · 物理学 2010-04-12 A. Ferrantini , M. Baiesi , E. Carlon

How a nano-searcher finds its nano-target is a general problem in non-equilibrium statistical physics. It becomes vital when the searcher is a damaged DNA fragment trying to find its counterpart on the intact homologous chromosome. If the…

生物物理 · 物理学 2016-06-30 Scott Atwell , Aurélie Dupont , Daniel Migliozzi , Jean-Louis Viovy , Giovanni Cappello

Processes of ionization and recombination often influence significantly the observed spectrum produced by symbiotic stars in a very wide wavelength region. Properties of the nebular spectrum provide important information on some fundamental…

天体物理学 · 物理学 2007-05-23 Augustin Skopal

Although planets have been found orbiting binary systems, whether they can survive binary interactions is debated. While the tightest-orbit binaries should host the most dynamically stable and long-lived circumbinary planetary systems, they…

地球与行星天体物理 · 物理学 2024-10-28 Zepei Xing , Santiago Torres , Ylva Götberg , Alessandro A. Trani , Valeriya Korol , Jorge Cuadra

Secondary contact between divergent populations or incipient species may result in the exchange and introgression of genomic material. We develop a simple DNA sequence measure, called Gmin, which is designed to identify genomic regions…

种群与进化 · 定量生物学 2017-02-08 Anthony J. Geneva , Sarah B. Kingan , Daniel Garrigan

We report the splitting of an oscillating DNA circuit into $\sim 700$ droplets with picoliter volumes. Upon incubation at constant temperature, the droplets display sustained oscillations that can be observed for more than a day.…

Charge carrier recombination is studied in operational organic solar cells made from the polymer:fullerene system PCDTBT:PC71BM (poly[N-9"-heptadecanyl-2,7-carbazole-alt-5,5-(4',7'-di-2-thienyl-2',1',3'-benzothiadiazole)] :…

Understanding how viral mutant spectra organize and explore genotype space is essential for unraveling the mechanisms driving evolution at the finest scale. Here we use deep-sequencing data of an amplicon in the A2 protein of the RNA…

种群与进化 · 定量生物学 2024-11-12 Luis F Seoane , Henry Secaira-Morocho , Ester Lázaro , Susanna Manrubia

The var genes of the human malaria parasite Plasmodium falciparum present a challenge to population geneticists due to their extreme diversity, which is generated by high rates of recombination. These genes encode a primary antigen protein…

基因组学 · 定量生物学 2013-10-22 Daniel B. Larremore , Aaron Clauset , Caroline O. Buckee

DNA is not only the genetic material of life, but also a favorable material for a new computing model. Various research works based on DNA computing have been carried out in recent years. DNA sequence design is the foundation of such…

新兴技术 · 计算机科学 2023-11-10 Yao Yao , Xun Zhang , Xin Liu , Yuan Liu , Xiaokang Zhang , Qiang Zhang